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Chemical Structure| 31460-03-4 Chemical Structure| 31460-03-4

Structure of 31460-03-4

Chemical Structure| 31460-03-4

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Product Details of [ 31460-03-4 ]

CAS No. :31460-03-4
Formula : C11H23O5P
M.W : 266.27
SMILES Code : CC(P(OCC)(OCC)=O)C(OC(C)(C)C)=O

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Application In Synthesis of [ 31460-03-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 31460-03-4 ]

[ 31460-03-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 31460-03-4 ]
  • [ 67808-64-4 ]
  • [ 1311290-72-8 ]
YieldReaction ConditionsOperation in experiment
M-12 (2.08 g, 7.8 mmol) was dissolved in tetrahydrofuran (30 mL), 60percent sodium hydride (0.37 g, 9.25 mmol) was added at 0°C, and the mixture was stirred for 30 min.To the reaction mixture was added a solution of 5-formyl-2-thiophenecarboxylic acid methyl ester (1.02 g, 6.0 mmol) in tetrahydrofuran (5 mL), and the mixture was stirred at room temperature overnight.The solvent was evaporated, and the residue was partitioned between ethyl acetate and 1N hydrochloric acid, and washed successively with water and saturated brine.After drying over anhydrous magnesium sulfate, the residue was purified by silica gel column chromatography to give the title compound (1.18 g).1H-NMR(300MHz, CDCl3) delta 7.75(1H, d, J=4.2Hz), 7.69(1H, s), 7.19(1H, d, J=4.2Hz), 3.90(3H, s), 2.19(3H, s), 1.54(9H, s).
 

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