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Chemical Structure| 31709-51-0 Chemical Structure| 31709-51-0

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Chemical Structure| 31709-51-0

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Product Details of [ 31709-51-0 ]

CAS No. :31709-51-0
Formula : C9H6FNO2
M.W : 179.15
SMILES Code : O=C1CC(C2=CC=C(F)C=C2)=NO1

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Application In Synthesis of [ 31709-51-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 31709-51-0 ]

[ 31709-51-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 31686-94-9 ]
  • [ 31709-51-0 ]
YieldReaction ConditionsOperation in experiment
78% With hydroxylamine hydrochloride; potassium carbonate; In ethanol; water; at 20℃; for 18h; To a stirred solution of Intermediate lA (12 g, 57.1 mmol) and hydroxylamine hydrochloride (4.36 g, 62.8 mmol) in ethanol (100 mL) and water (100 mL) was added K2CO3 (3.94 g, 28.5 mmol) and stirred at room temperature for 18 h. Ethanol was removed under reduced pressure the yellow solid separated was filtered and dried to afford Intermediate 69A (8 g, 78%). This was used to the next step without further purification. MS(ES): m/z = 178 [M-H]+; 1H NMR (400 MHz, chloroform-d) delta ppm 7.65 - 7.77 (m, 2H), 7.11 - 7.23 (m, 2H), 3.79 (s, 2H)
 

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