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Chemical Structure| 3183-22-0 Chemical Structure| 3183-22-0

Structure of 3183-22-0

Chemical Structure| 3183-22-0

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Product Details of [ 3183-22-0 ]

CAS No. :3183-22-0
Formula : C7H15NO2
M.W : 145.20
SMILES Code : O=C(OCC)CNC(C)C
MDL No. :MFCD11149656

Safety of [ 3183-22-0 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H314
Precautionary Statements:P301+P330+P331-P303+P361+P353-P363-P304+P340-P310-P321-P260-P264-P280-P305+P351+P338-P405-P501
Class:8
UN#:2735
Packing Group:

Application In Synthesis of [ 3183-22-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 3183-22-0 ]

[ 3183-22-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 3183-22-0 ]
  • [ 59237-53-5 ]
  • [ 1236119-52-0 ]
YieldReaction ConditionsOperation in experiment
83% at 20 - 90℃;Neat (no solvent); Inert atmosphere; Methyl 6-chloro-5-nitronicotinate (2 g, 9.23 mmol) was added to ethyl 2-(isopropylamino) acetate (5.0 g, 34.5 mmol) neat while stirring at room temperature. The viscous yellow reaction was heated to 90° C. for one h and then allowed to cool back to room temperature. The reaction was diluted with dichloromethane (20 mL) and purified via column chromatography (220 g SiO2, 20-30percent gradient, ethyl acetate in hexanes) to yield the title compound (2.39 g, 83percent) as a yellow oil. [M+H] calc'd for C14H19N3O6, 326; found, 326.
 

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