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Chemical Structure| 32081-26-8 Chemical Structure| 32081-26-8

Structure of 32081-26-8

Chemical Structure| 32081-26-8

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Product Details of [ 32081-26-8 ]

CAS No. :32081-26-8
Formula : C19H11NO
M.W : 269.30
SMILES Code : O=C1C2=C(C=CC=C2)N3C4=C(C5=C3C=CC=C5)C=CC=C14

Safety of [ 32081-26-8 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Application In Synthesis of [ 32081-26-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 32081-26-8 ]

[ 32081-26-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 902518-11-0 ]
  • [ 32081-26-8 ]
  • 8,8'-spirobi[indolo[3,2,1-de]acridine] [ No CAS ]
YieldReaction ConditionsOperation in experiment
60% In a dry three-neck flask, 1.6M n-BuLi in hexane (3.9mL, 6.2mmol, 15percentsolution) was added dropwise to a solution of <strong>[902518-11-0]9-(2-bromophenyl)-9H-carbazole</strong> (2.0g, 6.2mmol) in THF at?78°C under nitrogen. After stirring the mixture for 1hat this temperature, 8H-indolo[3,2,1-de]acridin-8-one (1.7g, 6.2mmol) was added dropwise into the mixture with stirring for 2h and then stirred the mixture for 12hat the room temperature, which was poured into water and extracted with CH2Cl2 (20mL×3). The organic layer was dried over anhydrous MgSO4 and concentrated this to obtain the crude materials by a rotary evaporator. Moreover, put the crude compound into acetic acid (20mL) with a little HCl and heated the mixture to reflux for 4h. Then, poured water (30mL) into the mixture and extracted with CH2Cl2 (20mL×3). Dried the organic layer over anhydrous MgSO4 and concentrated this using a rotary evaporator. The crude materials were purified by silica gel column chromatography (petroleum ether/CH2Cl2=6: 1 v/v) to obtain a white solid 1.2g, 60percent. 1H NMR (400MHz, CDCl3, TMS) delta: 8.23 (d, J=8.4Hz, 2H), 8.18?8.11 (m, 4H), 7.79 (d, J=7.6Hz, 2H), 7.57 (t, J=7.6Hz, 2H), 7.34 (t, J=7.6Hz, 2H), 7.26 (t, J=7.2Hz, 2H), 7.04 (t, J=8.0Hz, 4H), 6.83 (t, J=8.8Hz, 4H).13C NMR (126MHz, CDCl3) delta: 138.42, 135.11, 134.98, 134.00, 133.64, 130.00, 127.64, 126.75, 126.57, 126.26, 123.62, 122.99, 122.04, 121.26, 120.99, 117.78, 113.84, 113.45, 47.80. HRMS (m/z): [M+H]? calcd for C37H22N2, 495.1861; found, 495.1886.
 

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