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Chemical Structure| 326-63-6 Chemical Structure| 326-63-6

Structure of 326-63-6

Chemical Structure| 326-63-6

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Product Details of [ 326-63-6 ]

CAS No. :326-63-6
Formula : C8H8FNO
M.W : 153.15
SMILES Code : O=C(N)CC1=CC=CC=C1F
MDL No. :MFCD11643209

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Application In Synthesis of [ 326-63-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 326-63-6 ]

[ 326-63-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 326-62-5 ]
  • [ 326-63-6 ]
YieldReaction ConditionsOperation in experiment
With dihydrogen peroxide; potassium carbonate; In water; dimethyl sulfoxide; at 0 - 25℃; for 0.5h; General procedure: A stirred solution of 2-fluoro-benzonitrile (0.88 g) and K2CO3 (0.15 g) in DMSO (3 mL), cooled in an ice bath, was added 35% H2O2 (1 mL). The mixture was allowed to warm up to 25 C for 30 min, poured into H2O (50 mL), and the resulting solid was collected and washed with Et2O to give 23b as white solid: mp 109-111 C (lit.7 116-119C); 1H NMR (400 MHz, Acetone-d6) delta: 7.91 (td, J = 7.7, 1.8 Hz, 1H), 7.57 (tdd, J = 7.2, 5.2, 1.9 Hz, 1H), 7.30 (tt, J = 6.2, 3.1 Hz, 1H), 7.24 (dd, J = 11.5, 8.3 Hz, 1H).
 

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