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Chemical Structure| 331821-29-5 Chemical Structure| 331821-29-5

Structure of 331821-29-5

Chemical Structure| 331821-29-5

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Product Details of [ 331821-29-5 ]

CAS No. :331821-29-5
Formula : C15H9BrO3
M.W : 317.13
SMILES Code : O=C1C(C2=CC=C(C=C2)Br)=CC3=C(C=C(C=C3)O)O1
MDL No. :MFCD02660623

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Application In Synthesis of [ 331821-29-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 331821-29-5 ]

[ 331821-29-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 50-00-0 ]
  • [ 331821-29-5 ]
  • [ 494-52-0 ]
  • 7-hydroxy-8-[(2S)-2-pyridin-3-ylpyridin-1-yl]methyl}-3-(4-bromophenyl)-2H-chromen-2-one [ No CAS ]
YieldReaction ConditionsOperation in experiment
94% With dmap; at 78℃; General procedure: The appropriate 7-hydroxycoumarin 1a-h (2 mmol) in refluxing anhydrous EtOH (25-30 mL) was treated with anabasine (2.5 mmol), paraformaldehyde (90 mg,3 mmol), and DMAP (2-5 mg), and refluxed for 20-30 h. The end of the reaction was determined by TLC. The mixture wascooled and diluted with hexane. The resulting precipitate was filtered off, dried, and crystallized from i-PrOH-hexane orpurified by column chromatography with elution by EtOAc.
 

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