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Chemical Structure| 3338-32-7 Chemical Structure| 3338-32-7

Structure of Cbz-Asp(OtBu)-Osu
CAS No.: 3338-32-7

Chemical Structure| 3338-32-7

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Product Details of [ 3338-32-7 ]

CAS No. :3338-32-7
Formula : C20H24N2O8
M.W : 420.41
SMILES Code : O=C(ON1C(CCC1=O)=O)[C@@H](NC(OCC2=CC=CC=C2)=O)CC(OC(C)(C)C)=O
MDL No. :MFCD00153328

Safety of [ 3338-32-7 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P233-P260-P261-P264-P270-P271-P280-P301+P312-P302+P352-P304-P304+P340-P305+P351+P338-P312-P321-P330-P332+P313-P337+P313-P340-P362-P403-P403+P233-P405-P501

Application In Synthesis of [ 3338-32-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 3338-32-7 ]

[ 3338-32-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 3338-32-7 ]
  • [ 53838-27-0 ]
  • Z-Asp(OBu<SUP>t</SUP>)-Glu(OBu<SUP>t</SUP>)-OCH<SUB>3</SUB> [ No CAS ]
YieldReaction ConditionsOperation in experiment
80.3% In N,N-dimethyl-formamide; at 20℃; for 12h; 10.0 g (46.3 mmol) of H-Glu(OBut)-OCH3 were dissolved in 300 ml of dimethyl formamide; 19.7 g (47 mmol) of Z-Asp(OBut)-ONSu were then added at room temperature. After 12 hours (control - TLC in the system chloroform:methonol: acetic acid - 9:1:0.5 B) the reaction mixture was boiled down, the residue was dissolved in ethyl acetate, washed sequentially with 2% sulphuric acid and water, dried over Na2SO4 and boiled down. The residue was dissolved in 100 ml of ester. The substance crystallized at 4 C. The sediment was filtered out, washed with ester, and dried in air. (0028) 20 g (80.3 %) of chromatographically homogeneous substance were obtained.
 

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