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[ CAS No. 3392-09-4 ]

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Cat. No.: {[proInfo.prAm]}
2D
Chemical Structure| 3392-09-4
Chemical Structure| 3392-09-4
Structure of 3392-09-4 *Storage: {[proInfo.prStorage]}

Quality Control of [ 3392-09-4 ]

Purity: {[proInfo.showProBatch.pb_purity]}

Related Doc. of [ 3392-09-4 ]

SDS

Product Details of [ 3392-09-4 ]

CAS No. :3392-09-4MDL No. :MFCD00037913
Formula :C15H24N2O6Boiling Point :-
Linear Structure Formula :(CH3)3COCONHCHCH2CH(CH3)2CO2NC4H4O2InChI Key :WXRGJQZMGGGTSS-JTQLQIEISA-N
M.W :328.36Pubchem ID :11023929
Synonyms :

Computed Properties of [ 3392-09-4 ]

TPSA : - H-Bond Acceptor Count : -
XLogP3 : - H-Bond Donor Count : -
SP3 : - Rotatable Bond Count : -

Safety of [ 3392-09-4 ]

Signal Word:WarningClassN/A
Precautionary Statements:P261-P305+P351+P338UN#:N/A
Hazard Statements:H315-H319-H335Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 3392-09-4 ]

  • Downstream synthetic route of [ 3392-09-4 ]

[ 3392-09-4 ] Synthesis Path-Downstream   1~10

  • 1
  • [ 3392-09-4 ]
  • [ 676261-87-3 ]
  • [ 676262-11-6 ]
  • 2
  • [ 3392-09-4 ]
  • [ 61-90-5 ]
  • [ 73401-65-7 ]
  • 3
  • [ 13139-15-6 ]
  • O-succinimidyl-1,3-dimethyl-1,3-trimethyleneuronium tetrafluoroborate [ No CAS ]
  • [ 3392-09-4 ]
  • 4
  • [ 3392-09-4 ]
  • (S)-2-({(S)-1-[(S)-2-[(R)-3-(Acetylamino-methylsulfanyl)-2-((S)-2-amino-3-methyl-butyrylamino)-propionylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carbonyl}-amino)-4-carbamoyl-butyric acid; compound with trifluoro-acetic acid [ No CAS ]
  • [ 406712-32-1 ]
  • 5
  • [ 3392-09-4 ]
  • [ 1758-80-1 ]
  • [ 295321-36-7 ]
  • 6
  • [ 3392-09-4 ]
  • [ 1616761-70-6 ]
  • C24H37N3O6 [ No CAS ]
YieldReaction ConditionsOperation in experiment
68% With hydrogen; In tetrahydrofuran; at 20℃; for 4h; To a solution of N02-G0x-Gly-0Bn[21 (1.70 g, 6.06 mmol, 1.0 equiv) in THF (60 mL) was added [3392-09-4]Boc-Leu-OSu (2.98 g, 9.09 mmol, 1.5 equiv) and Raney Ni (slurry in H20, 6.0 mL). The solution was placed under an atmosphere of nitrogen, evacuated and filled with hydrogen (balloon). The reaction mixture was stirred vigorously for 4.0 h at room temperature. Then, the mixture was filtered through a plug of Celite eluting with EtOAc, concentrated under reduced pressure, the filtrate was suspended in EtOAc (50 mL), washed with saturated Na2C03 (3 x 50 mL), dried over Na2S04 and concentrated in vacuo. Boc-Leu-GOx-Gly-OBn (23) was afforded after purification by column chromatography (Si02, EtOAc/PE 3:2) as a colourless viscous oil (1.91 g, 4.13 mmol, 68%).
  • 7
  • [ 3392-09-4 ]
  • C19H25N3O5*C2HF3O [ No CAS ]
  • tert-butyl ((S)-1-(((3S,6S,11R,E)-3-(4-hydroxybenzyl)-6-isopropyl-2,5,8-trioxo-1-oxa-4,7-diazacyclododec-9-en-11-yl)amino)-3-methyl-1-oxopentan-2-yl)carbamate [ No CAS ]
YieldReaction ConditionsOperation in experiment
40 mg With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 115℃; for 1h; [0283] To a solution of compound 12 A (50 mg, 102.16 umol, TFA) and (2,5- dioxopyrrolidin- 1 -yl) (26^ 2-(teri-butoxycarbonylamino)-4-methyl-pentanoate (67 g, 204.31 umol) in DMF (3 mL) was added DIEA (510.79 umol, 0.09 mL), the mixture was stirred at 15 C for lh. The reaction mixture was diluted with wrater (20 mL), extracted with EA (10 mL x 2), the organic layers were washed with brine (20 mL), dried over Na2S04, filtered and concentrated to give a residue. The residue was purified by preparatory- TLC (EA: MeOH = 30: 1). Compound 12 (40 mg, yield: 65.2%) as white solid was obtained. *H NMR (400MHz, Methanol-^) d 7.08 - 6.98 (m, 2H), 6.75 - 6.63 (m, 2H), 6.57 - 6.39 (m, 1H), 6.16 (d, J= 14.8 Hz, 1H), 4.85 - 4.49 (m, 3H), 4.19 (d, J= 7.0 Hz, 1H), 3.90 - 3.70 (m, 2H), 3.18 - 2.87 (m, 2H), 1.93 - 1.79 (m, IH), 1.76 - 1.63 (m, IH), 1.60 - 1.50 (m, 2H), 1.47 - 1.40 (m, 9H), 1.00 - 0.95 (m, 6H), 0.91 (d, J = 6.8 Hz, 3H), 0.79 (d, J = 6.8 Hz, 3H). MS (ESI) m/z (M+Na)+611.0.
  • 8
  • [ 3392-09-4 ]
  • H-Glu(O-cHex)-Lys(2-Adoc)-Gln-Lys(2-Adoc)-OBzl*HCl [ No CAS ]
  • [ 249302-39-4 ]
  • 9
  • [ 3392-09-4 ]
  • H-Leu-Gln-OBzl*HCl [ No CAS ]
  • [ 249302-40-7 ]
  • 10
  • [ 3392-09-4 ]
  • [ 2419-53-6 ]
  • [ 170220-88-9 ]
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