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Chemical Structure| 3392-10-7 Chemical Structure| 3392-10-7

Structure of 3392-10-7

Chemical Structure| 3392-10-7

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Product Details of [ 3392-10-7 ]

CAS No. :3392-10-7
Formula : C14H20N2O6
M.W : 312.32
SMILES Code : CC(C)(C)OC(N1[C@H](C(ON2C(CCC2=O)=O)=O)CCC1)=O
MDL No. :MFCD00037902

Safety of [ 3392-10-7 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H317
Precautionary Statements:P280

Application In Synthesis of [ 3392-10-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 3392-10-7 ]

[ 3392-10-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 35661-51-9 ]
  • [ 3392-10-7 ]
  • [ 947528-18-9 ]
YieldReaction ConditionsOperation in experiment
96% In dichloromethane; at 20℃; To the solution of Boc-L-Proline succinamide ester (0.5 g, 1.6 mmol) in DCM (15 mL) Fmoc- hydrazine (0.41 g, 1.6 mmol) was added and the mixture was stirred overnight at room temperature. The reaction mixture was diluted with ethyl acetate (50 mL) and washed with 1N HCl (15 mL), 10percent NaHCO3 (15 mL), brine (15 mL), dried (Na2SO4) and concentrated to give 701 mg (96percent) of product as a white solid; mp. 81-82°C. Rf = 0.3 (1:1 EtOAc/Pentane) [alpha]D -59.8 (c 0.5, MeOH) 1H NMR (200 MHz, CDCl3) delta (ppm) 8.85 (br s, 1H), 7.65 (d, J = 7.24 Hz, 2H), 7.5 (d, J = 7.24 Hz, 2H), 7.11-7.33 (m, 5H), 4.25-4.34 (m, 3H), 4.1-4.17 (m, 1H), 3.37 (m, 2H), 1.69-2.08 (m, 4H), 1.38 (s, 9H). 13C NMR (200 MHz, CDCl3) delta (ppm) 172.02, 171.17, 156.07, 143.56, 141.23, 127.73, 127.11, 125.15, 119.93, 80.85, 67.92, 58.38, 47.1, 46.9, 28.36, 24.42, 14.17. IR (KBr) nu 4000 - 3277 (br), 2977, 1696 (br), 1451, 1405, 1366, 1246, 1164, 759, 740 cm-1.
 

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