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Chemical Structure| 34274-23-2 Chemical Structure| 34274-23-2

Structure of 34274-23-2

Chemical Structure| 34274-23-2

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Product Details of [ 34274-23-2 ]

CAS No. :34274-23-2
Formula : C6H8N2O2
M.W : 140.14
SMILES Code : O=C1N=C(COC)NC=C1
MDL No. :MFCD14690997

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Application In Synthesis of [ 34274-23-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 34274-23-2 ]

[ 34274-23-2 ] Synthesis Path-Downstream   1~2

  • 1
  • ethyl formylacetate sodium salt [ No CAS ]
  • [ 1903-91-9 ]
  • [ 34274-23-2 ]
YieldReaction ConditionsOperation in experiment
In water; (a) A mixture of 120 g of <strong>[1903-91-9]methoxyacetamidine hydrochloride</strong> and 300 g of ethyl formylacetate sodium salt in 1.5 1 of water was stirred at room temperature for 3 days. The reaction solution was concentrated and then acidified with hydrochloric acid and extracted with hydrochloric acid and extracted with dichloromethane. Purification by column chromatography resulted in 100 g of 2-methoxymethyl-4-pyrimidone (melting point 126 C.).
  • 2
  • ethyl formyl acetate sodium salt [ No CAS ]
  • [ 1903-91-9 ]
  • [ 34274-23-2 ]
YieldReaction ConditionsOperation in experiment
In water; (i) A mixture of <strong>[1903-91-9]methoxyacetamidine hydrochloride</strong> (57 g) and ethyl formyl acetate sodium salt (150.5 g) in water (670 ml) were stirred at room temperature for 3 days. The volume was reduced and the solution acidified, saturated with sodium chloride and extracted with chloroform. After drying (MgSO4), the extracts were stripped to a solid which was triturated with ether to give 2-methoxymethyl-4-pyrimidone (53.5 g) m.p. 125-7.
 

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