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Chemical Structure| 349666-24-6 Chemical Structure| 349666-24-6
Chemical Structure| 349666-24-6

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4,4,5,5-Tetramethyl-2-pyren-1-yl-1,3,2-dioxaborolane is a boronate ester derivative used in Suzuki coupling reactions with potential applications in drug synthesis.

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Product Details of 4,4,5,5-Tetramethyl-2-pyren-1-yl-1,3,2-dioxaborolane

CAS No. :349666-24-6
Formula : C22H21BO2
M.W : 328.21
SMILES Code : CC1(C)C(C)(C)OB(C2=C(C3=C45)C=CC5=CC=CC4=CC=C3C=C2)O1
MDL No. :MFCD11505919
Boiling Point : No data available
InChI Key :PHBXSUBZBOVYKO-UHFFFAOYSA-N
Pubchem ID :11077956

Safety of 4,4,5,5-Tetramethyl-2-pyren-1-yl-1,3,2-dioxaborolane

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of 4,4,5,5-Tetramethyl-2-pyren-1-yl-1,3,2-dioxaborolane

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 349666-24-6 ]

[ 349666-24-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 851786-15-7 ]
  • [ 349666-24-6 ]
  • C56H49BrN2O4 [ No CAS ]
YieldReaction ConditionsOperation in experiment
With tetrakis(triphenylphosphine) palladium(0); In tetrahydrofuran; at 85℃; for 4.5h;Inert atmosphere; The intermediate M2,0.41g borate 0.83g and 0.46g tetrakistriphenylphosphine palladium was added to phosphorus containing water removal 12mLTHF (tetrahydrofuran) three-necked round bottom reaction flask.Slowly warmed to 85 under an argon atmosphere.TLC detection reaction process, to walk the plank raw spots disappear stop the reaction.4.5h the reaction ended, 45 deg.] C under reduced pressure (degree of vacuum less than 133Pa) was removed by distillation THF (tetrahydrofuran), and then with dichloromethane: petroleum ether (v: v) = 3: 1 was dissolved, and used as the eluent, column chromatography Analysis of separation and purification, to give a pink product M3.
 

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