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Chemical Structure| 351370-67-7 Chemical Structure| 351370-67-7

Structure of 351370-67-7

Chemical Structure| 351370-67-7

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Product Details of [ 351370-67-7 ]

CAS No. :351370-67-7
Formula : C14H21NO
M.W : 219.32
SMILES Code : CC(O)(C1CN(CC2=CC=CC=C2)CC1)C
MDL No. :MFCD06858467

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Application In Synthesis of [ 351370-67-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 351370-67-7 ]

[ 351370-67-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 17012-21-4 ]
  • [ 75-16-1 ]
  • [ 351370-67-7 ]
YieldReaction ConditionsOperation in experiment
STEP 1. 2-(1-BENZYLPYRROLIDIN-3-YL)PROPAN-2-OL To a cooled (0 C.) solution of methyl N-benzyl-3-pyrrolidinecarboxylate (1.013 g, 4.62 mmol, Tyger) in THF (50 mL) was added methylmagnesium bromide (3.0M solution in diethyl ether, 7.5 mL, 22.50 mmol) dropwise. After 30 min the mixture was warmed to rt for 2 h. The reaction was cooled (0 C.) and carefully quenched with saturated NH4Cl (50 mL) and then diluted with water (25 mL). The mixture was extracted with EtOAc (3*50 mL) and the combined organic layers were washed with brine and dried over Na2SO4. Concentration in vacuo gave a light-yellow oil. m/z: 220.0 [M+1].
 

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