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[ CAS No. 354793-04-7 ]

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Cat. No.: {[proInfo.prAm]}
2D
Chemical Structure| 354793-04-7
Chemical Structure| 354793-04-7
Structure of 354793-04-7 *Storage: {[proInfo.prStorage]}

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SDS

Product Details of [ 354793-04-7 ]

CAS No. :354793-04-7MDL No. :MFCD11973607
Formula : C10H8N2O4 Boiling Point : -
Linear Structure Formula :-InChI Key :N/A
M.W :220.18Pubchem ID :23847563
Synonyms :

Computed Properties of [ 354793-04-7 ]

TPSA : 84.5 H-Bond Acceptor Count : 4
XLogP3 : 0.3 H-Bond Donor Count : 2
SP3 : 0.10 Rotatable Bond Count : 2

Safety of [ 354793-04-7 ]

Signal Word:WarningClassN/A
Precautionary Statements:P280-P305+P351+P338UN#:N/A
Hazard Statements:H302Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 354793-04-7 ]

  • Upstream synthesis route of [ 354793-04-7 ]
  • Downstream synthetic route of [ 354793-04-7 ]

[ 354793-04-7 ] Synthesis Path-Upstream   1~1

  • 1
  • [ 36692-49-6 ]
  • [ 95-92-1 ]
  • [ 354793-04-7 ]
YieldReaction ConditionsOperation in experiment
90% for 88.00 h; Reflux Condensation of methyl 3 ,4-diaminobenzoate with diethyl oxalate (8.0 equivalents) in toluene (10 volumes) was carried out at reflux for 88 hours. After complete conversion, the mixture was concentrated to a residue which was washed with MTBE. After drying intermediate 184 was obtained in 90percent yield.
90% for 88.00 h; Reflux Condensation of methyl 3,4-diaminobenzoate with diethyl oxalate (8.0 equivalents) in toluene (10 volumes) was carried out at reflux for 88 hours. After complete conversion, the mixture was concentrated to a residue which was washed with methyl tert-butyl ether. After drying intermediate 25 was obtained in 90percent yield.
Reference: [1] Patent: WO2017/60406, 2017, A1. Location in patent: Page/Page column 172
[2] Patent: WO2018/178280, 2018, A1. Location in patent: Page/Page column 78
[3] Patent: US2004/192698, 2004, A1. Location in patent: Page/Page column 18
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