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Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
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Chemical Structure| 3603-43-8 Chemical Structure| 3603-43-8

Structure of 3603-43-8

Chemical Structure| 3603-43-8

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Product Details of [ 3603-43-8 ]

CAS No. :3603-43-8
Formula : C9H19NO2
M.W : 173.25
SMILES Code : OCCOCCN1CCCCC1
MDL No. :MFCD01098144

Safety of [ 3603-43-8 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301-H311-H315-H318-H331-H373
Precautionary Statements:P261-P280-P301+P310-P305+P351+P338-P311
Class:6.1
UN#:2811
Packing Group:

Application In Synthesis of [ 3603-43-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 3603-43-8 ]

[ 3603-43-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 110-89-4 ]
  • [ 118591-58-5 ]
  • [ 3603-43-8 ]
YieldReaction ConditionsOperation in experiment
42% With potassium carbonate; In 1,4-dioxane; at 70℃; Compound 1-3 (2.6 g, 10 mmol) was dissolved in 1,4-dioxane (40 mL), followed by addition of piperidine 13-1 (2.52 g, 30 mmol), and potassium carbonate (2.76 g, 20 mmol) was added under stirring, followed by stirring the reaction overnight under conditions of 70° C. and a closed reaction system, TLC monitoring showed that the starting material 1-3 was completely reacted. The solvent was removed under reduced pressure to obtain a concentrated residue. The concentrated residue was dispensed with dichloromethane (20 mL), an appropriate amount of silica gel was added and the sample was stirred, spin-dried under reduced pressure and directly placed on a silica gel column for column chromatographic purification, with an eluent (dichloromethane:methanol=20/1-5/1) to obtain the target product 13-2 (0.73 g, 42percent) as a pale yellow oil, LC-MS: m/z=174[M+H]+.
 

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