[ CAS No. 36236-76-7 ] {[proInfo.proName]}

Name: 36236-76-7|4-(Bromomethyl)-2,2-dimethyl-1,3-dioxolane|98%
Brand: Ambeed
SKU: A761451
Price: 12.0 USD
Availability: InStock
Rating: 96 (28 reviews)

,{[proInfo.pro_purity]}

Cat. No.: {[proInfo.prAm]}

HazMat Fee +

There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type	HazMat fee for 500 gram (Estimated)
Excepted Quantity	USD 0.00
Limited Quantity	USD 15-60
Inaccessible (Haz class 6.1), Domestic	USD 80+
Inaccessible (Haz class 6.1), International	USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic	USD 100+
Accessible (Haz class 3, 4, 5 or 8), International	USD 200+

DV 2D 3D

3d Animation Molecule Structure of 36236-76-7

Structure of 36236-76-7 * Storage: {[proInfo.prStorage]}

Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

For Research Only 110K+ Compounds Competitive Price 1-2 Day Shipping

Quality Control of [ 36236-76-7 ]

COA NMR CNMR HPLC LC-MS

Related Doc. of [ 36236-76-7 ]

SDS Specification

Alternatived Products of [ 36236-76-7 ]

Product Details of [ 36236-76-7 ]

CAS No. :	36236-76-7	MDL No. :	MFCD14584455
Formula :	C₆H₁₁BrO₂	Boiling Point :	-
Linear Structure Formula :	-	InChI Key :	ZOPZKFNSQYCIPP-UHFFFAOYSA-N
M.W :	195.05	Pubchem ID :	169759
Synonyms :

Safety of [ 36236-76-7 ]

Signal Word:	Danger	Class:	8
Precautionary Statements:	P210-P261-P264-P271-P272-P280-P302+P352-P304+P340-P305+P351+P338-P310-P332+P313-P362-P370+P378-P403+P233-P403+P235-P405-P501	UN#:	1760
Hazard Statements:	H315-H318-H335-H317-H227	Packing Group:	Ⅲ
GHS Pictogram:

Application In Synthesis of [ 36236-76-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Upstream synthesis route of [ 36236-76-7 ]
Downstream synthetic route of [ 36236-76-7 ]

[ 36236-76-7 ] Synthesis Path-Upstream 1~6

1
[ 4704-77-2 ]
[ 584-08-7 ]
[ 36236-76-7 ]

Yield	Reaction Conditions	Operation in experiment
53.5%	With sulfuric acid In acetone	EXAMPLE 21 (+-)-N-(2,2-Dimethyl-1,3-dioxolan-4-yl)methyl-N,N-dimethyl-β-hydroxyethyl ammonium bromide Into a 500 milliliter round bottom flask equipped with a magnetic stir bar and drying tube, a solution of 28.0 grams (0.181 mole) of 3-bromo-1,2-propanediol in 200 milliliters of acetone was added. Then, 0.5 milliliter of concentrated sulfuric acid was added and the reaction allowed to proceed at room temperature for 24 hours with continuous stirring. The reaction mixture was neutralized with 13.0 grams of K₂ CO₃ for 30 minutes, the solution was filtered and the solvent evaporated in vacuo. The resulting oil was dissolved in 150 milliliter of ether, extracted three times with 150 milliliter portions of water and the organic layer dried over anhydrous sodium sulfate. The filtered ether was evaporated in vacuo and 100 milliliters of hexanes was added, resulting in two layers. The upper layer was decanted and evaporated in vacuo to provide 19.1 grams (53.5percent) of (2,2-dimethyl-1,3-dioxolan-4-yl)methyl bromide.

Reference： [1] Patent: US5614548, 1997, A,

2
[ 67-64-1 ]
[ 3132-64-7 ]
[ 36236-76-7 ]

Reference： [1] Chemical and Pharmaceutical Bulletin, 1984, vol. 32, # 3, p. 967 - 976

3
[ 4704-77-2 ]
[ 67-64-1 ]
[ 36236-76-7 ]

Reference： [1] Journal of Medicinal Chemistry, 1990, vol. 33, # 3, p. 985 - 992
[2] Tetrahedron Letters, 1984, vol. 25, # 49, p. 5633 - 5636

4
[ 4704-77-2 ]
[ 77-76-9 ]
[ 36236-76-7 ]

Reference： [1] Journal of Organic Chemistry, 1987, vol. 52, # 10, p. 2086 - 2089

5
[ 34832-91-2 ]
[ 36236-76-7 ]

Reference： [1] Russian Journal of General Chemistry, 2008, vol. 78, # 12, p. 2407 - 2408

6
[ 776-74-9 ]
[ 36236-76-7 ]
[ 93551-89-4 ]

Reference： [1] Journal of the Chemical Society, 1953, p. 3572,3574

[ 36236-76-7 ] Synthesis Path-Downstream 1~62

1
2,2-dimethyl-4-phenylthiocarbamoyloximethyl-[1,3]dioxolane [ No CAS ]
[ 776-74-9 ]
[ 36236-76-7 ]
[ 93551-89-4 ]

Reference： [1]Journal of the Chemical Society,1953,p. 3572,3574

2
[ 36236-76-7 ]
[ 4704-77-2 ]

Reference： [1]Bulletin de la Societe Chimique de France,1971,p. 3335 - 3338

3
[ 6859-99-0 ]
[ 36236-76-7 ]
[ 64445-24-5 ]

Reference： [1]Chemical and Pharmaceutical Bulletin,1984,vol. 32,p. 967 - 976

4
[ 5382-16-1 ]
[ 36236-76-7 ]
[ 64445-06-3 ]

Reference： [1]Chemical and Pharmaceutical Bulletin,1984,vol. 32,p. 967 - 976

5
[ 36236-76-7 ]
[ 108-01-0 ]
[ 124581-83-5 ]

Reference： [1]Journal of Medicinal Chemistry,1990,vol. 33,p. 985 - 992

6
[ 36236-76-7 ]
[ 61170-65-8 ]
[ 505-23-7 ]
[ 106976-78-7 ]

Reference： [1]Journal of Organic Chemistry,1987,vol. 52,p. 2086 - 2089

7
[ 36236-76-7 ]
[ 2917-26-2 ]
[ 62244-43-3 ]

Reference： [1]Journal of Organic Chemistry USSR (English Translation),1982,vol. 18,p. 840 - 841
Zhurnal Organicheskoi Khimii,1982,vol. 18,p. 967 - 970

8
[ 36236-76-7 ]
[ 2885-00-9 ]
[ 62244-39-7 ]

Reference： [1]Journal of Organic Chemistry USSR (English Translation),1982,vol. 18,p. 840 - 841
Zhurnal Organicheskoi Khimii,1982,vol. 18,p. 967 - 970

9
[ 36236-76-7 ]
[ 42454-06-8 ]
[ 142103-84-2 ]

Reference： [1]Journal of Medicinal Chemistry,1992,vol. 35,p. 2672 - 2687

10
[ 36236-76-7 ]
[ 38339-95-6 ]
[ 102685-89-2 ]

Reference： [1]Journal of Medicinal Chemistry,1988,vol. 31,p. 1548 - 1557

11
[ 36236-76-7 ]
[ 55055-15-7 ]
2-oxo-2-(1,2-S-isopropylideneglycero)-1,3,2-oxathiophosphorinane [ No CAS ]

Reference： [1]Phosphorus and Sulfur and the Related Elements,1987,vol. 34,p. 109 - 118

12
[ 36236-76-7 ]
[ 55055-15-7 ]
[ 116306-72-0 ]

Reference： [1]Phosphorus and Sulfur and the Related Elements,1987,vol. 34,p. 109 - 118

13
[ 36236-76-7 ]
[ 134461-75-9 ]
[ 87935-99-7 ]

Reference： [1]Tetrahedron,1987,vol. 43,p. 2101 - 2108

14
[ 36236-76-7 ]
[ 116306-72-0 ]
2-oxo-2-(1,2-S-isopropylideneglycero)-1,3,2-oxathiophosphorinane [ No CAS ]

Reference： [1]Phosphorus and Sulfur and the Related Elements,1987,vol. 34,p. 109 - 118

15
[ 4704-77-2 ]
[ 77-76-9 ]
[ 36236-76-7 ]

Reference： [1]Journal of Organic Chemistry,1987,vol. 52,p. 2086 - 2089

16
[ 4704-77-2 ]
[ 67-64-1 ]
[ 36236-76-7 ]

Reference： [1]Journal of Medicinal Chemistry,1990,vol. 33,p. 985 - 992
[2]Tetrahedron Letters,1984,vol. 25,p. 5633 - 5636

17
[ 67-64-1 ]
[ 3132-64-7 ]
[ 36236-76-7 ]

Yield	Reaction Conditions	Operation in experiment
82%	With boron trifluoride diethyl etherate; at 20℃; for 15h;	Synthesis of Compound B1 Procedure: 10 drops of BF3.Et2O are added to 50 mL of anhydrous acetone at room temperature. Epibromohydrin (20.0 g, 146 mmol) is then added dropwise to the reaction medium at room temperature, then the reaction medium is stirred at room temperature for 15 hours. Compound B1 is then isolated by distillation under vacuum. 23.0 g (yield=82%) of a colourless liquid is thus obtained. 1H NMR (CDCl3, 400 MHz): δ (ppm): 4.33 (m, 1H), 4.11 (ddd, 1H, J=8.7 Hz, J=6.1 Hz, J=0.6 Hz), 3.85 (dd, 1H, J=8.7 Hz, J=5.1 Hz), 3.40 (ddd, 1H, J=10.0 Hz, J=4.7 Hz, J=0.6 Hz), 3.29 (dd, 1H, J=10.0 Hz, J=8.1 Hz), 1.42 (s, 3H), 1.33 (s, 3H).

Reference： [1]Chemical and Pharmaceutical Bulletin,1984,vol. 32,p. 967 - 976
[2]Patent: US2020/231605,2020,A1 .Location in patent: Paragraph 0307-0309

Yield	Reaction Conditions	Operation in experiment
		Examples of suitable 5-halo-1,3-dioxolanes and 5-(α-haloalkyl)-1,3-dioxolanes are: ... 5-bromomethyl-2-methyl-1,3-dioxolane 5-bromomethyl-2-isopropyl-1,3-dioxolane 5-chloromethyl-2-isobutyl-1,3-dioxolane 5-bromomethyl-2-tert-butyl-1,3-dioxolane 5-bromomethyl-2,2-dimethyl-1,3-dioxolane 5-bromomethyl-2,2-diethyl-1,3-dioxolane 5-(1,3-dioxolan-5-yl)-1-bromoethane 5-(2-methyl-1,3-dioxolan-5-yl)-1-bromoethane ...

19
[ 776-74-9 ]
(+/-)-phenylthiocarbamic acid <i>O</i>-<2,2-dimethyl-<1,3>dioxolan-4-ylmethyl ester> [ No CAS ]
[ 36236-76-7 ]

Reference： [1]Journal of the Chemical Society,1953,p. 3572,3574

20
(+/-)-toluene-4-sulfonic acid-<2,2-dimethyl-<1,3>dioxolan-4-ylmethyl ester> [ No CAS ]
lithium bromide [ No CAS ]
[ 36236-76-7 ]

Reference： [1]Journal of the American Chemical Society,1952,vol. 74,p. 1361

21
[ 36236-76-7 ]
[ 82670-41-5 ]

Reference： [1]Journal of Organic Chemistry USSR (English Translation),1982,vol. 18,p. 840 - 841
Zhurnal Organicheskoi Khimii,1982,vol. 18,p. 967 - 970

22
[ 36236-76-7 ]
[ 82670-42-6 ]

Reference： [1]Journal of Organic Chemistry USSR (English Translation),1982,vol. 18,p. 840 - 841
Zhurnal Organicheskoi Khimii,1982,vol. 18,p. 967 - 970

23
[ 36236-76-7 ]
2-oxo-2-(1,2-S-isopropylideneglycero)-1,3,2-oxathiophosphorinane [ No CAS ]

Reference： [1]Journal of general chemistry of the USSR,1987,vol. 57,p. 186 - 192
Zhurnal Obshchei Khimii,1987,vol. 57,p. 213 - 221

24
[ 36236-76-7 ]
1,2-S-isopropylideneglycero-3-thiolophosphohomocholine [ No CAS ]

Reference： [1]Journal of general chemistry of the USSR,1987,vol. 57,p. 186 - 192
Zhurnal Obshchei Khimii,1987,vol. 57,p. 213 - 221
[2]Journal of general chemistry of the USSR,1987,vol. 57,p. 186 - 192
Zhurnal Obshchei Khimii,1987,vol. 57,p. 213 - 221
[3]Phosphorus and Sulfur and the Related Elements,1987,vol. 34,p. 109 - 118
[4]Phosphorus and Sulfur and the Related Elements,1987,vol. 34,p. 109 - 118

25
[ 36236-76-7 ]
1,2-S-isopropylideneglycero-3-thiophosphohomocholine [ No CAS ]

Reference： [1]Journal of general chemistry of the USSR,1987,vol. 57,p. 186 - 192
Zhurnal Obshchei Khimii,1987,vol. 57,p. 213 - 221
[2]Phosphorus and Sulfur and the Related Elements,1987,vol. 34,p. 109 - 118

26
[ 36236-76-7 ]
[ 64445-12-1 ]

Reference： [1]Chemical and Pharmaceutical Bulletin,1984,vol. 32,p. 967 - 976

27
[ 36236-76-7 ]
[ 64445-16-5 ]

Reference： [1]Chemical and Pharmaceutical Bulletin,1984,vol. 32,p. 967 - 976

28
[ 36236-76-7 ]
[ 64749-86-6 ]

Reference： [1]Chemical and Pharmaceutical Bulletin,1984,vol. 32,p. 967 - 976

29
[ 36236-76-7 ]
[ 91540-06-6 ]

Reference： [1]Chemical and Pharmaceutical Bulletin,1984,vol. 32,p. 967 - 976

30
[ 36236-76-7 ]
[ 64445-11-0 ]

Reference： [1]Chemical and Pharmaceutical Bulletin,1984,vol. 32,p. 967 - 976

31
[ 36236-76-7 ]
[ 91614-23-2 ]

Reference： [1]Chemical and Pharmaceutical Bulletin,1984,vol. 32,p. 967 - 976

32
[ 36236-76-7 ]
[ 64578-00-3 ]

Reference： [1]Chemical and Pharmaceutical Bulletin,1984,vol. 32,p. 967 - 976

33
[ 36236-76-7 ]
[ 91522-56-4 ]

Reference： [1]Chemical and Pharmaceutical Bulletin,1984,vol. 32,p. 967 - 976

34
[ 36236-76-7 ]
7-(2,2-Dimethyl-[1,3]dioxolan-4-ylmethoxy)-1,3-dihydro-imidazo[4,5-b]quinolin-2-one [ No CAS ]

Reference： [1]Journal of Medicinal Chemistry,1992,vol. 35,p. 2672 - 2687

35
[ 36236-76-7 ]
[ 142103-85-3 ]

Reference： [1]Journal of Medicinal Chemistry,1992,vol. 35,p. 2672 - 2687

36
[ 36236-76-7 ]
7-(2,2-Dimethyl-[1,3]dioxolan-4-ylmethoxy)-1,3,9,9a-tetrahydro-imidazo[4,5-b]quinolin-2-one [ No CAS ]

Reference： [1]Journal of Medicinal Chemistry,1992,vol. 35,p. 2672 - 2687

37
[ 36236-76-7 ]
5-[1-[5-(2,2-Dimethyl-[1,3]dioxolan-4-ylmethoxy)-2-nitro-phenyl]-meth-(Z)-ylidene]-imidazolidine-2,4-dione [ No CAS ]

Reference： [1]Journal of Medicinal Chemistry,1992,vol. 35,p. 2672 - 2687

38
[ 36236-76-7 ]
[ 84508-72-5 ]
[ 595568-01-7 ]

Yield	Reaction Conditions	Operation in experiment
	With potassium carbonate; In acetonitrile;	Production of Bis-(2,2-dimethyl)-[1,3]dioxolan-4-yl-methyl)-amine: [0065] 152.21 g (1.10 mol) of potassium carbonate and 142.88 g (0.73 mol) of 4-bromomethyl-2,2-dimethyl-1,3-dioxolane were added to a solution of 243.16 g (1.10 mol) of 1-N-benzylamino-2,3-O-isopropylidine glycerol (production: Synthesis, 627, 1995) in 600 ml of acetonitrile, and it was refluxed for 10 hours. After filtration, it was concentrated by evaporation in a vacuum, and the crude product was purified by chromatography on a silica gel column (ethyl acetate/hexane 1:1+0.5% triethylamine). The yield of bis-(2,2-dimethyl)-[1,3]dioxolan-4-yl-methyl)-benzylamine was 179.98 g. TLC Rf 0.73 (CH2Cl2/MeOH 10:1). [0066] 1H-NMR (CDCl3): δ (ppm) 1.36 [s, 6H, O2 (CH3)2], 1.44 [s, 6H, O2(CH3)2], 2.74 [d, 4H, N(CH2CHR)2], 3.67 [dd, 2H, CHCH2O], 3.83 [s, 2H, CbenzylH2], 4.04 [dd, 2H, CHCH2O], 4.26 [m, 2H, CH(O)CH2O], 7.29 [m, 5H, ArH][0067] MS (Cl): m/z (%) 336 (100) [M+H]+, 91 (4) [Benzyl]+

Reference： [1]Patent: US2003/236407,2003,A1 .Location in patent: Page 4

39
[ 292144-08-2 ]
[ 36236-76-7 ]
[ 672326-03-3 ]

Yield	Reaction Conditions	Operation in experiment
	With caesium carbonate; In DMF (N,N-dimethyl-formamide); at 100℃; for 17h;	Cesium carbonate (3.91 g) is added to a solution [OF N-(4-CHLOROBENZYL)-4-HYDROXY-2-] (hydroxymethyl) [THIENO [2, 3-B] PYRIDINE-5-CARBOXAMIDE] (3.49 g, prepared as described in US [6, 239,] 142) and [4- (BROMOMETHYL)-2, 2-DIMETHYL-1,] 3-dioxolane (1.95 g) in DMF (20 [ML). THE] reaction mixture is stirred at [100 C] for 17 h. The solvent is evaporated and the residue is dissolved in 10% CH30H in CH2Cl2. The mixture is washed with water and the organic layer is dried (MgSO4), filtered, and concentrated. The crude product is crystallized from EtOAc to afford 2.7 g of the title compound as a white solid. Physical characteristics. 1H NMR (400 [MHZ,] DMSO-d6) 8 10.53, 8.70, 7.40, 7.34, 7.28, 5.79, 4.69, 4.53, 4.50, 4.30, 4.14, 3.77, 1. [34,] 1.23 ; MS (EI) m/z 462 [(M)] ; HRMS (FAB) m/z 463. 1087 [(M+H) +.] Anal. Found: C, 57.07 ; H, 5. [01] ; N, 6.05.
	With caesium carbonate; In DMF (N,N-dimethyl-formamide); at 100℃; for 17h;	Cesium carbonate (3.91 g) is added to a solution [OF N- (4-CHLOROBENZYL)-4-HYDROXY-2-] (hydroxymethyl) thieno [2, [3-B]] [PYRIDINE-5-CARBOXAMIDE] (3.49 g, prepared as described in US 6,239, 142) and 4-(bromomethyl)-2,2-dimethyl-1, 3-dioxolane (1.95 g) in DMF (20 mL). The reaction mixture is stirred at [100 C] for 17 h. The solvent is evaporated and the redisue is dissolved in 10% CH30H in [CH2C12.] The mixture is washed with water and the organic layer is dried (MgSO4), filtered, and concentrated. The crude product is crystallized from EtOAc to afford 2.7 g of the title compound as a white solid. Physical characteristics. 1H NMR (400 [MHZ,] DMSO-d6) [8] 10.53, 8.70, 7.40, 7.34, 7.28, 5. [79,] 4.69, 4. [53,] 4.50, 4. [30,] 4. [14,] 3. [77,] 1.34, 1.23 ; MS [(EI)] [M/Z] 462 [(M)] ; HRMS [(FAB)] m/z 463.1087 [(M+H) +.] Anal. Found : C, 57.07 ; H, 5.01 ; N, 6. 05.
	With cesium carbonate; In DMF (N,N-dimethyl-formamide); at 100℃; for 17h;	Cesium carbonate (3.91 g) is added to a solution of N-(4-chlorobenzyl)-4-hydroxy-2- (hydroxymethyl) thieno [2, 3-B] pyridine-5-carboxamide (3.49 g, prepared as described in US 6,239, 142) AND 4- (BROMOMETHYL)-2, 2-DIMETHYL-1, 3-dioxolane (1.95 g) IN DMF (20 ML). The reaction mixture is stirred at 100 C for 17 h. The solvent is evaporated and the redisue is dissolved in 10% CH3OH in CH2Cl2. The mixture is washed with water and the organic layer is dried (MgSO4), filtered, and concentrated. The crude product is crystallized from EtOAc to afford 2.7 g of the title compound as a white solid. Physical characteristics. 1H NMR (400 MHz, DMSO-d6) 8 10.53, 8.70, 7.40, 7.34, 7.28, 5.79, 4.69, 4.53, 4. 50, 4.30, 4.14, 3.77, 1.34, 1.23 ; MS (EI) m/z 462 (M+) ; HRMS (FAB) m/z 463.1087 (M+H) +. Anal. Found : C, 57.07 ; H, 5.01 ; N, 6.05.

Reference： [1]Patent: WO2004/22567,2004,A1 .Location in patent: Page 30
[2]Patent: WO2004/22568,2004,A1 .Location in patent: Page 29
[3]Patent: WO2004/106345,2004,A2 .Location in patent: Page 32

40
[ 4704-77-2 ]
[ 584-08-7 ]
[ 36236-76-7 ]

Yield	Reaction Conditions	Operation in experiment
19.1 grams (53.5%)	With sulfuric acid; In acetone;	EXAMPLE 21 (+-)-N-(2,2-Dimethyl-1,3-dioxolan-4-yl)methyl-N,N-dimethyl-β-hydroxyethyl ammonium bromide Into a 500 milliliter round bottom flask equipped with a magnetic stir bar and drying tube, a solution of 28.0 grams (0.181 mole) of 3-bromo-1,2-propanediol in 200 milliliters of acetone was added. Then, 0.5 milliliter of concentrated sulfuric acid was added and the reaction allowed to proceed at room temperature for 24 hours with continuous stirring. The reaction mixture was neutralized with 13.0 grams of K2 CO3 for 30 minutes, the solution was filtered and the solvent evaporated in vacuo. The resulting oil was dissolved in 150 milliliter of ether, extracted three times with 150 milliliter portions of water and the organic layer dried over anhydrous sodium sulfate. The filtered ether was evaporated in vacuo and 100 milliliters of hexanes was added, resulting in two layers. The upper layer was decanted and evaporated in vacuo to provide 19.1 grams (53.5%) of (2,2-dimethyl-1,3-dioxolan-4-yl)methyl bromide.

Reference： [1]Patent: US5614548,1997,A

41
[ 36236-76-7 ]
[ 917460-80-1 ]
[ 1019877-86-1 ]
[ 1019877-80-5 ]

Reference： [1]Bioorganic and Medicinal Chemistry Letters,2008,vol. 18,p. 1431 - 1435

42
[ 36236-76-7 ]
[ 1019877-98-5 ]
[ 1019878-04-6 ]
[ 1019878-11-5 ]

Reference： [1]Bioorganic and Medicinal Chemistry Letters,2008,vol. 18,p. 1431 - 1435

43
[ 36236-76-7 ]
[ 85999-40-2 ]
[ 1082746-58-4 ]

Yield	Reaction Conditions	Operation in experiment
		Example 28: Synthesis of 3,28-dihydroxy-20(29)-lupen-28-oic acid, 2,2-dimethyl-l,3- dioxolane-4yl-methylester (DA038); [0186] To a solution of 3,23-dihydroxy-20(29)-lupen-28-oic acid (150 mg, 0.32 mmol) in 2 mL DMF, was added sodium hydroxide (25 mg, 0.64 mmol). After the resulting mixture was stirred at room temperature for 15 min, 4-(bromomethyl)-2,2-dimethyl-l,3-dioxolane (310 mg, 1.6 mmol) was added. The reaction was stirred at 60 degree overnight. After TLC showed the reaction was complete, the mixture was diluted with water and extracted with ethyl acetate (60 mL x 3). The combined ethyl acetate layer was washed with 5% HCl (5 mL x 1), saturated sodium bicarbonate (5 mL x 1), water (5 mL x 1), brine (5 mL x 1) and dried over sodium sulfate. Purification by column chromatography on silica gel gave the desired product as a white solid.

Reference： [1]Patent: WO2008/138200,2008,A1 .Location in patent: Page/Page column 53

44
[ 36236-76-7 ]
[ 953425-38-2 ]
[ 1038914-88-3 ]

Reference： [1]Journal of Medicinal Chemistry,2008,vol. 51,p. 3814 - 3824

45
[ 34832-91-2 ]
[ 36236-76-7 ]

Reference： [1]Russian Journal of General Chemistry,2008,vol. 78,p. 2407 - 2408

46
[ 36236-76-7 ]
[ 51-17-2 ]
[ 804550-95-6 ]

Reference： [1]Synthetic Communications,2010,vol. 40,p. 2578 - 2587

47
[ 36236-76-7 ]
[ 1313409-30-1 ]
[ 1313409-36-7 ]
[ 1313409-34-5 ]

Yield	Reaction Conditions	Operation in experiment
	With caesium hydroxide hydrate; In N,N-dimethyl-formamide; at 20℃; for 16h;	To a solution of N-(l-((lH-pyrazol-3-yl)methyl)-3-ethyl-lH-indazol-4-yl)imidazo[l,2-a]pyridine- 3-carboxamide (40 mg, 0.104 mmol) in N,N-dimethylformamide (0.5 mL) was added 4- (bromomethyl)-2,2-dimethyl-l,3-dioxolane (20.2 mg, 0.104 mmol) and cesium hydroxide hydrate (17.4 mg, 0.104 mmol). The mixture was stirred for 16 hours at ambient temperature, filtered, washing with methanol and ethyl acetate, and concentrated under a stream of nitrogen. The resulting material was purified using preparative thin layer chromatography on silica, eluting with 10% methanol in dichloromethane. The isolated product (22.5 mg) was a 7:3 mixture of two regioisomers, N-(l-((l-((2,2-dimethyl-l,3-dioxolan-4-yl)methyl)-lH- pyrazol-5-yl)methyl)-3-ethyl-lH-indazol-4-yl)imidazo[l,2-a]pyridine-3-carboxamide and N- (1 -((1 -(2,3-dihydroxypropyl)- lH-pyrazol-3-yl)methyl)-3-ethyl- lH-indazol-4-yl)imidazo[ 1 ,2- a]pyridine-3-carboxamide. This material was continued to the next step as a mixture.

Reference： [1]Patent: WO2011/79076,2011,A1 .Location in patent: Page/Page column 87

48
[ 36236-76-7 ]
[ 269410-08-4 ]
[ 1326714-01-5 ]

Yield	Reaction Conditions	Operation in experiment
63%	With caesium carbonate; In N,N-dimethyl-formamide; at 20℃;	To a solution of 4- (4, 4, 5, 5-tetramethyl-1, 3, 2-dioxaborolan-2-yl) -1H-pyrazole (500 mg, 2.57 mmol) and 4- (bromomethyl) -2, 2-dimethyl-1, 3-dioxolane (501 mg, 2.57 mmol) in DMF (10 mL) was added Cs2CO3, DMF, 0C (1.25 g, 3.85 mmol) . The reaction mixture was stirred at RT overnight. The solution was filtered and concentrated to give the desired compound (500 mg, 63 ) as a yellow oil. LCMS (ESI) m/z 309 [M+H]+.

Reference： [1]Patent: WO2015/196759,2015,A1 .Location in patent: Paragraph 00370; 00371

49
[ 36236-76-7 ]
N-tert-butyl-1-(3,5-dichlorophenyl)-8-(1-((2,2-dimethyl-1,3-dioxolan-4-yl)methyl)-1H-pyrazol-4-yl)-7-methoxy-N-methyl-1,4-dihydrochromeno[4,3-c]pyrazole-3-carboxamide [ No CAS ]

Reference： [1]Patent: WO2015/196759,2015,A1

50
[ 36236-76-7 ]
[ 100-46-9 ]
[ 84508-72-5 ]

Reference： [1]Journal of Organic Chemistry,2017,vol. 82,p. 6748 - 6763

51
[ 36236-76-7 ]
[ 100-46-9 ]
C₂₂H₂₉NO₇ [ No CAS ]

Reference： [1]Journal of Organic Chemistry,2017,vol. 82,p. 6748 - 6763

52
[ 36236-76-7 ]
[ 749927-95-5 ]
1-(2,2-dimethyl-1,3-dioxolan-4-yl)-4-(4-methoxyphenyl)butan-2-one [ No CAS ]

Reference： [1]Angewandte Chemie - International Edition,2017,vol. 56,p. 10791 - 10795
Angew. Chem.,2017,vol. 129,p. 10931 - 10935

53
[ 36236-76-7 ]
[ 672326-05-5 ]

Reference： [1]Patent: WO2004/106345,2004,A2

54
[ 36236-76-7 ]
[ 804511-32-8 ]

Reference： [1]Patent: WO2004/106345,2004,A2

55
[ 36236-76-7 ]
[ 804511-26-0 ]

Reference： [1]Patent: WO2004/106345,2004,A2

56
[ 36236-76-7 ]
ethyl 6-(tert-butyl)-10-hydroxy-2-oxo-6,7-dihydro-2H-pyrido[2’,1‘:3,4]pyrazino[1,2-b]indazole-3-carboxylate [ No CAS ]
ethyl 6-(tert-butyl)-10-((2,2-dimethyl-1,3-dioxolan-4-yl)methoxy)-2-oxo-6,7-dihydro-2H-pyrido[2’,1‘:3,4]pyrazino[1,2-b]indazole-3-carboxylate [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
		10513] To 2.lh (18 mg, 0.047 mmol) was added DMF (Volume: 0.5 mE) and cesium carbonate (53.8 mg, 0.165 mmol). The reaction was stirred at room temperature for 5 minutes then 4-(bromomethyl)-2,2-dimethyl-1 ,3-dioxolane (23.01 mg, 0.118 mmol) added. The reaction was heated to 70 C. and stirred for 3 hours or until done by ECMS. The reaction was cooled, 0.5 ml of DMF was added, then filtered through a 0.45 nM in line filtet The DMF solution with the desired product 2.28a was used as is for the next step, assume quantitative yield. LC-MS (mlz): 496.4 [M+H],0.84 min

Reference： [1]Patent: US2018/312507,2018,A1 .Location in patent: Paragraph 0512; 0513

57
[ 36236-76-7 ]
1-[(R)-1-(2-fluoro-6-methylphenyl)pyrrolidin-3-yl]-4-hydroxy-3-(2-trifluoromethylbenzyl)-1,3-dihydrobenzoimidazol-2-one [ No CAS ]
4-(2,2-dimethyl-[1,3]dioxolan-4-ylmethoxy)-1-[(R)-1-(2-fluoro-6-methylphenyl)pyrrolidin-3-yl]-3-(2-trifluoromethylbenzyl)-1,3-dihydrobenzoimidazol-2-one [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	With potassium carbonate; In dimethyl sulfoxide; at 80 - 100℃; for 19.5h;	General procedure: To a stirred soln. of Ij (1 eq) in DMSO (10 mL/mmol) was added K2CO3 (2 eq) followed by the corresponding halide (1.1 eq). The rxn mixture was stirred at a given temperature for a given time (see Table 34). It was partitioned between EtOAc and H2O. The org. phase was washed with water (3x) and brine, dried over MgSC>4 and concentrated in vacuo. The crude was purified by CC using Hept/EtOAc or by prep. LC-MS using method 3.

Reference： [1]Patent: WO2019/141803,2019,A1 .Location in patent: Page/Page column 125

58
[ 36236-76-7 ]
[ 19792-91-7 ]
phenyl (4-(bromomethyl)-2,2-dimethyl-1,3-dioxolan-4-yl)sulfamate [ No CAS ]

Reference： [1]Organic Letters,2020,vol. 22,p. 1687 - 1691

59
[ 36236-76-7 ]
[ 19792-91-7 ]
phenyl 5,5-dimethyl-4,6-dioxa-1-azaspiro[2.4]heptane-1-sulfonate [ No CAS ]

Reference： [1]Organic Letters,2020,vol. 22,p. 1687 - 1691

60
[ 36236-76-7 ]
C₈H₇N₃O₃ [ No CAS ]
methyl 2-azido-4-[(2,2-dimethyl-1,3-dioxolan-4-yl)methoxy]benzoate [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
71%	With potassium carbonate; In N,N-dimethyl-formamide; at 50℃; for 96h;	To a solution of Intermediate 11-12 (75 mg, 0.39 mmol) in DMF (1 mL), 4- (bromomethyl)-2, 2-dimethyl- 1,3-dioxo lane (66 uL, 0.47 mmol), and K2CO3 (215 mg, 1.55 mmol) were added and the reaction mixture was stirred at 50C for 4 days. The reaction mixture was diluted with EtOAc (150 mL), washed with sat. NH4C1 solution and brine, dried over Na2S04, filtered and evaporated under vacuum to yield the title product (85 mg, 71 %).

Reference： [1]Patent: WO2020/109350,2020,A1 .Location in patent: Page/Page column 87

61
[ 36236-76-7 ]
C₁₃H₁₅N₃O₅ [ No CAS ]

Reference： [1]Patent: US2020/231605,2020,A1

62
[ 36236-76-7 ]
[ 123-31-9 ]
[ 137275-78-6 ]

Yield	Reaction Conditions	Operation in experiment
12%	With potassium hydroxide; In dimethyl sulfoxide; at 20℃; for 72h;	KOH (40.27 g, 717.7 mmol, 20 eq.) is introduced into a hydroquinone solution (11.85 g, 107.7 mmol, 3 eq.) in 150 mL of dimethylsulphoxide (DMSO). Compound B1 (7.00 g, 35.89 mmol, 1 eq.) is then added dropwise at room temperature to the reaction mixture. After 3 days of stirring at room temperature, the reaction is neutralised by adding ammonium bicarbonate. Water is added to the reaction mixture which is then extracted with chloroform. The organic phases are combined, washed with water before being dried over MgSO4. The solvent is evaporated under vacuum and the crude reaction product is purified by silica column chromatography using chloroform then ether as eluents. Compound B2 (0.94 g, yield=12%) is thus obtained in the form of a colourless liquid. 1H NMR (DMSO-d6, 400 MHz): δ (ppm): 8.91 (s, 1H), 6.76 (m, 2H), 6.66 (m, 2H), 4.34 (m, 1H), 4.06 (dd, 1H, J=8.3 Hz, J=6.6 Hz), 3.87 (m, 2H), 3.71 (dd, 1H, J=8.3 Hz, J=6.3 Hz), 1.34 (s, 3H), 1.29 (s, 3H).

Reference： [1]Patent: US2020/231605,2020,A1 .Location in patent: Paragraph 0310-0312

Same Skeleton Products

Related Products

Historical Records

Related Functional Groups of
[ 36236-76-7 ]

Bromides

[ 18742-02-4 ]

2-(2-Bromoethyl)-1,3-dioxolane

Similarity: 0.74

[ 126-38-5 ]

1-Bromo-2,2-dimethoxypropane

Similarity: 0.74

[ 22094-18-4 ]

1,3-Dibromo-2,2-dimethoxypropane

Similarity: 0.72

[ 4360-63-8 ]

2-Bromomethyl-1,3-dioxolane

Similarity: 0.68

[ 3400-55-3 ]

2-Bromopriopionaldehydediethylacetal

Similarity: 0.62

Related Parent Nucleus of
[ 36236-76-7 ]

Dioxolanes

[ 18742-02-4 ]

2-(2-Bromoethyl)-1,3-dioxolane

Similarity: 0.74

[ 22323-82-6 ]

(S)-(+)-2,2-Dimethyl-1,3-dioxolane-4-methanol

Similarity: 0.71

[ 14347-78-5 ]

(R)-(2,2-Dimethyl-1,3-dioxolan-4-yl)methanol

Similarity: 0.71

[ 1607-37-0 ]

4-[(2,3-Epoxypropoxy)methyl]-2,2-dimethyl-1,3-dioxolane

Similarity: 0.69

[ 4360-63-8 ]

2-Bromomethyl-1,3-dioxolane

Similarity: 0.68

Ghs Precautionary Statements

Precautionary Statements-General
Code	Phrase
P101	If medical advice is needed,have product container or label at hand.
P102	Keep out of reach of children.
P103	Read label before use
Prevention
Code	Phrase
P201	Obtain special instructions before use.
P202	Do not handle until all safety precautions have been read and understood.
P210	Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
P211	Do not spray on an open flame or other ignition source.
P220	Keep/Store away from clothing/combustible materials.
P221	Take any precaution to avoid mixing with combustibles
P222	Do not allow contact with air.
P223	Keep away from any possible contact with water, because of violent reaction and possible flash fire.
P230	Keep wetted
P231	Handle under inert gas.
P232	Protect from moisture.
P233	Keep container tightly closed.
P234	Keep only in original container.
P235	Keep cool
P240	Ground/bond container and receiving equipment.
P241	Use explosion-proof electrical/ventilating/lighting/equipment.
P242	Use only non-sparking tools.
P243	Take precautionary measures against static discharge.
P244	Keep reduction valves free from grease and oil.
P250	Do not subject to grinding/shock/friction.
P251	Pressurized container: Do not pierce or burn, even after use.
P260	Do not breathe dust/fume/gas/mist/vapours/spray.
P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P262	Do not get in eyes, on skin, or on clothing.
P263	Avoid contact during pregnancy/while nursing.
P264	Wash hands thoroughly after handling.
P265	Wash skin thouroughly after handling.
P270	Do not eat, drink or smoke when using this product.
P271	Use only outdoors or in a well-ventilated area.
P272	Contaminated work clothing should not be allowed out of the workplace.
P273	Avoid release to the environment.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P281	Use personal protective equipment as required.
P282	Wear cold insulating gloves/face shield/eye protection.
P283	Wear fire/flame resistant/retardant clothing.
P284	Wear respiratory protection.
P285	In case of inadequate ventilation wear respiratory protection.
P231 + P232	Handle under inert gas. Protect from moisture.
P235 + P410	Keep cool. Protect from sunlight.
Response
Code	Phrase
P301	IF SWALLOWED:
P304	IF INHALED:
P305	IF IN EYES:
P306	IF ON CLOTHING:
P307	IF exposed:
P308	IF exposed or concerned:
P309	IF exposed or if you feel unwell:
P310	Immediately call a POISON CENTER or doctor/physician.
P311	Call a POISON CENTER or doctor/physician.
P312	Call a POISON CENTER or doctor/physician if you feel unwell.
P313	Get medical advice/attention.
P314	Get medical advice/attention if you feel unwell.
P315	Get immediate medical advice/attention.
P320
P302 + P352	IF ON SKIN: wash with plenty of soap and water.
P321
P322
P330	Rinse mouth.
P331	Do NOT induce vomiting.
P332	IF SKIN irritation occurs:
P333	If skin irritation or rash occurs:
P334	Immerse in cool water/wrap n wet bandages.
P335	Brush off loose particles from skin.
P336	Thaw frosted parts with lukewarm water. Do not rub affected area.
P337	If eye irritation persists:
P338	Remove contact lenses, if present and easy to do. Continue rinsing.
P340	Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P341	If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P342	If experiencing respiratory symptoms:
P350	Gently wash with plenty of soap and water.
P351	Rinse cautiously with water for several minutes.
P352	Wash with plenty of soap and water.
P353	Rinse skin with water/shower.
P360	Rinse immediately contaminated clothing and skin with plenty of water before removing clothes.
P361	Remove/Take off immediately all contaminated clothing.
P362	Take off contaminated clothing and wash before reuse.
P363	Wash contaminated clothing before reuse.
P370	In case of fire:
P371	In case of major fire and large quantities:
P372	Explosion risk in case of fire.
P373	DO NOT fight fire when fire reaches explosives.
P374	Fight fire with normal precautions from a reasonable distance.
P376	Stop leak if safe to do so. Oxidising gases (section 2.4) 1
P377	Leaking gas fire: Do not extinguish, unless leak can be stopped safely.
P378
P380	Evacuate area.
P381	Eliminate all ignition sources if safe to do so.
P390	Absorb spillage to prevent material damage.
P391	Collect spillage. Hazardous to the aquatic environment
P301 + P310	IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P301 + P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P301 + P330 + P331	IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P302 + P334	IF ON SKIN: Immerse in cool water/wrap in wet bandages.
P302 + P350	IF ON SKIN: Gently wash with plenty of soap and water.
P303 + P361 + P353	IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304 + P312	IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell.
P304 + P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P304 + P341	IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P306 + P360	IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes.
P307 + P311	IF exposed: call a POISON CENTER or doctor/physician.
P308 + P313	IF exposed or concerned: Get medical advice/attention.
P309 + P311	IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician.
P332 + P313	IF SKIN irritation occurs: Get medical advice/attention.
P333 + P313	IF SKIN irritation or rash occurs: Get medical advice/attention.
P335 + P334	Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages.
P337 + P313	IF eye irritation persists: Get medical advice/attention.
P342 + P311	IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P370 + P376	In case of fire: Stop leak if safe to Do so.
P370 + P378	In case of fire:
P370 + P380	In case of fire: Evacuate area.
P370 + P380 + P375	In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion.
P371 + P380 + P375	In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion.
Storage
Code	Phrase
P401
P402	Store in a dry place.
P403	Store in a well-ventilated place.
P404	Store in a closed container.
P405	Store locked up.
P406	Store in corrosive resistant/ container with a resistant inner liner.
P407	Maintain air gap between stacks/pallets.
P410	Protect from sunlight.
P411
P412	Do not expose to temperatures exceeding 50 oC/ 122 oF.
P413
P420	Store away from other materials.
P422
P402 + P404	Store in a dry place. Store in a closed container.
P403 + P233	Store in a well-ventilated place. Keep container tightly closed.
P403 + P235	Store in a well-ventilated place. Keep cool.
P410 + P403	Protect from sunlight. Store in a well-ventilated place.
P410 + P412	Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF.
P411 + P235	Keep cool.
Disposal
Code	Phrase
P501	Dispose of contents/container to ...
P502	Refer to manufacturer/supplier for information on recovery/recycling

Purity	Size	Price	VIP Price	USA Stock *0-1 Day	Global Stock *5-7 Days	Quantity
{[ item.p_purity ]}	{[ item.pr_size ]}	{[ getRatePrice(item.pr_usd, 1,1) ]} {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate) ]}	{[ getRatePrice(item.pr_usd, 1,1) ]}	Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate) ]} {[ getRatePrice(item.pr_usd,1,item.mem_rate) ]}	{[ item.pr_usastock ]}	Inquiry -	{[ item.pr_chinastock ]}	Inquiry -

Physical hazards
Code	Phrase
H200	Unstable explosive
H201	Explosive; mass explosion hazard
H202	Explosive; severe projection hazard
H203	Explosive; fire, blast or projection hazard
H204	Fire or projection hazard
H205	May mass explode in fire
H220	Extremely flammable gas
H221	Flammable gas
H222	Extremely flammable aerosol
H223	Flammable aerosol
H224	Extremely flammable liquid and vapour
H225	Highly flammable liquid and vapour
H226	Flammable liquid and vapour
H227	Combustible liquid
H228	Flammable solid
H229	Pressurized container: may burst if heated
H230	May react explosively even in the absence of air
H231	May react explosively even in the absence of air at elevated pressure and/or temperature
H240	Heating may cause an explosion
H241	Heating may cause a fire or explosion
H242	Heating may cause a fire
H250	Catches fire spontaneously if exposed to air
H251	Self-heating; may catch fire
H252	Self-heating in large quantities; may catch fire
H260	In contact with water releases flammable gases which may ignite spontaneously
H261	In contact with water releases flammable gas
H270	May cause or intensify fire; oxidizer
H271	May cause fire or explosion; strong oxidizer
H272	May intensify fire; oxidizer
H280	Contains gas under pressure; may explode if heated
H281	Contains refrigerated gas; may cause cryogenic burns or injury
H290	May be corrosive to metals
Health hazards
Code	Phrase
H300	Fatal if swallowed
H301	Toxic if swallowed
H302	Harmful if swallowed
H303	May be harmful if swallowed
H304	May be fatal if swallowed and enters airways
H305	May be harmful if swallowed and enters airways
H310	Fatal in contact with skin
H311	Toxic in contact with skin
H312	Harmful in contact with skin
H313	May be harmful in contact with skin
H314	Causes severe skin burns and eye damage
H315	Causes skin irritation
H316	Causes mild skin irritation
H317	May cause an allergic skin reaction
H318	Causes serious eye damage
H319	Causes serious eye irritation
H320	Causes eye irritation
H330	Fatal if inhaled
H331	Toxic if inhaled
H332	Harmful if inhaled
H333	May be harmful if inhaled
H334	May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335	May cause respiratory irritation
H336	May cause drowsiness or dizziness
H340	May cause genetic defects
H341	Suspected of causing genetic defects
H350	May cause cancer
H351	Suspected of causing cancer
H360	May damage fertility or the unborn child
H361	Suspected of damaging fertility or the unborn child
H361d	Suspected of damaging the unborn child
H362	May cause harm to breast-fed children
H370	Causes damage to organs
H371	May cause damage to organs
H372	Causes damage to organs through prolonged or repeated exposure
H373	May cause damage to organs through prolonged or repeated exposure
Environmental hazards
Code	Phrase
H400	Very toxic to aquatic life
H401	Toxic to aquatic life
H402	Harmful to aquatic life
H410	Very toxic to aquatic life with long-lasting effects
H411	Toxic to aquatic life with long-lasting effects
H412	Harmful to aquatic life with long-lasting effects
H413	May cause long-lasting harmful effects to aquatic life
H420	Harms public health and the environment by destroying ozone in the upper atmosphere

[ CAS No. 36236-76-7 ] {[proInfo.proName]}

Quality Control of [ 36236-76-7 ]

Related Doc. of [ 36236-76-7 ]

Product Details of [ 36236-76-7 ]

Safety of [ 36236-76-7 ]

Application In Synthesis of [ 36236-76-7 ]

[ 36236-76-7 ] Synthesis Path-Upstream 1~6

[ 36236-76-7 ] Synthesis Path-Downstream 1~62

Related Functional Groups of [ 36236-76-7 ]

Bromides

Related Parent Nucleus of [ 36236-76-7 ]

Dioxolanes

Precautionary Statements-General

Prevention

Response

Storage

Disposal

Physical hazards

Health hazards

Environmental hazards

Inquiry

Related Functional Groups of
[ 36236-76-7 ]

Related Parent Nucleus of
[ 36236-76-7 ]