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Chemical Structure| 366-47-2 Chemical Structure| 366-47-2

Structure of 366-47-2

Chemical Structure| 366-47-2

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Product Details of [ 366-47-2 ]

CAS No. :366-47-2
Formula : C9H8FNO3
M.W : 197.16
SMILES Code : O=C(O)CNC(C1=CC=CC(F)=C1)=O
MDL No. :MFCD00479174

Safety of [ 366-47-2 ]

Application In Synthesis of [ 366-47-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 366-47-2 ]

[ 366-47-2 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 366-47-2 ]
  • [ 34595-26-1 ]
  • [ 1447964-08-0 ]
YieldReaction ConditionsOperation in experiment
46% With sodium acetate; acetic anhydride; In neat (no solvent); at 95℃; General procedure: A mixture of <strong>[34595-26-1]2-(piperidin-1-yl)benzaldehyde</strong> (0.946 g, 5 mmol) and 2-benzamidoacetic acid (0.896 g, 5 mmol) was heated in 95 C with the addition of NaOAc (2.5 mmol) and Ac2O (5 mmol). After completion of the reaction, 2 mL ethanol was added to the mixture and was stirred for 10 h at room temperature. The solid was filtered off, washed with water, and ice-cold ethanol. The crude product was recrystallized from toluene to give the corresponding (Z)-alkylidene azlactones 1a (Note: For the preparation of compounds 1b-n, the corresponding crude products were recrystallized from ethanol to give the desired products 1b-n).
  • 2
  • [ 366-47-2 ]
  • [ 34595-26-1 ]
  • 2-(3-fluorophenyl)-1',2',3',4',4a',6'-hexahydro-5H-spiro[oxazole-4,5'-pyrido[1,2-a]quinolin]-5-one [ No CAS ]
  • 2-(3-fluorophenyl)-1',2',3',4',4a',6'-hexahydro-5H-spiro[oxazole-4,5'-pyrido[1,2-a]quinolin]-5-one [ No CAS ]
 

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