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Chemical Structure| 36617-02-4 Chemical Structure| 36617-02-4

Structure of 36617-02-4

Chemical Structure| 36617-02-4

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Product Details of [ 36617-02-4 ]

CAS No. :36617-02-4
Formula : C9H9Br
M.W : 197.07
SMILES Code : BrC1C(C2=CC=CC=C2)C1
MDL No. :MFCD00760308

Safety of [ 36617-02-4 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

Application In Synthesis of [ 36617-02-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 36617-02-4 ]

[ 36617-02-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 124-38-9 ]
  • [ 36617-02-4 ]
  • [ 939-89-9 ]
  • [ 939-90-2 ]
YieldReaction ConditionsOperation in experiment
With nickel(II) bromide dimethoxyethane; manganese; lithium chloride; 2,9-di-n-hexyl-1,10-phenanthroline; In N,N-dimethyl acetamide; at 30℃; under 760.051 Torr; for 48h;Schlenk technique; General procedure: An oven-dried Schlenk tube containing a stirring bar was charged with NiBr2·glyme (0.02 mmol, 10 molpercent), L3 (0.05 mmol, 26 molpercent), Mn (0.52 mmol, 2.60 equiv) and LiCl (0.80 mmol, 4 equiv). The Schlenk tube was evacuated and backfilled under CO2 flow (this procedure was repeated three times). Anhydrous DMA (0.50 mL) and the corresponding cyclopropyl bromide 1 (0.20 mmol, 1 equiv) were then added under CO2 flow. The Schlenk tube was next closed at atmospheric pressure of CO2 (1 atm) and the mixture was stirred for 48 h. The mixture was then carefully quenched with 2M HCl to hydrolyze the resulting carboxylate, and extracted several times with EtOAc and CH2Cl2. The combined organic layers were dried over MgSO4 and concentrated under reduced pressure. The products were purified by flash chromatography (hexanes?EtOAc).
 

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