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Chemical Structure| 36640-52-5 Chemical Structure| 36640-52-5

Structure of 36640-52-5

Chemical Structure| 36640-52-5

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Product Details of [ 36640-52-5 ]

CAS No. :36640-52-5
Formula : C17H14N2O
M.W : 262.31
SMILES Code : O=CC1=CN(C2=CC=CC=C2)N=C1C3=CC=C(C)C=C3
MDL No. :MFCD00744772
InChI Key :PUUGVPPTLNTKIM-UHFFFAOYSA-N
Pubchem ID :689801

Safety of [ 36640-52-5 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Application In Synthesis of [ 36640-52-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 36640-52-5 ]

[ 36640-52-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 3528-17-4 ]
  • [ 17356-08-0 ]
  • [ 36640-52-5 ]
  • 4-(1-phenyl-3-(p-tolyl)-1H-pyrazol-4-yl)-3,4-dihydro-1H-thiochromeno[4,3-d]pyrimidine-2(5H)-thione [ No CAS ]
YieldReaction ConditionsOperation in experiment
84% With 1-butyl-3-methylimidazolium hydrogen sulfate; at 70℃; for 2h;Green chemistry; General procedure: General procedure for the synthesis of thiochromeno[3,4-d]pyrimidine (4): A dry 50 mL flask was charged with thiochroman-4-one 1 (1 mmol), aromatic aldehyde 2 a-n (1 mmol), thiourea 3 and [Bmim]HSO4 ionic liquid (2 mL). The reaction mixture was stirred at 70 C for 1 h. The progress of the reaction was monitored by TLC (eluent = n-hexane/ethyl acetate: 8/2, v/v). After completion of the reaction, the reaction mixture was cooled to RT and poured into ice cold water, the solid separated was filtered, washed with water, dried and purified by column chromatography using silica gel (ethyl acetate/n-hexane: 2/8, v/v) to afford title compounds 4a-n in good yields.
 

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