Alternatived Products of [ 371975-46-1 ]
Product Details of [ 371975-46-1 ]
CAS No. : | 371975-46-1 |
MDL No. : | MFCD18910289 |
Formula : |
C12H21NO3
|
Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
227.30
|
Pubchem ID : | - |
Synonyms : |
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Safety of [ 371975-46-1 ]
Application In Synthesis of [ 371975-46-1 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 371975-46-1 ]
- 1
-
[ 371975-46-1 ]
-
[ 239073-93-9 ]
Yield | Reaction Conditions | Operation in experiment |
|
Multi-step reaction with 2 steps
1.1: NaH / tetrahydrofuran / 2 h / Heating
1.2: 89 percent / tetrahydrofuran / Heating
2.1: 96 percent / KIO4 / OsO4 / tetrahydrofuran; H2O / 20 °C |
|
- 2
-
[ 371975-46-1 ]
-
[ 1228450-21-2 ]
-
(R,S)-tert-butyl 2-methyl-1-oxa-6-azaspiro[2.5]octane-6-carboxylate
[ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
1: 73%
2: 9 %Spectr. |
Stage #1: 4-ethenyl-4-hydroxypiperidine-1-carboxylic acid 1,1-dimethylethyl ester With C44H54CoN2O2; 1-fluoro-2,4,6-trimethylpyridinium trifluoromethanesulfonate In acetone for 0.25h; Inert atmosphere; Sonication;
Stage #2: With methylphenylsilane In acetone at -40℃; for 2h; Inert atmosphere; |
|
1: 14 %Spectr.
2: 59% |
Stage #1: 4-ethenyl-4-hydroxypiperidine-1-carboxylic acid 1,1-dimethylethyl ester With 1,1,2,2-tetramethyl-1,2-ethanediamino-N,N'-bis(3,5-di-tert-butylsalicylidene)-cobalt(II); 1-fluoro-2,4,6-trimethylpyridinium trifluoromethanesulfonate In acetone for 0.25h; Inert atmosphere; Sonication;
Stage #2: With methylphenylsilane In acetone at 0℃; for 2h; Inert atmosphere; |
|
Reference:
[1]Touney, Eric E.; Foy, Nicholas J.; Pronin, Sergey V.
[Journal of the American Chemical Society, 2018, vol. 140, # 49, p. 16982 - 16987]
[2]Touney, Eric E.; Foy, Nicholas J.; Pronin, Sergey V.
[Journal of the American Chemical Society, 2018, vol. 140, # 49, p. 16982 - 16987]