630-580-1088 sales@ambeed.com
Structure Search

List Search MOL Search Structure Search

0
Chemistry
Asymmetric Synthesis >>Chiral Building BlocksChiral Catalysts, Chiral Ligands and Chiral ReagentsChiral Resolution ReagentsCatalysis Chemistry >>Achiral Crown LigandsC-H ActivationCarbon-Donor LigandsChiral Crown LigandsCross-CouplingCross-Coupling Using Transition Metal CatalystsDACH or Trost LigandsDiketone LigandsHydrogenationChemical Biology >>Conjugation ChemistryGlycoscienceLinkers and CrosslinkersNucleic Acid ChemistryPEGylation
Peptide ChemistryPhotolabile Protecting GroupHeterocyclic Building Blocks >>AcridinesAliphatic HeterocyclesAromatic HeterocyclesAzetidinesBenzimidazolesBenzisoxazolesBenzodioxansBenzofuransBenzothiazolesInorganic reagents >>Inorganic reagentOrganic Building Blocks >>Acyl ChloridesAlcoholsAldehydesAliphatic Chain HydrocarbonsAliphatic Cyclic Hydrocarbons
AlkenylsAlkylsAlkynylsAmidesOrganometallic Reagents >>Grignard ReagentsOrganoarsenicOrganobismuthOrganoboronOrganogermaniumOrganolithiumOrganomercuryOrganosiliconOrganotinSpecialty Synthesis >>Enzyme-Mediated SynthesisFluorous SynthesisIonic LiquidsSolid Supported SynthesisStains and Dyes >>
Acid DyesAzoic DyesBasic DyesDirect DyesDisperse DyesDye IntermediatesMordant DyesOil DyesOther Stains and DyesSynthetic Reagents >>Acids and BasesC-C Bond FormationC-X Bond Formation (Halogen)C-X Bond Formation (Non-Halogen)Chelation and Complexation CompoundsCondensation AgentsCouplingDehydrating ReagentsFluorination Reagent
Pharmaceutical Intermediates
Analgesics >>BenzhydrocodoneBicifadineCapsaicinCelecoxibDebio-0827DexamethasoneElagolix SodiumEsketamine HydrochlorideIbuprofen sodiumAnesthetics >>CiprofolEsketamine HydrochlorideFospropofol Fospropofol DisodiumLevobupivacaine RemimazolamRemimazolam BesilateRemimazolam besylateRopivacaineAnti-Addiction Agents >>Kakonein
Lofexidine HydrochlorideVarenicline Anti-inflammatory Agents >>ApremilastAsunaprevirATB-346 RelatedBalsalazide BaricitinibBencycloquidium BromideBudesonideCefiderocol Sulfate TosylateCeftaroline Fosamil AcetateAntibacterials >>AFN-1252 RelatedAlatrofloxacin Bedaquiline FumarateBesifloxacin BrilacidinCaspofungin AcetateCefiderocol Sulfate TosylateCefilavancinCeftaroline Fosamil
Anticonvulsants >>BrivaracetamCannabidiolEscitalopram OxalateEslicarbazepine Acetate RelatedFosphenytoinGabapentin EnacarbilJNJ-10234094LacosamideLevetiracetam RelatedAntidementia Agents >>Azeliragon RelatedDavunetideDonepezil HydrochlorideDonepezil RelatedEnsaculinFlorbetaben Flortaucipir F 18Flutemetamol IdalopirdineAntidepressants >>4-Chlorokynurenine
AgomelatineAgomelatine RelatedAllopregnanolone RelatedAmibegronAmitifadineAripiprazole RelatedBasimglurantBefloxatoneAntiemetics >>AprepitantAprepitant RelatedDolasetron RelatedDolasetron Mesylate HydrateFosaprepitant DimeglumineFosaprepitant RelatedOlanzapinePalonosetron RelatedPalonosetron HydrochlorideAntifungals >>Anidulafungin RelatedCabotegravirMore >>
Inhibitors/Agonists
ADC >>ADC LinkerADC Linker with PayloadADC ToxinAnti-infection >>3CLproAntibacterialAntifungalAntiparasiticAntiprotozoalAntiviralBVDVCMVDengue VirusApoptosis >>Apoptosis InducerBcl-2c-Mycc-RETC/EBPCARDCaspase
DAPKIAPAutophagy >>AutophagyLC3LRRK2LysosomemitoNEETPPTSPHKTFEBULKBiochemical Reagent >>Cationic & Neutral LipidsDendrimersDye ReagentIntermediate and OthersCell Cycle >>APCAurora KinaseBUBCasein Kinase
Cdc25CDKChkCRM1DHFRCytoskeleton >>ActinArp2/3 ComplexCytoplasmic dyneinDynaminFAKFilamin-AGap JunctionIntegrinMicrotubule/TubulinDNA Damage >>AP endonucleaseATAD5ATM/ATRBRCADNA Alkylator/CrosslinkerMore >>
Material Science
Aggregation-Induced Emission >>Other AIE BlocksTetraphenylethylene SeriesElectronic Materials >>Battery MaterialsDye-Sensitized Solar Cell (DSSC) MaterialsElectronic MaterialLiquid Crystal (LC) MaterialsMolecular ConductorsOrganic Light-Emitting Diode (OLED) MaterialsOrganic Solar Cell (OPV) MaterialsOrganic Transistor (OFET) MaterialsPerovskite Solar Cell (PSC) MaterialsMagnetic Materials >>Magnetic Ionic LiquidsMagnetic MaterialMagnetic Metal Complexes Organic Radicals Material Chemical Compounds >>Ligands for Functional Metal ComplexesLiquid Crystal (LC) Building BlocksPhthalocyanine Building BlocksPolymer and Macromolecule Semiconductor Building BlocksSmall Molecule Semiconductor Building BlocksSolubility Enhancing Reagents Supramolecular Host Materials MOF Ligands >>
Carboxylic MOF ligandsMOF ligands of nitrogenous carboxylic acidsNitrogen containing MOF ligandsOther MOF ligandsNanomaterials >>Carbon NanomaterialsCeramic MembranesDendrimersGold NanoparticlesIron Oxide NanoparticlesMaterials by ApplicationMesoporous MaterialsMetals and Metal AlloysNano Minerals: NanoclaysOLED Materials >>DopantHostHTMOLED IntermediatesOther OLED related materialsOLED Materials >>DopantHostHTMOther OLED related metarialsOptical Materials >>Coumarin Dyes
Cyanine and Squarylium DyesDCM DyesDipyrromethene DyesFluorescence MaterialsFluorescent ProbesHeat and Pressure Sensitive DyesNear-Infrared (NIR) DyesOrganic Non-Linear Optical (NLO) MaterialsOrganic monomer of COF >>Aldehyde based COF monomerAlkynyl COF monomerAmino COF monomerBoric acid COF monomerCyano COF monomerMultifunctional COF monomerOther COF monomerTriphene seriesOrganic Pigments >>Organic PigmentOther Materials >>Mateial OtherPolymer Science >>MonomersPolymer AdditivesPolymerization ReagentsPolymersResins
Life Science
ADC-linkers >>ADC-linkerAmino Acids >>Amino AcidAmino Acid DerivativesAnalytical Science >>Stable IsotopesAPIs >>API
DNA/RNA >>Nucleosides and NucleotidesEnzymes >>EnzymeOther Life Science >>CRISPR/Cas9eIFIRE1Neuronal Signaling
Sigma ReceptorPeptides >>PeptideStandard Substrates >>Standard SubstrateSteroids >>Other Steroids
Contact Us
Home Cart 0 Sign in  
X
Chemistry
Heterocyclic Building Blocks
Indoles
6-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde
Chemistry
Inhibitors/Agonists
Heterocyclic Building Blocks
Organic Building Blocks Stapled Peptide
Indoles
Chlorides Aldehydes Other Aromatic Heterocycles PKA/AKAP (stapled peptide)

[ CAS No. 383875-59-0 ]

{[proInfo.proName]} ,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
3d Animation Molecule Structure of 383875-59-0
Chemical Structure| 383875-59-0
Chemical Structure| 383875-59-0
Structure of 383875-59-0 * Storage: {[proInfo.prStorage]}
Cart0 Add to My Favorites Bulk Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

For Research Only 100K+ Compounds Competitive Price 1-2 Day Shipping

Quality Control of [ 383875-59-0 ]

COA NMR CNMR HPLC LC-MS

Related Doc. of [ 383875-59-0 ]

SDS Specification
Alternatived Products of [ 383875-59-0 ]

Product Details of [ 383875-59-0 ]

CAS No. :383875-59-0 MDL No. :MFCD10697640
Formula : C8H5ClN2O Boiling Point : -
Linear Structure Formula :- InChI Key :XZFBLEDAMKMVEG-UHFFFAOYSA-N
M.W :180.59 Pubchem ID :18400607
Synonyms :

Calculated chemistry of [ 383875-59-0 ]

Physicochemical Properties

Num. heavy atoms : 12
Num. arom. heavy atoms : 9
Fraction Csp3 : 0.0
Num. rotatable bonds : 1
Num. H-bond acceptors : 2.0
Num. H-bond donors : 1.0
Molar Refractivity : 46.49
TPSA : 45.75 Ų

Pharmacokinetics

GI absorption : High
BBB permeant : Yes
P-gp substrate : No
CYP1A2 inhibitor : Yes
CYP2C19 inhibitor : No
CYP2C9 inhibitor : No
CYP2D6 inhibitor : No
CYP3A4 inhibitor : No
Log Kp (skin permeation) : -6.17 cm/s

Lipophilicity

Log Po/w (iLOGP) : 1.28
Log Po/w (XLOGP3) : 1.74
Log Po/w (WLOGP) : 2.03
Log Po/w (MLOGP) : 0.94
Log Po/w (SILICOS-IT) : 2.78
Consensus Log Po/w : 1.75

Druglikeness

Lipinski : 0.0
Ghose : None
Veber : 0.0
Egan : 0.0
Muegge : 1.0
Bioavailability Score : 0.55

Water Solubility

Log S (ESOL) : -2.54
Solubility : 0.515 mg/ml ; 0.00285 mol/l
Class : Soluble
Log S (Ali) : -2.32
Solubility : 0.869 mg/ml ; 0.00481 mol/l
Class : Soluble
Log S (SILICOS-IT) : -3.47
Solubility : 0.0606 mg/ml ; 0.000336 mol/l
Class : Soluble

Medicinal Chemistry

PAINS : 0.0 alert
Brenk : 2.0 alert
Leadlikeness : 1.0
Synthetic accessibility : 1.46

Safety of [ 383875-59-0 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P305+P351+P338 UN#:N/A
Hazard Statements:H302-H315-H319-H335 Packing Group:N/A
GHS Pictogram:

Tags: 383875-59-0 synthesis path| 383875-59-0 SDS| 383875-59-0 COA| 383875-59-0 purity| 383875-59-0 application| 383875-59-0 NMR| 383875-59-0 COA| 383875-59-0 structure

Same Skeleton Products
Related Products
Historical Records

Related Functional Groups of
[ 383875-59-0 ]

Chlorides

Chemical Structure| 4894-32-0

[ 4894-32-0 ]

6-Chloro-4-methyl-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde

Similarity: 0.98

Chemical Structure| 1260383-22-9

[ 1260383-22-9 ]

1-(6-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)ethanone

Similarity: 0.90

Chemical Structure| 915140-96-4

[ 915140-96-4 ]

6-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid

Similarity: 0.89

Chemical Structure| 1211531-25-7

[ 1211531-25-7 ]

6-Chloro-3-methyl-1H-pyrrolo[2,3-b]pyridine

Similarity: 0.87

Chemical Structure| 908287-21-8

[ 908287-21-8 ]

4-Chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbaldehyde

Similarity: 0.86

Aldehydes

Chemical Structure| 4894-32-0

[ 4894-32-0 ]

6-Chloro-4-methyl-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde

Similarity: 0.98

Chemical Structure| 908287-21-8

[ 908287-21-8 ]

4-Chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbaldehyde

Similarity: 0.86

Chemical Structure| 1638767-57-3

[ 1638767-57-3 ]

2,4-Dichloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbaldehyde

Similarity: 0.84

Chemical Structure| 954112-61-9

[ 954112-61-9 ]

5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde

Similarity: 0.83

Chemical Structure| 918515-16-9

[ 918515-16-9 ]

4-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde

Similarity: 0.81

Related Parent Nucleus of
[ 383875-59-0 ]

Other Aromatic Heterocycles

Chemical Structure| 4894-32-0

[ 4894-32-0 ]

6-Chloro-4-methyl-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde

Similarity: 0.98

Chemical Structure| 1260383-22-9

[ 1260383-22-9 ]

1-(6-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)ethanone

Similarity: 0.90

Chemical Structure| 915140-96-4

[ 915140-96-4 ]

6-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid

Similarity: 0.89

Chemical Structure| 1211531-25-7

[ 1211531-25-7 ]

6-Chloro-3-methyl-1H-pyrrolo[2,3-b]pyridine

Similarity: 0.87

Chemical Structure| 908287-21-8

[ 908287-21-8 ]

4-Chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbaldehyde

Similarity: 0.86