Home Cart Sign in  
Chemical Structure| 3854-80-6 Chemical Structure| 3854-80-6

Structure of 3854-80-6

Chemical Structure| 3854-80-6

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 3854-80-6 ]

CAS No. :3854-80-6
Formula : C15H8F2O
M.W : 242.22
SMILES Code : O=C1C(C2=CC=C(F)C=C2)=C1C3=CC=C(F)C=C3
MDL No. :N/A

Safety of [ 3854-80-6 ]

Application In Synthesis of [ 3854-80-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 3854-80-6 ]

[ 3854-80-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 3382-18-1 ]
  • [ 3854-80-6 ]
  • 8,9-dimethoxy-10b-hydroxy-2,3-bis(4-fluorophenyl)-5,6-dihydropyrrolo[2,1-a]isoquinolin-1-one [ No CAS ]
YieldReaction ConditionsOperation in experiment
34% With air; In chloroform; at 20℃; for 3h; To a stirred solution of 6,7-dimethoxy-3,4-dihydroisoquinoline[34] (0.096 g, 0.499 mmol) in chloroform (5 mL), was added 2,3-bis(4-fluorophenyl)cycloprop-2-en-1-one [36] (0.121 g,0.497 mmol) at room temperature under an air atmosphere. The reaction mixture was stirred at room temperature for 3 h and then solvents were removed by rotary evaporation. The crude product was purified by silica chromatography to afford the title compoundas a pale green oil (0.075 g, 34% yield). Rf 0.3 (CH2Cl2/MeOH, 5:1);1H NMR (600 MHz, CDCl3) δ: 7.63 (1H, s, Ar), 7.41 (2H, bs, Ar), 7.19(2H, bs, Ar), 6.95e6.97 (2H, m, Ar), 6.84e6.87 (2H, m, Ar), 6.56 (1H,s, Ar), 4.00 (3H, s, OCH3), 3.85e3.98 (2H, s, OH CHH), 3.88 (3H, s,OCH3), 3.60e3.66 (1H, m, CHH), 2.57e2.61 (1H, m, CHH), 2.50e2.53(1H, m, CHH); 13C NMR (150 MHz, CDCl3) δ: 198.0 (C]O),172.4 (qC),163.0 (d, J 251.1 Hz, qCF), 161.2 (d, J 244.3 Hz, qCF), 149.5(qC), 148.6 (qC), 130.4 (2C, d, J 7.8 Hz, 2 CHm-F), 126.49 (qC),126.45 (bs, qCp-F), 126.2 (d, J 3.4 Hz, qCp-F), 124.8 (qC), 116.7 (d,J 21.8 Hz, CHo-F),115.0 (d, J 21.2 Hz, CHo-F),112.6 (qC),110.3 (2C,2 CH), 85.5 (qCOH), 56.2 (OCH3), 55.9 (OCH3), 40.8 (CH2), 21.8(CH2); IR (neat, cm-1) ν max: 3460.4, 2928.0, 2853.3, 2117.0, 1677.6,1513.9, 1265.8, 1226.0, 1154.9, 1132.2; HRMS: [M H] forC26H22F2NO4 calculated 450.1518, found 450.1509.
 

Historical Records