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Chemical Structure| 38955-11-2 Chemical Structure| 38955-11-2

Structure of 38955-11-2

Chemical Structure| 38955-11-2

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Product Details of [ 38955-11-2 ]

CAS No. :38955-11-2
Formula : C5H6N2O2
M.W : 126.11
SMILES Code : O=C(C1=CC(C)=NO1)N
MDL No. :MFCD16104695

Safety of [ 38955-11-2 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Application In Synthesis of [ 38955-11-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 38955-11-2 ]

[ 38955-11-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 4857-42-5 ]
  • conc. ammonium hydroxide [ No CAS ]
  • [ 38955-11-2 ]
YieldReaction ConditionsOperation in experiment
In thionyl chloride; PREPARATION 15 3-Methyl-5-isoxazolecarboxamide <strong>[4857-42-5]3-Methyl-5-isoxazolecarboxylic acid</strong> (20 g.) was refluxed for 10 hours in 350 ml. of thionyl chloride, then stirred at room temperature for 16 hours, clarified by filtration and evaporated to an oil. The oil was multiply triturated with hot hexane, and the combined hexane triturates evaporated to yield acid chloride (16.2 to 21 g.) as a solid. With stirring, acid chloride prepared in the manner (35 g.) was added portionwise to 300 ml. of conc. ammonium hydroxide at room temperature. After granulating for 1 hour, title product was recovered by filtration (24.2 g., m.p 180°-182° C.).
 

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