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Chemical Structure| 391954-24-8 Chemical Structure| 391954-24-8

Structure of 391954-24-8

Chemical Structure| 391954-24-8

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Product Details of [ 391954-24-8 ]

CAS No. :391954-24-8
Formula : C13H19BrClNO
M.W : 320.65
SMILES Code : COC1=CC=C(C(CC2CCNCC2)=C1)Br.[H]Cl
MDL No. :MFCD31555592

Safety of [ 391954-24-8 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Application In Synthesis of [ 391954-24-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 391954-24-8 ]

[ 391954-24-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 391954-24-8 ]
  • [ 16799-05-6 ]
  • 4-(2-bromo-5-methoxybenzyl)-1-[2-(3-chlorophenyl)ethyl]piperidine [ No CAS ]
YieldReaction ConditionsOperation in experiment
86% With potassium carbonate; In acetonitrile; for 24h;Inert atmosphere; Reflux; General procedure: To a mixture of the benzyl piperidine intermediate 5 (200 mg,0.770 mmol) and potassium carbonate (266 mg, 1.93 mmol) inMeCN (3.0 mL) was added (2-bromoethyl)benzene (137 muL, 1.00 mmol). After reflux for 24 h, EtOAc (9.0 mL) was added to thereaction mixture and the whole was filtered. The filtrate was evaporatedin vacuo and the residue was purified by silica gel chromatographyusing 0-1% MeOH/CHCl3 as eluent to give 228 mg(90%) of the title compound as a pale yellow solid.
 

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