Home Cart Sign in  
Chemical Structure| 392-70-1 Chemical Structure| 392-70-1

Structure of 392-70-1

Chemical Structure| 392-70-1

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 392-70-1 ]

CAS No. :392-70-1
Formula : C8H10FN
M.W : 139.17
SMILES Code : NC1=C(C)C=C(F)C=C1C
MDL No. :MFCD03792669
InChI Key :MPNDLCBMLBACDD-UHFFFAOYSA-N
Pubchem ID :1403908

Safety of [ 392-70-1 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 392-70-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 392-70-1 ]

[ 392-70-1 ] Synthesis Path-Downstream   1~3

  • 3
  • [ 392-70-1 ]
  • [ 25271-35-6 ]
  • N-(4-fluoro-2,6-dimethylphenyl)-1-methylpiperidine-2-carboxamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
16% DCM under nitrogen TEA (5.12 g, 50.6 mmol, 4.4 eq) was added to <strong>[25271-35-6]1-methylpiperidine-2-carboxylic acid hydrochloride</strong> (2.27 g, 12.65 mmol, 1.1 eq) contained in methanol (46 mL, c = 0.25) The mixture was stirred at room temperature for 30 minutes. The mixture was cooled to 0 C in an ice bath, and then ClCO2Et was slowly added dropwise over 20 minutes. To this mixture was added dropwise 3 (1.6 g, 11.5 mmol, 1.0 eq) in DCM (2 mL) and stirred overnight. The residue after rotary evaporation was purified by column chromatography to give the desired product 4 (0.5 g, 16% yield).
 

Historical Records

Technical Information

Categories