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Chemical Structure| 39619-07-3 Chemical Structure| 39619-07-3

Structure of 39619-07-3

Chemical Structure| 39619-07-3

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Product Details of [ 39619-07-3 ]

CAS No. :39619-07-3
Formula : C4H4Cl2O2
M.W : 154.98
SMILES Code : O=C(Cl)C(C)C(Cl)=O
MDL No. :N/A

Safety of [ 39619-07-3 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H314-H226
Precautionary Statements:P501-P240-P210-P233-P243-P241-P242-P264-P280-P370+P378-P303+P361+P353-P301+P330+P331-P363-P304+P340+P310-P305+P351+P338+P310-P403+P235-P405
Class:8(3)
UN#:2920
Packing Group:

Application In Synthesis of [ 39619-07-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 39619-07-3 ]

[ 39619-07-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 7149-18-0 ]
  • [ 39619-07-3 ]
  • methyl 3-oxo-3-[(2-ethoxycarbonylcyclopenten-1-yl)amino]propanoate [ No CAS ]
YieldReaction ConditionsOperation in experiment
With triethylamine; In dichloromethane; Part C Ethyl 2-amino-1-cyclopentene-1-carboxylate (43.8 g, 0.28 moles) was combined with triethyl amine (42.9 mL, 0.31 moles) and methylene chloride (850 mL) and cooled to 0 C. Methyl malonyl chloride (33.4 mL, 0.31 mole) was added dropwise to the reaction mixture. After the addition the reaction was stirred for about 1 hr at 0 C. The reaction mixture was quenched with water (500 mL). The layers were separated. The aqueous layer was extracted with methylene chloride (4*100 mL). The organic layers were combined, dried over magnesium sulfate and evaporated under vacuum to provide 56.2 g of an oil. The oil was purified by silica gel chromatography eluding with hexane:ethyl acetate (70:30) to provide 46 g of methyl 3-oxo-3-[(2-ethoxycarbonylcyclopenten-1-yl)amino]propanoate as a clear oil.
 

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