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Chemical Structure| 100-19-6 Chemical Structure| 100-19-6
Chemical Structure| 100-19-6

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Synonyms: 4'-Nitroacetophenone

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Product Citations

Product Citations

Jang, Mingyeong ; Lim, Taeho ; Park, Byoung Yong ; Han, Min Su ;

Abstract: In this study, we developed a metal-free and highly chemoselective method for the reduction of aromatic nitro compounds. This reduction was performed using tetrahydroxydiboron [B2(OH)4] as the reductant and 4,4'-bipyridine as the organocatalyst and could be completed within 5 min at room temperature. Under optimal conditions, nitroarenes with sensitive functional groups, such as vinyl, ethynyl, carbonyl, and halogen, were converted into the corresponding anilines with excellent selectivity while avoiding the undesirable reduction of the sensitive functional groups.

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Product Details of 4′-Nitroacetophenone

CAS No. :100-19-6
Formula : C8H7NO3
M.W : 165.15
SMILES Code : CC(C1=CC=C([N+]([O-])=O)C=C1)=O
Synonyms :
4'-Nitroacetophenone
MDL No. :MFCD00007355
InChI Key :YQYGPGKTNQNXMH-UHFFFAOYSA-N
Pubchem ID :7487

Safety of 4′-Nitroacetophenone

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P280-P305+P351+P338

Application In Synthesis of 4′-Nitroacetophenone

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 100-19-6 ]
  • Downstream synthetic route of [ 100-19-6 ]

[ 100-19-6 ] Synthesis Path-Upstream   1~2

  • 1
  • [ 108-94-1 ]
  • [ 100-19-6 ]
  • [ 23600-83-1 ]
References: [1] Organic Letters, 2012, vol. 14, # 7, p. 1692 - 1695.
  • 2
  • [ 100-19-6 ]
  • [ 98-80-6 ]
  • [ 23600-83-1 ]
References: [1] Angewandte Chemie - International Edition, 2019, [2] Angew. Chem., 2019, vol. 131, # 7, p. 2151 - 2155,5.
 

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