[ CAS No. 17763-80-3 ] {[proInfo.proName]}

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Quality Control of [ 17763-80-3 ]

COA NMR CNMR HPLC LC-MS

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Product Details of [ 17763-80-3 ]

CAS No. :	17763-80-3	MDL No. :	MFCD00192354
Formula :	C₇H₄F₃NO₅S	Boiling Point :	-
Linear Structure Formula :	-	InChI Key :	NDTIXHNCNLKURN-UHFFFAOYSA-N
M.W :	271.17	Pubchem ID :	549870
Synonyms :

Safety of [ 17763-80-3 ]

Signal Word:	Danger	Class:	8
Precautionary Statements:	P280-P305+P351+P338-P310	UN#:	3261
Hazard Statements:	H314	Packing Group:	Ⅲ
GHS Pictogram:

Application In Synthesis of [ 17763-80-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Upstream synthesis route of [ 17763-80-3 ]
Downstream synthetic route of [ 17763-80-3 ]

[ 17763-80-3 ] Synthesis Path-Upstream 1~9

1
[ 17763-80-3 ]
[ 59147-02-3 ]

Reference： [1] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 3, p. 1397 - 1401

2
[ 110-89-4 ]
[ 17763-80-3 ]
[ 6574-15-8 ]

Reference： [1] Synthesis, 1990, # 12, p. 1145 - 1147
[2] Synlett, 1999, # 10, p. 1559 - 1562
[3] Organic Letters, 2004, vol. 6, # 6, p. 985 - 987
[4] Journal of Organic Chemistry, 2000, vol. 65, # 4, p. 1158 - 1174

3
[ 110-91-8 ]
[ 17763-80-3 ]
[ 10389-51-2 ]

Reference： [1] Synthesis, 1990, # 12, p. 1145 - 1147

4
[ 2759-28-6 ]
[ 17763-80-3 ]
[ 16155-08-1 ]

Reference： [1] Synthesis, 1990, # 12, p. 1145 - 1147

5
[ 17763-80-3 ]
[ 42790-42-1 ]
[ 16155-08-1 ]

Reference： [1] Helvetica Chimica Acta, 2017, vol. 100, # 8,

6
[ 17763-80-3 ]
[ 121219-12-3 ]

Reference： [1] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 3, p. 1397 - 1401

7
[ 17763-80-3 ]
[ 134150-01-9 ]

Reference： [1] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 3, p. 1397 - 1401

8
[ 17763-80-3 ]
[ 17763-67-6 ]
[ 171364-83-3 ]

Reference： [1] Tetrahedron Letters, 1997, vol. 38, # 19, p. 3447 - 3450

9
[ 17763-80-3 ]
[ 1092390-02-7 ]

Reference： [1] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 3, p. 1397 - 1401

[ 17763-80-3 ] Synthesis Path-Downstream 1~47

1
[ 110-89-4 ]
[ 17763-80-3 ]
[ 6574-15-8 ]

Reference： [1]Synthesis,1990,p. 1145 - 1147
[2]Synlett,1999,p. 1559 - 1562
[3]Organic Letters,2004,vol. 6,p. 985 - 987
[4]Journal of Organic Chemistry,2000,vol. 65,p. 1158 - 1174

2
[ 30089-00-0 ]
[ 17763-80-3 ]
[ 16245-79-7 ]
[ 78723-40-7 ]

Yield	Reaction Conditions	Operation in experiment
1: 48% 2: 30%	With potassium phosphate In 1,4-dioxane at 85℃; for 5h;

Reference： [1]Oh-e, Takayuki; Miyaura, Norio; Suzuki, Akira [Journal of Organic Chemistry, 1993, vol. 58, # 8, p. 2201 - 2208]

3
[ 17763-80-3 ]
[ 62-53-3 ]
[ 836-30-6 ]

Yield	Reaction Conditions	Operation in experiment
35%	In acetonitrile at 100℃; for 20h;

Reference： [1]Kotsuki; Kobayashi; Suenaga; Nishizawa [Synthesis, 1990, # 12, p. 1145 - 1147]

4
[ 17763-80-3 ]
[ 100-46-9 ]
[ 14309-92-3 ]

Yield	Reaction Conditions	Operation in experiment
61%	In acetonitrile for 24h; Heating;

Reference： [1]Kotsuki; Kobayashi; Suenaga; Nishizawa [Synthesis, 1990, # 12, p. 1145 - 1147]

5
[ 17763-80-3 ]
[ 824-39-5 ]
[ 5950-83-4 ]

Reference： [1]Journal of the Chemical Society. Perkin transactions I,1978,p. 295 - 298

6
[ 17763-80-3 ]
tris (3,3,4,4,5,5,6,6,7,7,8,8,8-Tridecafluorooctyl)(2'-pyridyl)tin [ No CAS ]
[ 4282-47-7 ]

Reference： [1]Journal of Organic Chemistry,1996,vol. 61,p. 6480 - 6481

7
[ 17763-80-3 ]
tris[2-(perfluorohexyl)ethyl](4'-methoxyphenyl)tin [ No CAS ]
[ 100-02-7 ]
[ 2143-90-0 ]
[ 2132-80-1 ]

Yield	Reaction Conditions	Operation in experiment
1: 8% 2: 10% 3: 86%	With bis-triphenylphosphine-palladium(II) chloride; lithium chloride In tetrahydrofuran; N,N-dimethyl-formamide at 80℃; for 22h;

Reference： [1]Curran, Dennis P.; Hoshino, Masahide [Journal of Organic Chemistry, 1996, vol. 61, # 19, p. 6480 - 6481]

8
[ 17763-80-3 ]
[ 17763-67-6 ]
[ 171364-83-3 ]

Reference： [1]Tetrahedron Letters,1997,vol. 38,p. 3447 - 3450

9
[ 621-59-0 ]
[ 17763-80-3 ]
[ 59099-58-0 ]

Reference： [1]Tetrahedron Letters,1997,vol. 38,p. 1181 - 1182

10
[ 540-38-5 ]
[ 17763-80-3 ]
[ 109586-39-2 ]

Yield	Reaction Conditions	Operation in experiment
90%	With potassium carbonate In N,N-dimethyl-formamide for 1.5h; Ambient temperature;
90%	With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 1.5h;
88%	With 7-methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene on polystyrene.HL In acetonitrile at 80℃;

Reference： [1]Zhu, Jieping; Bigot, Antony; Elise, Marie; Dau, Tran Huu [Tetrahedron Letters, 1997, vol. 38, # 7, p. 1181 - 1182]
[2]Neuville, Luc; Bigot, Antony; Tran Huu Dau, Marie Elise; Zhu, Jieping [Journal of Organic Chemistry, 1999, vol. 64, # 20, p. 7638 - 7642]
[3]Boisnard, Sabine; Chastanet, Jaqueline; Zhu, Jieping [Tetrahedron Letters, 1999, vol. 40, # 42, p. 7469 - 7472]

11
[ 17763-80-3 ]
[ 135-19-3 ]
[ 3857-83-8 ]

Yield	Reaction Conditions	Operation in experiment
100%	With 7-methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene on polystyrene.HL In acetonitrile at 80℃;
92%	With potassium carbonate In N,N-dimethyl-formamide for 1h; Ambient temperature;
92%	With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 1h;

Reference： [1]Boisnard, Sabine; Chastanet, Jaqueline; Zhu, Jieping [Tetrahedron Letters, 1999, vol. 40, # 42, p. 7469 - 7472]
[2]Zhu, Jieping; Bigot, Antony; Elise, Marie; Dau, Tran Huu [Tetrahedron Letters, 1997, vol. 38, # 7, p. 1181 - 1182]
[3]Neuville, Luc; Bigot, Antony; Tran Huu Dau, Marie Elise; Zhu, Jieping [Journal of Organic Chemistry, 1999, vol. 64, # 20, p. 7638 - 7642]

12
[ 17763-80-3 ]
tris[2-(perfluorohexyl)ethyl](4'-methoxyphenyl)tin [ No CAS ]
[ 100-02-7 ]
[ 2143-90-0 ]
[ 2132-80-1 ]
chlorotris[2-(perfluorohexyl)ethyl]tin [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
1: 86% 2: 8% 3: 10%	With lithium chloride In tetrahydrofuran; N,N-dimethyl-formamide at 80℃; for 22h;

Reference： [1]Hoshino, Masahide; Degenkolb, Peter; Curran, Dennis P. [Journal of Organic Chemistry, 1997, vol. 62, # 24, p. 8341 - 8349]

13
[ 17763-80-3 ]
tris(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)(4'-methylphenyl)tin [ No CAS ]
[ 613-33-2 ]
[ 2143-88-6 ]

Reference： [1]Journal of Organic Chemistry,1997,vol. 62,p. 8341 - 8349

14
[ 98-54-4 ]
[ 17763-80-3 ]
[ 154318-75-9 ]

Reference： [1]Tetrahedron Letters,1999,vol. 40,p. 7469 - 7472
[2]Journal of Organic Chemistry,1999,vol. 64,p. 7638 - 7642

15
[ 34420-17-2 ]
[ 17763-80-3 ]
[ 14310-29-3 ]

Reference： [1]Tetrahedron,2002,vol. 58,p. 1465 - 1470

16
[ 18052-27-2 ]
[ 17763-80-3 ]
[ 620-88-2 ]

Yield	Reaction Conditions	Operation in experiment
90%	With caesium carbonate In N,N-dimethyl-formamide at 100℃;

Reference： [1]Cui, Sun-Liang; Jiang, Zhi-Yong; Wang, Yan-Guang [Synlett, 2004, # 10, p. 1829 - 1831]

17
[ 17763-80-3 ]
[ 1528-74-1 ]

Yield	Reaction Conditions	Operation in experiment
75%	With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium carbonate; bis(pinacol)diborane In 1,4-dioxane at 80℃; for 14h;

Reference： [1]Nising, Carl F.; Schmid, Ulrike K.; Nieger, Martin; Braese, Stefan [Journal of Organic Chemistry, 2004, vol. 69, # 20, p. 6830 - 6833]

18
[ 17763-80-3 ]
[ 108-98-5 ]
[ 952-97-6 ]

Yield	Reaction Conditions	Operation in experiment
92%	With N-ethyl-N,N-diisopropylamine; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene In 1,4-dioxane for 7h; Heating;
92%	With N-ethyl-N,N-diisopropylamine In 1,4-dioxane for 7h; Heating / reflux;
	With i-Pr₂NEt	19 Production of 4-nitrophenyl phenyl sulfide: Example 19 Production of 4-nitrophenyl phenyl sulfide: Heating and refluxing time: 7 hours. Aryl sulfonate and its amount used: 4-Nitrobenzene trifluoromethanesulfonate (542 mg, 2 mmol). Thiol compound and its amount used: Thiophenol (205 μL, 2 mmol). Amount of Pd2(dba)3 used: 46 mg, 0.05 mmol. Amount of Xantphos used: 58 mg, 0.1 mmol. Base and its amount used: i-Pr2NEt (700 μL, 4 mmol). Amount of 1,4-dioxane used: 10.8 mL. Property, yield and yield percentage of 4-nitrophenyl phenyl sulfide: Pale yellow solid; yield 425 mg; yield percentage 92 %. Development solvent in flash column chromatography: Hexane/ethyl acetate = 10/1. Melting point: 54°C-55°C. 1H NMR (CDCl3, 500 MHz) δ ppm: 8.06 (dt, 2H, J = 2.0 Hz, 7.0 Hz), 7.53-7.55 (m, 2H), 7.46 (d, 2H, J = 2.4 Hz), 7.45 (d, 1H, J = 1.0 Hz), 7.18 (dt, 2H, J = 2.0 Hz, 7.0 Hz). 13C NMR (CDCl3, 125 MHz) δ ppm: 148.90, 145.78, 135.15, 130.88, 130.44, 130.07, 127.11, 124.44.

Reference： [1]Itoh, Takahiro; Mase, Toshiaki [Organic Letters, 2004, vol. 6, # 24, p. 4587 - 4590]
[2]Current Patent Assignee: MERCK & CO INC - WO2006/38741, 2006, A1 Location in patent: Page/Page column 45; 61-62
[3]Current Patent Assignee: MERCK & CO INC - EP1806337, 2007, A1

19
[ 17763-80-3 ]
[ 156275-96-6 ]
[ 1849-36-1 ]
triisopropyl-(4-nitrophenylsulfanyl)-silane [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
1: 56% 2: 34%	With caesium carbonate; triphenylphosphine In toluene at 100℃;

Reference： [1]Kreis, Michael; Braese, Stefan [Advanced Synthesis and Catalysis, 2005, vol. 347, # 2-3, p. 313 - 319]

20
[ 17763-80-3 ]
potassium (4-chlorophenyl)trifluoroborate [ No CAS ]
[ 6242-97-3 ]

Yield	Reaction Conditions	Operation in experiment
86%	With palladium diacetate In ethanol at 95℃; for 0.25h; microwave irradiation;

Reference： [1]Kabalka, George W.; Zhou, Li-Li; Naravane, Abhijit [Tetrahedron Letters, 2006, vol. 47, # 38, p. 6887 - 6889]

21
[ 910251-11-5 ]
[ 17763-80-3 ]
[ 1515-83-9 ]

Yield	Reaction Conditions	Operation in experiment
68%	With caesium carbonate;palladium diacetate; tris-(o-tolyl)phosphine; In 1,4-dioxane; water; at 95℃; for 4h;	To a mixture of 4-nitrophenyl trifluoromethanesulfonate (30 mg, 0.11 mmol) and 1,4-dioxane (3 ml) were added water (0.3 ml), cesium carbonate (0.11 g, 0.34 mmol), <strong>[910251-11-5]potassium methoxymethyltrifluoroborate</strong> (17 mg, 0.11 mmol), palladium (II) acetate (1.3 mg, 0.0056 mmol) and tri-o-tolylphosphine (8.5 mg, 0.028 mmol). Then, the reaction mixture was stirred at 95C (external temperature) for 4 hours. After the reaction mixture was cooled at room temperature, water and heptane were added to the mixture, and the organic layer was separated. The organic layer was filtered, and the solvent was distilled off under reduced pressure. The residue was purified by NH-silica gel column chromatography (heptane:ethyl acetate=10:1) to obtain the title compound (13 mg, 0.078 mmol, 68%). 1H-NMR Spectrum (CDCl3) delta (ppm) : 3.45 (3H, s), 4. 56 (2H, s), 7.50 (2H, d, J=9.0Hz), 8.21(2H, d, J=8.8Hz).

Reference： [1]Patent: EP1867650,2007,A1 .Location in patent: Page/Page column 35

22
[ 17763-80-3 ]
[ 33397-21-6 ]
[ 2143-90-0 ]

Yield	Reaction Conditions	Operation in experiment
73%	With potassium phosphate; triphenylphosphine In N,N-dimethyl-formamide at 90℃; for 1h;

Reference： [1]Rao, Maddali L.N.; Banerjee, Debasis; Jadhav, Deepak N. [Tetrahedron Letters, 2007, vol. 48, # 38, p. 6644 - 6647]

23
[ 17763-80-3 ]
[ 33282-25-6 ]

Reference： [1]Journal of the American Chemical Society,2007,vol. 129,p. 9613 - 9615

24
[ 17763-80-3 ]
[ 121-33-5 ]
[ 194018-68-3 ]

Yield	Reaction Conditions	Operation in experiment
94%	With potassium carbonate In DMF (N,N-dimethyl-formamide) at 20℃; for 3h;	XV. C C. 4-[(1-Ethylpropylamino)-methyl]-2-hydroxybenzonitrile SCHEME 43 Vanillin 4-Formyl-2-methoxyphenyl trifluoromethanesulfonate [0275] To a solution of vanillin (500 mg, 3.286 mmol) in DMF (10 mL) at room temp, was added potassium carbonate (908 mg, 6,572 mmol) and 4- nitrophenyl trifluoromethanesulfonate (1, 34g, 4,929 mmol) and the reaction mixture was stirred for 3h. Et20 was added to the reaction mixture and the organic layer was washed 3 times with water, dried, filtered and concentrated. The crude compound was then purified by flash chromatography (ethyl acetate-hexanes/1 : 9 to 3: 7) to provide sulfonate (880 mg, 94%). 1H RMN (400 MHz, CDC13) 8 : 4.03 (s, 3H), 7.44 (d, J= 8. 2 Hz, 1H), 7.54 (dd, lH, J= 1. 7 and 8.2 Hz), 7.59 (d, 1H, J= 1. 7 Hz), 10.02 (s, 1H).
	With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 8h;	A To a solution of vanillin (20.0 g, 131 mmol) in DMF (200 mL) at room temperature was added potassium carbonate (36 g, 263 mmol) and 4-nitrophenyl trifluoromethanesulfonate (54.0 g, 197 mmol) and the reaction mixture was stirred for 8 h. EtOAc (600 mL) was added to the reaction mixture and the organic layer was washed three times with water, dried, filtered, and concentrated. The crude compound was then purified by flash chromatography (ethylacetate/hexanes 1 :9 → 3:7) to provide 4-formyl~2-methoxyphenyl trifluoromethanesulfonate..H NMR (CDCI3, 500 MHz) δ 10.02 (s, IH), 7.60 (s, IH), 7.55 (d, J= 8.1 Hz, IH), 7.45 (d, J = 8.0 Hz, IH)5 4.04 (s, 3H); LC/MS (IE, m/z) 284.98 [M + I]+; tR = 3.31 min
	With potassium carbonate In N,N-dimethyl-formamide for 8h;	28.A Step A: 4-Formyl-2-methoxyphenyl trifluoromethanesulfonate Step A: 4-Formyl-2-methoxyphenyl trifluoromethanesulfonate: To a solution of vanillin (20 g,131 mmol) in DMF (200 mL) at room temperature was added potassium carbonate (36.30 g, 263 mmol) and 4-nitrophenyl trifluoromethanesulfonate (53.5 g, 197 mmol) and the reaction mixturewas stirred for 8 hr. EtOAc (600 mL) was added to the reaction mixture and the organic layerwas washed three times with water, dried, filtered, and concentrated. The crude compound wasthen purified by flash chromatography ( ethylacetatelhexanes 1 :9 ~ 3 :7) to provide sulfonate.

	With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 8h;	Step A: 4-Formyl-2-methoxyphenyl trifluoromethanesulfonate Step A: 4-Formyl-2-methoxyphenyl trifluoromethanesulfonate: To a solution of vanillin (20 g, 131 mmol) in DMF (200 mL) at room temperature was added potassium carbonate (36.30 g, 263mmol) and 4-nitrophenyl trifluoromethanesulfonate (53.5 g, 197 mmol) and the reaction mixture was stilTed for 8 hr. EtOAc (600 mL) was added to the reaction mixture and the organic layer was washed three times with water, dried, filtered, and concentrated. The crude compound was then purified by flash chromatography (ethylacetate/hexanes 1:9 -> 3:7) to provide the title compound.
	With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 8h;	12.A Step A: 4-Formyl-2-methoxyphenyl trifluoromethanesulfonate: To a solution of yanillin (20.0 g, 131 mmol) in DMF (200 mL) at room temperature was added potassium carbonate (36 g, 263 mmol) and 4-nitrophenyl trifluoromethanesulfonate (54.0 g, 197 mmol) and the reaction mixturewas stirred for 8 h. EtOAc (600 mL) was added to the reaction mixture and the organie layer was washed three times with water, dried, filtered, and concentrated. The crude compound was then purified by flash chromatography (ethylacetatelhexanes 1:9 -* 3:7) to proyide 4-formyl-2- methoxyphenyl trifluoromethanesulfonate._Lc/MS (IE, miz) 284.98 [M + 1]+;
	With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 8h;	A Step A: 4-formyl-2-methoxyphenyl trifluoromethanesulfonate: General procedure: To a solution of vanillin (20 g, 131 mmol) in DMF(200 mL) at room temperature was added potassium carbonate (36.30 g, 263 mmol) and 4-nitrophenyl trifluoromethanesulfonate(53.5 g, 197 mmol) and the reaction mixture was stirred for 8 hr. EtOAc (600 mL) was added to thereaction mixture and the organic layer was washed three times with water, dried, filtered, and concentrated. Thecrude compound was then purified by flash chromatography (ethylacetate/hexanes 1:9 → 3:7) to provide sulfona
	With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 8h;	Step A: 4-formyl-2-methoxyphenyl trifluoromethanesulfonate: Potassium carbonate (36 g, 263 mmol) and 4-nitrophenyl trifluoromethanesulfonate (54.0 g, 197 mmol) was added to a solution of vanillin (20.0 g, 131 mmol) in DMF (200 mL) at rt and the reaction mixture was stirred for 8 h. EtOAc (600 mL) was added to the reaction mixture and the organic layer washed three times with water, dried, filtered, and concentrated. The crude compound was then purified by flash chromatography (10 -30% ethylacetate/hexanes) to provide 4-formyl-2-methoxyphenyl trifluoromethanesulfonate. LC/MS: [(M+l)]+ = 285

Reference： [1]Current Patent Assignee: ENDORECHERCHE, INC. - WO2005/66194, 2005, A1 Location in patent: Page/Page column 161
[2]Current Patent Assignee: MERCK & CO INC - WO2010/129379, 2010, A1 Location in patent: Page/Page column 57
[3]Current Patent Assignee: MERCK & CO INC - WO2013/28474, 2013, A1 Location in patent: Page/Page column 80
[4]Current Patent Assignee: MERCK & CO INC - WO2014/99633, 2014, A2 Location in patent: Page/Page column 70
[5]Current Patent Assignee: MERCK & CO INC - WO2014/126944, 2014, A2 Location in patent: Page/Page column 45
[6]Current Patent Assignee: MERCK & CO INC - EP2744499, 2016, B1 Location in patent: Paragraph 0184
[7]Current Patent Assignee: MERCK & CO INC - WO2016/60941, 2016, A1 Location in patent: Page/Page column 42

25
[ 60-29-7 ]
[ 17763-80-3 ]
[ 22717-57-3 ]
[ 160013-24-1 ]

Yield	Reaction Conditions	Operation in experiment
	With potassium carbonate In water; N,N-dimethyl-formamide	12.b (b) (b) Methyl 5-methyl-2-trifluoromethanesulphonyloxybenzoate: 13.48 g (81.13 mmol) of methyl 2-hydroxy-5-methylbenzoate obtained in Example 12(a), 22.42 g (162.3 mmol) of potassium carbonate and 135 ml of DMF are introduced into a 500 ml round-bottomed flask under a stream of nitrogen. The mixture is cooled to 0° C. and 22.0 g of 4-nitrotrifluoromethanesulphonyloxybenzene dissolved in 80 ml of DMF are added dropwise. The reaction medium is stirred for two hours 30 minutes at room temperature and then water and ethyl ether are added. The product is extracted with ethyl ether and the organic phase is washed with water to neutral pH, dried over magnesium sulphate and filtered. After evaporating the solvents, 23.89 g (99%) of the expected compound are collected in the form of a colourless liquid. 1 H NMR (CDCl3) δ 2.43 (s, 3H), 3.96 (s, 3H), 7.18 (d, 1H, J=8.4 Hz), 7.41 (dd, 1H, J=8.4/2.3 Hz), 7.89 (d, 1H, J=2.1 Hz).

Reference： [1]Current Patent Assignee: Galderma (in: EQT Partners); Eqt Partners AB - US6150413, 2000, A

26
[ 17763-80-3 ]
[ 5142-75-6 ]
[ 613-33-2 ]
[ 2143-88-6 ]

Reference： [1]Tetrahedron,2008,vol. 64,p. 5762 - 5772

27
[ 17763-80-3 ]
[ 33397-21-6 ]
[ 2143-90-0 ]
[ 2132-80-1 ]

Yield	Reaction Conditions	Operation in experiment
77%	With tetrabutylammomium bromide; caesium carbonate; triphenylphosphine In N,N-dimethyl acetamide at 90℃; for 1h;

Reference： [1]Rao, Maddali L.N.; Jadhav, Deepak N.; Banerjee, Debasis [Tetrahedron, 2008, vol. 64, # 24, p. 5762 - 5772]

28
indium(III) benzenethiolate [ No CAS ]
[ 17763-80-3 ]
[ 952-97-6 ]

Yield	Reaction Conditions	Operation in experiment
89%	With palladium diacetate; N-ethyl-N,N-diisopropylamine; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene In N,N-dimethyl-formamide at 100℃; for 4h; Inert atmosphere;

Reference： [1]Lee, Jae-Young; Phil, Ho Lee [Journal of Organic Chemistry, 2008, vol. 73, # 18, p. 7413 - 7416]

29
[ 17745-45-8 ]
[ 17763-80-3 ]
[ 10342-59-3 ]