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Chemical Structure| 328-90-5 Chemical Structure| 328-90-5
Chemical Structure| 328-90-5

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4-Trifluoromethylsalicylic acid (Desacetyl triflusal) is a salicylic acid derivative with a trifluoromethyl substituent, exhibiting anti-inflammatory and antipyretic properties by inhibiting cyclooxygenase (COX) enzymes and blocking prostaglandin synthesis, potentially useful in treating inflammatory conditions such as arthritis. It also serves as a platelet aggregation inhibitor.

Synonyms: Desacetyl triflusal

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Product Details of 4-Trifluoromethylsalicylic acid

CAS No. :328-90-5
Formula : C8H5F3O3
M.W : 206.12
SMILES Code : OC1=CC(C(F)(F)F)=CC=C1C(O)=O
Synonyms :
Desacetyl triflusal
MDL No. :MFCD01529657
InChI Key :XMLFPUBZFSJWCN-UHFFFAOYSA-N
Pubchem ID :164578

Safety of 4-Trifluoromethylsalicylic acid

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of 4-Trifluoromethylsalicylic acid

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 328-90-5 ]

[ 328-90-5 ] Synthesis Path-Upstream   1~1

  • 1
  • [ 328-90-5 ]
  • [ 917-54-4 ]
  • [ 228572-69-8 ]
References: [1] Organic Letters, 2016, vol. 18, # 15, p. 3766 - 3769.
[2] Patent: US2008/287428, 2008, A1, . Location in patent: Page/Page column 73.
[3] Patent: EP2128157, 2009, A1, . Location in patent: Page/Page column 107.
[4] Patent: WO2010/45401, 2010, A1, . Location in patent: Page/Page column 57-58.
[5] Patent: WO2010/45402, 2010, A1, . Location in patent: Page/Page column 55-56.
[6] Patent: EP1908753, 2008, A1, . Location in patent: Page/Page column 111.
[7] Patent: US2013/158067, 2013, A1, . Location in patent: Paragraph 0323.
 

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