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Chemical Structure| 40227-15-4 Chemical Structure| 40227-15-4

Structure of 40227-15-4

Chemical Structure| 40227-15-4

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Product Details of [ 40227-15-4 ]

CAS No. :40227-15-4
Formula : C6H8N2O4
M.W : 172.14
SMILES Code : O=C(NC(C)=O)C(NC(C)=O)=O
MDL No. :MFCD01838300

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Application In Synthesis of [ 40227-15-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 40227-15-4 ]

[ 40227-15-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 40227-15-4 ]
  • [ 141-43-5 ]
  • [ 1871-89-2 ]
YieldReaction ConditionsOperation in experiment
93% In methanol; EXAMPLE 6 Preparation of N,N'-bis-(2-hydroxyethyl)oxamide A suspension of N,N'-diacetyloxamide (10 g, 0.058 mol) in anhydrous methyl alcohol (50 ml) is charged into a four-necked flask equipped with a reflux condenser, an inlet tube for nitrogen, a dropping funnel, a thermometer, and a magnetic stirrer. A solution of monoethanolamine (8.2 g, 0.134 mol) in anhydrous methyl alcohol (20 ml) is gradually dripped in at 25 C. The reaction is exothermic and the temperature rises up to 60 C. The reaction is allowed to proceed at this temperature for 2 hours, then the reaction mixture is cooled and the precipitate is recovered by filtration. The compound of the title is thus obtained (9.5 g, 0.054 mol, 93% yield) with m.p. 166-69 C. Elemental analysis: Calculated for C6 H12 N2 O4; C 40.91%; H 6.82%; N 15.90%; Calculated for C C 40.91%; H 6.82%; N 15.90%. Found: C 41.0%; H 6.9%; N 15.9%.
 

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