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Chemical Structure| 405-31-2 Chemical Structure| 405-31-2

Structure of Bis(4-fluorophenyl) disulfide
CAS No.: 405-31-2

Chemical Structure| 405-31-2

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Product Details of [ 405-31-2 ]

CAS No. :405-31-2
Formula : C12H8F2S2
M.W : 254.32
SMILES Code : FC1=CC=C(SSC2=CC=C(F)C=C2)C=C1
MDL No. :MFCD00816758

Safety of [ 405-31-2 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362-P403+P233-P501

Application In Synthesis of [ 405-31-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 405-31-2 ]

[ 405-31-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 3240-34-4 ]
  • [ 405-31-2 ]
  • [ 19955-99-8 ]
  • [ 1455451-55-4 ]
YieldReaction ConditionsOperation in experiment
59% With potassium iodide; In dichloromethane; at 20℃; General procedure: DIB (0.6 mmol, 193 mg), ArSSAr (0.3 mmol), and KI (0.5 mmol, 83 mg) were added to a styrene (or their derivatives) solution in CH2Cl2 (0.5 mmol in 2 mL of CH2Cl2), and the suspension mixture was vigorously stirred at room temperature for 2 h. Upon completion, the reaction mixture was quenched by the addition of saturated aqueous sodium thiosulfate (Na2S2O3) (5 mL), and basified with saturated aqueous sodium hydrogen carbonate (NaHCO3) (5 mL). Further stirring was followed by extraction with ethyl acetate (3*15 mL). The combined organic extracts were washed with water (20 mL), brine (20 mL), dried (anhydrous MgSO4), filtered, and concentrated (aspirator). The residue was purified by column chromatography (SiO2) to furnish analytically pure product. 4.2.32 2-((4-Fluorophenyl)thio)-1-(3-formylphenyl)ethyl acetate (3kd) m-Vinylbenzaldehyde (1k) (66 mg, 0.50 mmol). Column chromatography (silica gel; 2% EtOAc/hexanes) yields 3kd (74 mg, 59%); light yellow viscous oil; Rf (10% EtOAc/hexanes) 0.33; IR (neat): νmax 1743, 1700, 1227 cm-1; 1H NMR (300 MHz, CDCl3): δ 10.00 (s, 1H, CHO), 7.86-7.75 (m, 2H, ArH), 7.64-7.44 (m, 2H, ArH), 7.43-7.28 (m, 2H, ArH), 6.99 (br t, J=8.5 Hz, 2H, ArH), 5.91 (dd, J=7.5, 5.8 Hz, 1H, ArCH), 3.38 (dd, J=14.1, 7.5 Hz, 1H, CHH), 3.20 (dd, J=14.1, 5.8 Hz, 1H, CHH), 2.06 (s, 3H, CH3); 13C NMR (75 MHz, CDCl3): δ 191.7, 169.8, 162.0 (d, J=246.2 Hz), 139.9, 136.5, 133.3 (d, J=8.1 Hz), 132.7, 129.9, 129.2, 127.3, 116.1 (d, J=21.8 Hz), 73.8, 41.0, 20.8; HRMS (ESI-TOF): MNa+, found: 341.0615; error=3 ppm requires C17H15FNaO3S 341.0624.
 

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