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CAS No. : | 4167-74-2 | MDL No. : | MFCD01846454 |
Formula : | C10H14O | Boiling Point : | - |
Linear Structure Formula : | - | InChI Key : | GDEHXPCZWFXRKC-UHFFFAOYSA-N |
M.W : | 150.22 | Pubchem ID : | 123212 |
Synonyms : |
|
Num. heavy atoms : | 11 |
Num. arom. heavy atoms : | 6 |
Fraction Csp3 : | 0.4 |
Num. rotatable bonds : | 2 |
Num. H-bond acceptors : | 1.0 |
Num. H-bond donors : | 1.0 |
Molar Refractivity : | 47.85 |
TPSA : | 20.23 Ų |
GI absorption : | High |
BBB permeant : | Yes |
P-gp substrate : | No |
CYP1A2 inhibitor : | Yes |
CYP2C19 inhibitor : | No |
CYP2C9 inhibitor : | No |
CYP2D6 inhibitor : | No |
CYP3A4 inhibitor : | No |
Log Kp (skin permeation) : | -4.82 cm/s |
Log Po/w (iLOGP) : | 2.12 |
Log Po/w (XLOGP3) : | 3.37 |
Log Po/w (WLOGP) : | 2.59 |
Log Po/w (MLOGP) : | 2.76 |
Log Po/w (SILICOS-IT) : | 2.65 |
Consensus Log Po/w : | 2.7 |
Lipinski : | 0.0 |
Ghose : | None |
Veber : | 0.0 |
Egan : | 0.0 |
Muegge : | 2.0 |
Bioavailability Score : | 0.55 |
Log S (ESOL) : | -3.17 |
Solubility : | 0.102 mg/ml ; 0.000682 mol/l |
Class : | Soluble |
Log S (Ali) : | -3.47 |
Solubility : | 0.0505 mg/ml ; 0.000336 mol/l |
Class : | Soluble |
Log S (SILICOS-IT) : | -3.03 |
Solubility : | 0.14 mg/ml ; 0.000931 mol/l |
Class : | Soluble |
PAINS : | 0.0 alert |
Brenk : | 0.0 alert |
Leadlikeness : | 1.0 |
Synthetic accessibility : | 1.0 |
Signal Word: | Warning | Class: | |
Precautionary Statements: | P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P330-P362-P403+P233-P501 | UN#: | |
Hazard Statements: | H302-H312-H332 | Packing Group: | |
GHS Pictogram: |
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
With sodium hydroxide; ethanol; nickel at 120℃; Hydrogenation; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
With hydrogenchloride; acetic acid Erhitzen des Reaktionsprodukts unter Normaldruck; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
With sodium hydroxide at 100℃; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
With hydrogen In ethanol at 200℃; for 2h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
94% | With sodium hydroxide In tetrahydrofuran for 16h; other substrates, other boranes, further base K3PO4; | |
94% | With sodium hydroxide In tetrahydrofuran for 16h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
1: 5% 2: 66% | With sodium hydroxide In tetrahydrofuran |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
87% | With pyridine In dichloromethane at 0℃; for 0.5h; | |
76% | With pyridine at 20℃; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
80% | With sulfuryl dichloride In chloroform at 20℃; for 16h; | |
With diisobutylamine; sulfuryl dichloride |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
88.1% | With potassium carbonate In N,N-dimethyl-formamide at 20℃; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
With dihydrogen peroxide; copper(II) nitrate In phosphate buffer; acetonitrile at 50℃; for 4h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
With potassium carbonate In N,N-dimethyl acetamide Heating; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
63% | Stage #1: isobutylmagnesium bromide With indium(III) chloride In tetrahydrofuran Stage #2: p-Iodophenol With tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran Heating; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
With hydrogenchloride In methanol at 20℃; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
94% | With boron tribromide In dichloromethane at 0 - 20℃; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
Multi-step reaction with 2 steps 1: K2CO3 / dimethylformamide / Heating 2: Pd(PPh3)2Cl2; CuI; Et3N / tetrahydrofuran / 80 °C |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
Multi-step reaction with 3 steps 1: 57 percent / tetrahydrofuran / 0 °C 2: 97 percent / Et3SiH; CF3CO2H / CH2Cl2 / 20 °C 3: 94 percent / BBr3 / CH2Cl2 / 0 - 20 °C |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
Multi-step reaction with 3 steps 1: SO2Cl2; diisobutylamine 2: Cs2CO3 3: Cs2CO3 / dimethylformamide / 65 °C |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
Multi-step reaction with 4 steps 1: SO2Cl2; diisobutylamine 2: Cs2CO3 3: Cs2CO3 / dimethylformamide / 65 °C 4: aq. NaOH / propan-2-ol / 12 h / 70 °C |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
Multi-step reaction with 3 steps 1: SO2Cl2; diisobutylamine 2: Cs2CO3 3: Cs2CO3 / dimethylformamide / 65 °C |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
Multi-step reaction with 4 steps 1: SO2Cl2; diisobutylamine 2: Cs2CO3 3: Cs2CO3 / dimethylformamide / 65 °C 4: aq. NaOH / propan-2-ol / 12 h / 70 °C |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
Multi-step reaction with 3 steps 1.1: NaH / tetrahydrofuran / 4 h / 20 °C 1.2: 85 percent / tetrahydrofuran / 20 °C 2.1: Li; naphthalene / tetrahydrofuran / 2 h / -10 °C 2.2: tetrahydrofuran / 0.5 h / -10 °C 3.1: HCl / methanol / 20 °C |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
Multi-step reaction with 2 steps 1.1: Li; naphthalene / tetrahydrofuran / 2 h / -10 °C 1.2: tetrahydrofuran / 0.5 h / -10 °C 2.1: HCl / methanol / 20 °C |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
Multi-step reaction with 2 steps 1: K2CO3 / N,N-dimethyl-acetamide / Heating 2: mCPBA |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
Multi-step reaction with 3 steps 1: K2CO3 / N,N-dimethyl-acetamide / Heating 2: mCPBA 3: K2CO3 / acetone |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
Multi-step reaction with 4 steps 1: K2CO3 / N,N-dimethyl-acetamide / Heating 2: mCPBA 3: K2CO3 / acetone 4: 1,2-dichloro-benzene / Heating |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
Multi-step reaction with 5 steps 1: K2CO3 / N,N-dimethyl-acetamide / Heating 2: mCPBA 3: K2CO3 / acetone 4: 1,2-dichloro-benzene / Heating 5: H2 / Pd/C |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
Multi-step reaction with 7 steps 1: K2CO3 / N,N-dimethyl-acetamide / Heating 2: mCPBA 3: K2CO3 / acetone 4: 1,2-dichloro-benzene / Heating 5: H2 / Pd/C 6: Cs2CO3 / dimethylformamide / 65 °C 7: SOCl2; pyridine / 20 °C |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
Multi-step reaction with 6 steps 1: K2CO3 / N,N-dimethyl-acetamide / Heating 2: mCPBA 3: K2CO3 / acetone 4: 1,2-dichloro-benzene / Heating 5: H2 / Pd/C 6: Cs2CO3 / dimethylformamide / 65 °C |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
Multi-step reaction with 7 steps 1: K2CO3 / N,N-dimethyl-acetamide / Heating 2: mCPBA 3: K2CO3 / acetone 4: 1,2-dichloro-benzene / Heating 5: H2 / Pd/C 6: Cs2CO3 / dimethylformamide / 65 °C 7: SOCl2; pyridine / 20 °C |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
Multi-step reaction with 6 steps 1: K2CO3 / N,N-dimethyl-acetamide / Heating 2: mCPBA 3: K2CO3 / acetone 4: 1,2-dichloro-benzene / Heating 5: H2 / Pd/C 6: Cs2CO3 / dimethylformamide / 65 °C |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
Multi-step reaction with 9 steps 1: K2CO3 / N,N-dimethyl-acetamide / Heating 2: mCPBA 3: K2CO3 / acetone 4: 1,2-dichloro-benzene / Heating 5: H2 / Pd/C 6: Cs2CO3 / dimethylformamide / 65 °C 7: SOCl2; pyridine / 20 °C 8: NaOAc / ethanol / Heating 9: aq. HCl / ethanol / Heating |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
Multi-step reaction with 8 steps 1.1: K2CO3 / N,N-dimethyl-acetamide / Heating 2.1: mCPBA 3.1: K2CO3 / acetone 4.1: 1,2-dichloro-benzene / Heating 5.1: H2 / Pd/C 6.1: Cs2CO3 / dimethylformamide / 65 °C 7.1: SOCl2; pyridine / 20 °C 8.1: NaOAc / ethanol / Heating 8.2: aq. HCl / ethanol / Heating |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
Multi-step reaction with 8 steps 1: K2CO3 / N,N-dimethyl-acetamide / Heating 2: mCPBA 3: K2CO3 / acetone 4: 1,2-dichloro-benzene / Heating 5: H2 / Pd/C 6: Cs2CO3 / dimethylformamide / 65 °C 7: SOCl2; pyridine / 20 °C 8: NaOAc / ethanol / Heating |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
Multi-step reaction with 3 steps 1: 87 percent / pyridine / CH2Cl2 / 0.5 h / 0 °C 2: 68 percent / K3PO4 / Pd(PPh3)4 / tetrahydrofuran / 18 h / Heating 3: 1.) borane-dimethyl sulfide, 2.) H2O2/NaOH | ||
Multi-step reaction with 3 steps 1: 87 percent / pyridine / CH2Cl2 / 0.5 h / 0 °C 2: 73 percent / K3PO4 / Pd(PPh3)4 / tetrahydrofuran 3: 1.) borane-dimethyl sulfide, 2.) H2O2/NaOH |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
Multi-step reaction with 4 steps 1: 87 percent / pyridine / CH2Cl2 / 0.5 h / 0 °C 2: 68 percent / K3PO4 / Pd(PPh3)4 / tetrahydrofuran / 18 h / Heating 3: 1.) borane-dimethyl sulfide, 2.) H2O2/NaOH 4: 92 percent / O2 / Pd | ||
Multi-step reaction with 4 steps 1: 87 percent / pyridine / CH2Cl2 / 0.5 h / 0 °C 2: 73 percent / K3PO4 / Pd(PPh3)4 / tetrahydrofuran 3: 1.) borane-dimethyl sulfide, 2.) H2O2/NaOH 4: 92 percent / O2 / Pd |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
Multi-step reaction with 2 steps 1: 87 percent / pyridine / CH2Cl2 / 0.5 h / 0 °C 2: 68 percent / K3PO4 / Pd(PPh3)4 / tetrahydrofuran / 18 h / Heating | ||
Multi-step reaction with 2 steps 1: 87 percent / pyridine / CH2Cl2 / 0.5 h / 0 °C 2: 73 percent / K3PO4 / Pd(PPh3)4 / tetrahydrofuran |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
Multi-step reaction with 4 steps 1: 80 percent / SO2Cl2 / CHCl3 / 16 h / 20 °C 2: conc. H2SO4, HOAc / 16 h / 22 °C 3: conc. HCl / ethanol / 1.5 h / Heating 4: 86 percent / H2, NaOH / 5percent Pd/C / H2O / 1551.4 Torr |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
Multi-step reaction with 2 steps 1: 80 percent / SO2Cl2 / CHCl3 / 16 h / 20 °C 2: conc. H2SO4, HOAc / 16 h / 22 °C |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
Multi-step reaction with 5 steps 1: 80 percent / SO2Cl2 / CHCl3 / 16 h / 20 °C 2: conc. H2SO4, HOAc / 16 h / 22 °C 3: conc. HCl / ethanol / 1.5 h / Heating 4: 86 percent / H2, NaOH / 5percent Pd/C / H2O / 1551.4 Torr 5: 56 percent / ICl, 3 N HCl, / H2O / 2 h / 20 °C |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
Multi-step reaction with 3 steps 1: 80 percent / SO2Cl2 / CHCl3 / 16 h / 20 °C 2: conc. H2SO4, HOAc / 16 h / 22 °C 3: conc. HCl / ethanol / 1.5 h / Heating |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
Multi-step reaction with 2 steps 1: Raney nickel; sodium hydroxide; ethanol / 120 °C / 66195.7 Torr / Hydrogenation 2: CrO3; acetic acid; water | ||
Multi-step reaction with 2 steps 1: H2 / Raney-Ni / ethanol / 2 h / 200 °C / 88260.9 Torr 2: CrO3 / pyridine | ||
Multi-step reaction with 2 steps 1: H2 / Raney-Ni / ethanol / 2 h / 200 °C / 88260.9 Torr 2: CrO3 / pyridine |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
Stage #1: tert-butylmagnesium chloride With bis(acetylacetonate)nickel(II); 1-(2-carboxyethyl)-3-mesityl-1H-imidazol-3-ium chloride; lithium tert-butoxide In tetrahydrofuran; diethyl ether at 0℃; for 0.166667h; Inert atmosphere; Stage #2: (4-bromophenoxy)trimethylsilane In tetrahydrofuran; diethyl ether at 0 - 20℃; Inert atmosphere; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
72% | With potassium carbonate In N,N-dimethyl-formamide at 80℃; for 14h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
With dihydrogen peroxide; iron(II) In water at 20℃; | 3. Fenton degradation General procedure: For the Fenton degradation experiment, 10 mL of a Milli Q water sample acidified at pH 2 with 100 µL H2SO4 0.5 mol/L containing 200 ng of each studied anti-inflammatory drug (diclofenac sodium, ibuprofen and ketoprofen) was placed into a 50 mL brown glass bottle. Immediately, 500 µL of Fe2+solution (1 mg/mL Fe2+) and 200 µL of H2O2 (30%) were added into the brown bottle which was kept under magnetic stirring and room temperature for different time intervals in order to perform the degradation process. Because the catalyst (Fe2+) and the oxidant (H2O2) are consumed very fast, these were refreshed at each 30 minutes in the same amounts as it was described previously. To study the Fenton oxidative process efficiency over the selected drugs, different experiments at 30, 60 and 120 minutes were performed. After each Fenton oxidative experiment, the degradation by-products of NAIDs were extracted with organic solvent and analyzed by GC×GC-qMS. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
With dihydrogen peroxide; horseradish peroxidase In aq. phosphate buffer at 24.84℃; for 1h; Sonication; Enzymatic reaction; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
63.7% | Stage #1: ethyl 2-hydroxy-4-methylpyrimidine-5-carboxylate With caesium carbonate In N,N-dimethyl-formamide at 25℃; for 1h; Stage #2: 4-isobutylphenol In N,N-dimethyl-formamide at 75℃; for 1h; | 208.1 [00713] A mixture of ethyl 2-hydroxy-4-methyl-pyrimidine-5-carboxylate (50.0 mg, 0.27mmol), PyAOP (485.5 mg, 1.1 mmol) and Cs2CO3 (179 mg, 0.55 mmol) in N,Ndimethylformamide (5 mL) was stirred at 25 °C for 1 h, then 4-isobutylphenol (164.9 mg, 1.1 mmol) and Cs2CO3 (179 mg, 0.55 mmol) were added. The reaction was stirred in the microwave at 75 °C for 1 h, diluted with water (20 mL) and extracted with EtOAc (25 mL x 3). The combined organic layers were washed with brine (25 mL x 3), dried over Na2SO4 andconcentrated. The residue was purified by prep-TLC (10% EtOAc in petroleum ether) to give ethyl 2-(4-isobutylphenoxy)-4-methylpyrimidine-5-carboxylate (110 mg, 63.7% yield). |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
63 %Spectr. | With Martins sulfurane In tetrahydrofuran; diethyl ether; pentane at -30℃; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
69% | With potassium carbonate In acetonitrile at 0℃; for 2h; Reflux; Inert atmosphere; | 4.1.3 tert-Butyl (2-(N-isopropyl-2-(4-propylphenoxy)acetamido)ethyl)carbamate 10 To a solution of 9 (158mg, 0.57mmol) in anhydrous 5mL MeCN was added K2CO3 (236mg, 1.71mmol) at 0°, followed by 4-propylphenol (86mg, 0.70mmol). The reaction mixture was heated at reflux under nitrogen atmosphere for 2h. After cooling to room temperature, the reaction mixture was concentrated and dissolved with ethyl acetate (10mL), washed with water (10mL×3) and brine (10mL×3). The organic layer was dried over Na2SO4, concentrated under vacuum and purified by SiO2 chromatography (ethyl acetate: petroleum ether=1:5) to afford the compound 10 as a colourless liquid (198mg, 92%). |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
92.6% | With sodium nitrate; nitric acid In water at 20 - 25℃; for 2h; | 7 Example 7, a method for the nitration of isobutyl phenol, the following steps are carried out in sequence: (1), 150 g (1.0 mol) of p-isobutyl phenol was suspended in 301 mL of water,Add 10g of sodium nitrate,Mixing,Slowly add 77 g of fuming nitric acid (concentration 98%, 1.2 mol),The temperature of the reaction system is controlled to not exceed 25 ° C during the dropwise addition.After the completion of the dropwise addition, the reaction was carried out at 20 ° C for 2 h;(2) The reaction solution obtained in the step (1) is allowed to stand at 5 ° C for 1 h.Liquid separation.The lower layer product is separated from o-nitro-p-isobutylphenol;Take 300 mL of the upper dilute nitric acid aqueous solution and 150 g (1.0 mol) of p-isobutyl phenol, and add 71 g of fuming nitric acid (concentration 98%,1.1 mol) recycled nitrification,The temperature of the reaction system is controlled to not exceed 25 ° C during the dropwise addition.After the completion of the dropwise addition, the reaction was carried out at 20 ° C for 2 h.The yield was 89.3%, and the purity was 98.5%;The circulating nitrification yield was 92.6%, and the purity was 98.1%. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
at 454.84℃; for 0.666667h;Kinetics; | Thermolysis was studied in the gas phase in glass capillaries(l = 23-25 mm; dn = 0.95-1.05 mm) made ofPyrex, in which the test substance was placed. Thecapillary was flushed with helium (purity 99.999%)and sealed. The degree of filling was 25-27% of thevolume, which corresponded to a substance mass of 0.8-1.0 mg. Samples were weighted on an ShimadzuAUW 120D analytical balance with an accuracy of104 g. The capillary with the substance was thermostattedin a laboratory pyrolysis furnace, whichensured the accuracy of maintaining the temperature in the isothermal zone to be ±1 K; the device was previouslyreported [13]. The time to reach the isothermalmode after the capillary was placed in the furnace didnot exceed 60 s. The pyrolysis process was completedby quenching in a tube cooled to -15. The thermalstability of 4-TBDPO was studied in the temperaturerange 703-763 K with a step of 5 K. The conversion of4-TBDPO did not exceed 25%; the number of molesin the process increased by no more than 5% |
Tags: 4167-74-2 synthesis path| 4167-74-2 SDS| 4167-74-2 COA| 4167-74-2 purity| 4167-74-2 application| 4167-74-2 NMR| 4167-74-2 COA| 4167-74-2 structure
[ 7727-33-5 ]
4,4',4'',4'''-(Ethane-1,1,2,2-tetrayl)tetraphenol
Similarity: 0.93
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P333 + P313 | IF SKIN irritation or rash occurs: Get medical advice/attention. |
P335 + P334 | Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages. |
P337 + P313 | IF eye irritation persists: Get medical advice/attention. |
P342 + P311 | IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician. |
P370 + P376 | In case of fire: Stop leak if safe to Do so. |
P370 + P378 | In case of fire: |
P370 + P380 | In case of fire: Evacuate area. |
P370 + P380 + P375 | In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion. |
P371 + P380 + P375 | In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion. |
Storage | |
Code | Phrase |
P401 | |
P402 | Store in a dry place. |
P403 | Store in a well-ventilated place. |
P404 | Store in a closed container. |
P405 | Store locked up. |
P406 | Store in corrosive resistant/ container with a resistant inner liner. |
P407 | Maintain air gap between stacks/pallets. |
P410 | Protect from sunlight. |
P411 | |
P412 | Do not expose to temperatures exceeding 50 oC/ 122 oF. |
P413 | |
P420 | Store away from other materials. |
P422 | |
P402 + P404 | Store in a dry place. Store in a closed container. |
P403 + P233 | Store in a well-ventilated place. Keep container tightly closed. |
P403 + P235 | Store in a well-ventilated place. Keep cool. |
P410 + P403 | Protect from sunlight. Store in a well-ventilated place. |
P410 + P412 | Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF. |
P411 + P235 | Keep cool. |
Disposal | |
Code | Phrase |
P501 | Dispose of contents/container to ... |
P502 | Refer to manufacturer/supplier for information on recovery/recycling |
Physical hazards | |
Code | Phrase |
H200 | Unstable explosive |
H201 | Explosive; mass explosion hazard |
H202 | Explosive; severe projection hazard |
H203 | Explosive; fire, blast or projection hazard |
H204 | Fire or projection hazard |
H205 | May mass explode in fire |
H220 | Extremely flammable gas |
H221 | Flammable gas |
H222 | Extremely flammable aerosol |
H223 | Flammable aerosol |
H224 | Extremely flammable liquid and vapour |
H225 | Highly flammable liquid and vapour |
H226 | Flammable liquid and vapour |
H227 | Combustible liquid |
H228 | Flammable solid |
H229 | Pressurized container: may burst if heated |
H230 | May react explosively even in the absence of air |
H231 | May react explosively even in the absence of air at elevated pressure and/or temperature |
H240 | Heating may cause an explosion |
H241 | Heating may cause a fire or explosion |
H242 | Heating may cause a fire |
H250 | Catches fire spontaneously if exposed to air |
H251 | Self-heating; may catch fire |
H252 | Self-heating in large quantities; may catch fire |
H260 | In contact with water releases flammable gases which may ignite spontaneously |
H261 | In contact with water releases flammable gas |
H270 | May cause or intensify fire; oxidizer |
H271 | May cause fire or explosion; strong oxidizer |
H272 | May intensify fire; oxidizer |
H280 | Contains gas under pressure; may explode if heated |
H281 | Contains refrigerated gas; may cause cryogenic burns or injury |
H290 | May be corrosive to metals |
Health hazards | |
Code | Phrase |
H300 | Fatal if swallowed |
H301 | Toxic if swallowed |
H302 | Harmful if swallowed |
H303 | May be harmful if swallowed |
H304 | May be fatal if swallowed and enters airways |
H305 | May be harmful if swallowed and enters airways |
H310 | Fatal in contact with skin |
H311 | Toxic in contact with skin |
H312 | Harmful in contact with skin |
H313 | May be harmful in contact with skin |
H314 | Causes severe skin burns and eye damage |
H315 | Causes skin irritation |
H316 | Causes mild skin irritation |
H317 | May cause an allergic skin reaction |
H318 | Causes serious eye damage |
H319 | Causes serious eye irritation |
H320 | Causes eye irritation |
H330 | Fatal if inhaled |
H331 | Toxic if inhaled |
H332 | Harmful if inhaled |
H333 | May be harmful if inhaled |
H334 | May cause allergy or asthma symptoms or breathing difficulties if inhaled |
H335 | May cause respiratory irritation |
H336 | May cause drowsiness or dizziness |
H340 | May cause genetic defects |
H341 | Suspected of causing genetic defects |
H350 | May cause cancer |
H351 | Suspected of causing cancer |
H360 | May damage fertility or the unborn child |
H361 | Suspected of damaging fertility or the unborn child |
H361d | Suspected of damaging the unborn child |
H362 | May cause harm to breast-fed children |
H370 | Causes damage to organs |
H371 | May cause damage to organs |
H372 | Causes damage to organs through prolonged or repeated exposure |
H373 | May cause damage to organs through prolonged or repeated exposure |
Environmental hazards | |
Code | Phrase |
H400 | Very toxic to aquatic life |
H401 | Toxic to aquatic life |
H402 | Harmful to aquatic life |
H410 | Very toxic to aquatic life with long-lasting effects |
H411 | Toxic to aquatic life with long-lasting effects |
H412 | Harmful to aquatic life with long-lasting effects |
H413 | May cause long-lasting harmful effects to aquatic life |
H420 | Harms public health and the environment by destroying ozone in the upper atmosphere |
Sorry,this product has been discontinued.
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