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Chemical Structure| 42417-76-5 Chemical Structure| 42417-76-5

Structure of 42417-76-5

Chemical Structure| 42417-76-5

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Product Details of [ 42417-76-5 ]

CAS No. :42417-76-5
Formula : C20H29NO6
M.W : 379.45
SMILES Code : O=C(OC(C)(C)C)C[C@@H](C(OC(C)(C)C)=O)NC(OCC1=CC=CC=C1)=O
MDL No. :MFCD00270579

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Application In Synthesis of [ 42417-76-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 42417-76-5 ]

[ 42417-76-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 42417-76-5 ]
  • [ 1791-13-5 ]
YieldReaction ConditionsOperation in experiment
80% Pd/C (10%, 830 mg, 10% w/w) was added to a solution of Cbz-Asp(OtBu)-OtBu 18 (8.25 g, 21.8 mmol) and ammonium formate (34.3 g, 0.54 mol) in ethanol (20 mL) and the suspension stirred overnight at room temperature. The suspension was filtered through Celite and the solvent removed under reduced pressure. The resultant residue was uptaken in ethyl acetate and cooled to 0 C and a saturated solution of HCl in ethyl acetate was added dropwise and the solution stirred for 15 min. The precipitated solid was filtered, washed with cold ethyl acetate and dried under vacuum to give NH2-Asp(OtBu)-OtBu hydrochloride, 16 (4.28 g, 17.4 mmol, 80%) as a white solid, which was used without any further purification
 

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