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Chemical Structure| 43090-97-7 Chemical Structure| 43090-97-7

Structure of 43090-97-7

Chemical Structure| 43090-97-7

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Product Details of [ 43090-97-7 ]

CAS No. :43090-97-7
Formula : C8H8N2O4S
M.W : 228.22
SMILES Code : [O-][N+](C1=CC=C(S(=O)(N2CC2)=O)C=C1)=O
MDL No. :MFCD27950742

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Application In Synthesis of [ 43090-97-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 43090-97-7 ]

[ 43090-97-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 43090-97-7 ]
  • [ 42303-42-4 ]
  • 1-[2-(4-nitro-benzenesulfonylamino)-ethylamino]-cyclopropane carboxylic acid ethyl ester [ No CAS ]
YieldReaction ConditionsOperation in experiment
61% With sodium carbonate; In acetonitrile; for 3h;Reflux; A mixture of the Ns-aziridine Ig (6.89g, 30.2mmol), <strong>[42303-42-4]1-amino-cyclopropanecarboxylic acid ethyl ester hydrochloride</strong> (5.00g, 30.2mmol) and Na2C03 (3.20g, 30.2mmol) in dry acetonitrile (120ml) was heated to reflux for 3h. The mixture was cooled, filtered and evaporated. The residue was purified by column chromatography (Si02, 5% acetone to 10% acetone in DCM) to afford the title compound as a pale yellow solid (6.58g, 61%). :H NMR (400 MHz, DMSO-d6) delta 8.41 (d, J = 8.8 Hz, 2H), 8.04 (d, J = 8.8 Hz, 2H), 7.84 (br s, 1H), 4.02 (q, J = 7.1 Hz, 2H), 2.84 (s, 2H), 2.72-2.58 (m, 3H), 1.14 (t, J = 7.1 Hz, 3H), 1.07 (dd, J = 7.0, 3.7 Hz, 2H), 0.81 (dd, J = 7.0, 3.8 Hz, 2H).
 

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