There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.
Type | HazMat fee for 500 gram (Estimated) |
Excepted Quantity | USD 0.00 |
Limited Quantity | USD 15-60 |
Inaccessible (Haz class 6.1), Domestic | USD 80+ |
Inaccessible (Haz class 6.1), International | USD 150+ |
Accessible (Haz class 3, 4, 5 or 8), Domestic | USD 100+ |
Accessible (Haz class 3, 4, 5 or 8), International | USD 200+ |
Purity | Size | Price | VIP Price | USA Stock *0-1 Day | Global Stock *5-7 Days | Quantity | |||||
{[ item.p_purity ]} | {[ item.pr_size ]} |
{[ getRatePrice(item.pr_usd, 1,1) ]} {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate) ]} |
{[ getRatePrice(item.pr_usd, 1,1) ]} | Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate) ]} {[ getRatePrice(item.pr_usd,1,item.mem_rate) ]} | {[ item.pr_usastock ]} | Inquiry - | {[ item.pr_chinastock ]} | Inquiry - |
* Storage: {[proInfo.prStorage]}
CAS No. : | 43112-38-5 | MDL No. : | MFCD00010197 |
Formula : | C6H13NO2Si | Boiling Point : | - |
Linear Structure Formula : | - | InChI Key : | AUKCYOUETBBMFV-UHFFFAOYSA-N |
M.W : | 159.26 | Pubchem ID : | 123514 |
Synonyms : |
|
Num. heavy atoms : | 10 |
Num. arom. heavy atoms : | 0 |
Fraction Csp3 : | 0.83 |
Num. rotatable bonds : | 1 |
Num. H-bond acceptors : | 2.0 |
Num. H-bond donors : | 0.0 |
Molar Refractivity : | 45.19 |
TPSA : | 29.54 Ų |
GI absorption : | High |
BBB permeant : | Yes |
P-gp substrate : | No |
CYP1A2 inhibitor : | No |
CYP2C19 inhibitor : | No |
CYP2C9 inhibitor : | No |
CYP2D6 inhibitor : | No |
CYP3A4 inhibitor : | No |
Log Kp (skin permeation) : | -6.33 cm/s |
Log Po/w (iLOGP) : | 2.01 |
Log Po/w (XLOGP3) : | 1.32 |
Log Po/w (WLOGP) : | 0.89 |
Log Po/w (MLOGP) : | 0.41 |
Log Po/w (SILICOS-IT) : | -0.62 |
Consensus Log Po/w : | 0.8 |
Lipinski : | 0.0 |
Ghose : | None |
Veber : | 0.0 |
Egan : | 0.0 |
Muegge : | 1.0 |
Bioavailability Score : | 0.55 |
Log S (ESOL) : | -1.59 |
Solubility : | 4.07 mg/ml ; 0.0255 mol/l |
Class : | Very soluble |
Log S (Ali) : | -1.54 |
Solubility : | 4.58 mg/ml ; 0.0288 mol/l |
Class : | Very soluble |
Log S (SILICOS-IT) : | -0.93 |
Solubility : | 18.8 mg/ml ; 0.118 mol/l |
Class : | Soluble |
PAINS : | 0.0 alert |
Brenk : | 1.0 alert |
Leadlikeness : | 1.0 |
Synthetic accessibility : | 2.67 |
Signal Word: | Danger | Class: | 3 |
Precautionary Statements: | P210-P280-P370+P378-P403+P235-P501 | UN#: | 1993 |
Hazard Statements: | H225 | Packing Group: | Ⅲ |
GHS Pictogram: |
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
90% | With triethylamine In butanone at 20℃; for 1h; | |
90% | With triethylamine In butanone r.t. to 40-45 deg C, 20 deg C, 1 h; | |
With triethylamine In tetrahydrofuran |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
90% | With 18-crown-6 ether; potassium carbonate at 100℃; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
95% | at 0℃; for 0.0166667h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
97% | at 15℃; for 0.0333333h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
93% | In tetrachloromethane at 77℃; for 0.25h; | |
With triethylamine In dichloromethane for 0.5h; Ambient temperature; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
95% | at 15℃; for 0.0333333h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
98% | at 0℃; for 0.0333333h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
80% | at 40℃; for 1h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
83% | for 0.166667h; Ambient temperature; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
90% | In tetrachloromethane at 77℃; for 0.333333h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
90% | at 20℃; for 0.0166667h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
With triethylamine In dichloromethane for 0.5h; Ambient temperature; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
With triethylamine In dichloromethane for 0.5h; Ambient temperature; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
97% | at 20℃; for 0.166667h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
95% | In tetrachloromethane at 77℃; for 0.25h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
95% | In tetrachloromethane at 77℃; for 0.25h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
83% | at 20℃; for 0.25h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
80% | In hexane at 40℃; for 2.5h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
98% | at 40℃; for 0.25h; | |
80% | for 0.0333333h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
91% | at 20℃; for 0.0166667h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
With triethylamine In dichloromethane for 0.5h; Ambient temperature; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
With triethylamine In dichloromethane for 0.5h; Ambient temperature; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
74% | In tetrachloromethane at 15℃; for 0.25h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
80% | In tetrachloromethane for 1.5h; Ambient temperature; | |
With triethylamine In dichloromethane for 0.5h; Ambient temperature; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
80% | at 20℃; for 0.666667h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
97% | at 23℃; for 0.05h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
In tetrahydrofuran for 0.5h; Ambient temperature; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
96% | at 80℃; for 192h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
In dichloromethane at 20℃; for 2h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
95% | at 15℃; for 0.00833333h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
With TEA In dichloromethane |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
90% | In tetrachloromethane at 77℃; for 0.25h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
84% | at 15℃; for 0.25h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
90% | at 20℃; for 0.166667h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
92% | at 15℃; for 0.00416667h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
94% | at 20℃; for 0.05h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
95% | In tetrachloromethane at 77℃; for 0.333333h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
93% | at 15℃; for 0.0333333h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
94% | In tetrachloromethane at 77℃; for 0.333333h; | |
In dichloromethane for 0.5h; Ambient temperature; | ||
at 100℃; for 0.5h; Inert atmosphere; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
93% | for 0.166667h; Ambient temperature; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
88% | at 20℃; for 0.583333h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
at 15℃; for 0.166667h; Yield given. Yields of byproduct given; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
91% | at 15℃; for 0.05h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
93% | In tetrachloromethane at 77℃; for 0.25h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
99% | at 0℃; for 0.0166667h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
95% | In tetrachloromethane at 77℃; for 0.333333h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
96% | at 0℃; for 0.333333h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
86% | at 0℃; for 0.5h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
With triethylamine In dichloromethane for 0.5h; Ambient temperature; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
94% | at 20℃; for 0.0166667h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
95% | at 15℃; for 0.0833333h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
96% | In tetrachloromethane at 77℃; for 0.333333h; | |
With triethylamine In dichloromethane for 0.5h; Ambient temperature; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
98% | at 20℃; for 0.583333h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
86% | for 0.166667h; Ambient temperature; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
92% | for 0.166667h; Ambient temperature; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
98% | In hexane at 20℃; for 0.0166667h; other alcohols, vari. of time, temperature, with or without solvent; | |
98% | In hexane at 20℃; for 0.0166667h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
91% | at 15℃; for 0.00416667h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
95% | In hexane at 0℃; for 0.0166667h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
97% | In hexane at 20℃; for 0.0833333h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
With triethylamine In dichloromethane for 0.5h; Ambient temperature; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
With triethylamine In dichloromethane for 0.5h; Ambient temperature; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
97% | at 15℃; for 0.0333333h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
87% | at 15℃; for 0.0333333h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
90% | In tetrachloromethane at 77℃; for 0.25h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
80% | With dinitrogen pentoxide In dichloromethane at 0℃; for 0.7h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
100% | With trifluorormethanesulfonic acid Ambient temperature; | |
100% | With trifluorormethanesulfonic acid at 20℃; for 1h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
64.3% | With potassium trimethylsilonate In tetrahydrofuran at 100℃; for 2h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
98% | With trifluorormethanesulfonic acid at 20℃; for 1h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
99% | With trifluorormethanesulfonic acid at 20℃; for 1h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
With potassium trimethylsilonate In tetrahydrofuran at 95℃; for 3h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
53% | With potassium trimethylsilonate In tetrahydrofuran at 95℃; for 3h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
94% | With trimethylsilyl trifluoromethanesulfonate In toluene at 0 - 20℃; for 4.5h; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
(c) (R)-3-[3-(2-Nitro-1H-imidazol-1-yl)-2-[(trimethylsilyl)oxy]propyl]-2-oxazolidinone Reaction of 8.46 g (50 mmole) of (R)-(+)-2-nitro-1-(2-oxiranylmethyl) -1H-imidazole, 9.4 mL (59.8 mmole) of 3-trimethylsilyl-2-oxazolidinone, and 64 mg of <strong>[10519-96-7]potassium trimethylsilanolate</strong> followed by workup as described in Example 2(c) below gives 8.04 g of pure product, mp 98-100 C.; [alpha]D25 =14.54 [c1, methanol]. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
In tetrahydrofuran; tert-butyl methyl ether; cyclohexane; ethyl acetate; | (c) (S)-3-[3-(2-Nitro-1H-imidazol-1-yl)-2-[(trimethylsilyl)oxy]propyl]-2-oxazolidinone Under a brisk stream of dry nitrogen, a vigorously stirring mixture of 40.3 mL (256 mmole) of 3-trimethylsilyl-2-oxazolidinone and 274 mg (2.1 mmole) of <strong>[10519-96-7]potassium trimethylsilanolate</strong> is heated to 95 C. To the solution is added over 10 minutes a solution of 36.15 g (214 mmole) of (S)-(-)-2 -nitro-1-(2-oxiranylmethyl)-1H-imidazole in 26 mL of dry tetrahydrofuran during which an opening in the flask allows evaporation of solvent. The addition funnel is rinsed with 5 mL of solvent, and the flask is kept open for an additional 15 minutes. After heating at 95 C. for a total of 1.5 hours, 3.4 mL of additional 3-trimethylsilyl-2-oxazolidinone is added to the solution. The mixture is heated for an additional 1.5 hours then concentrated at 0.8 mm/50 C./16 hours to give an oil that is dissolved in 100 mL of 2:1 ethyl acetate:cyclohexane. The solution is loaded onto a column containing an 8*16 cm pad of silica gel (230-400 mesh). The column is eluted with ~5 L of 2:1 ethyl acetate: cyclohexane. Product fractions are combined and concentrated first at 20 mm, then at 0.8 mm to give 71.45 g of an oil that solidifies on standing. The solids are diluted with 200 mL of tert-butyl methyl ether, and the suspension is refluxed for 45 minutes, cooled, and filtered. The solids are washed sparingly with tert-butyl methyl ether and dried to leave 37.18 g of pure product as a light yellow solid, mp 98-100 C.; [alpha]D25 =+15.4 [c1, methanol]. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
48% | In N-Bromosuccinimide; dichloromethane | 73 EXAMPLE 73 EXAMPLE 73 A mixture consisting of 753 mg (2.16 mmoles) of 3-methyl-7-phenylacetamido-3-cephem-4-carboxylic acid-1-oxide, 785 mg (4.94 mmoles) of N-trimethylsilyl-2-oxazolidinone and 70 ml of dichloromethane was refluxed for 2 hours, after which a clear, almost colorless solution was obtained. This was cooled in an ice-bath and bromination was carried out in half an hour using 624.5 mg (3.51 mmoles) of N-bromosuccinimide as the brominating agent to obtain a yield of 48% of trimethylsilyl 3-bromomethyl-7-phenylacetamido-3-cephem-4-carboxylate-1-oxide. |
46% | In N-Bromosuccinimide; dichloromethane; aminosulfonic acid | 87 EXAMPLE 87 EXAMPLE 87 The clear solution obtained after refluxing a mixture consisting of 40 ml of dichloromethane, 608.7 mg (1.75 mmoles) of 3-methyl-7-phenylacetamido-3-cephem-4-carboxylic acid-1-oxide and 450 mg (2.83 mmoles) of N-trimethylsilyl-2-oxazolidinone for two hours was cooled in an ice-bath and 0.1 g of amidosulfonic acid (1 mmole) was added thereto. Bromination was carried out in half an hour using 469 mg (2.63 mmoles) of N-bromosuccinimide as the brominating agent to obtain a 46% yield of trimethylsilyl 3-bromomethyl-7-phenylacetamido-3-cephem-4-carboxylate-1-oxide. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
With trifluorormethanesulfonic acid In tetrachloromethane; hydroxymethylenemalonic acid dimethyl ester | 6.B B. B. Dimethyl trimethylsilyloxymethylenemalonate (SMMM) To a stirred, cooled (0-5°C) suspension of TMSO (16.0 g; 0.1 mole) in dimethyl hydroxymethylenemalonate (16.0 g; 0.1 mole) trifluoromethanesulfonic acid (0.5 ml) is added. The stirring is continued until room temperature is reached (20-25°C), and the carbon tetrachloride (100 ml) is added and the 2-oxazolidinone is filtered off. Vacuum elimination of the solvent from the filtered solution affords as an oil the title compound (SMMM) in a virtually quantitative yield (23.0 g). |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
With trifluorormethanesulfonic acid In tetrachloromethane | 6.C C. C. Ditrimethylsilyl trimethylsilyloxymethylenemalonate (SMMS) A solution of TMSO (48.0 g; 0.3 mole), formylmalonic acid (13.21 g; 0.1 mole) and trifluoromethanesulfonic acid (0.5 ml) in carbon tetrachloride (100 ml) is refluxed gently and stirred during a short time (30 min.). Working up the reaction mass as in the preceding cases, the title compound (SMMS) is obtained as an oil in a virtually quantitative yield (34.3 g). It is kept from moisture. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
95% | With trifluorormethanesulfonic acid In dichloromethane at 20℃; for 0.5h; Inert atmosphere; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
1: 55% 2: 20% | With trimethylsilyl trifluoromethanesulfonate In 1,2-dichloro-ethane at 20℃; for 24h; Inert atmosphere; Overall yield = 75 %; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
1: 54% 2: 28% | With trimethylsilyl trifluoromethanesulfonate In 1,2-dichloro-ethane at 20℃; for 24h; Inert atmosphere; Overall yield = 82 %; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
93% | With trifluorormethanesulfonic acid at 0 - 20℃; for 2h; | |
93% | With trifluorormethanesulfonic acid at 0 - 20℃; for 2h; | |
93% | With trifluorormethanesulfonic acid at 0 - 20℃; for 2h; Inert atmosphere; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
With tetrabutyl ammonium fluoride; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; bis(dibenzylideneacetone)-palladium(0) In tetrahydrofuran; 1,4-dioxane at 110℃; Inert atmosphere; | 131 3-{ 4-[1-methyl-4-(1-methylpiperidin-4-yloxy )-9, 1 Odihydro-4H -3,1 Oa-diaza-benzo[ f]azulen-2-yl]-phenyI} -oxazolidin-2-one In a screw-capped vial are added 2-( 4-bromophenyl)-1-methyl-4-(1-methylpiperidin-4-yloxy )-9, 1 O-dihydro-4H -3,lOa-diaza-benzo[f]azulene (example 122A) (50 mg, 0.107mmole), Pd(dba)2 (4.9 mg, 5.3 f.tmole), Xantphos (6.2 mg,10.6 f.tmole), 1,4-dioxane (0.7 mL) and N-trimethylsilylox-azolidonone (25 f.LL, 0.16 mmoles ). The flask is evacuated andfilled with argon. Bu4NF Min THF (160 f.LL, 0.16 mmole) isadded and the reaction mixture is heated at 11 oo C. overnight.Water is added and pH adjusted to 10 with a few drops of 1 NNaOH. The aqueous phase is extracted three times with50 CH2Cl2 . The organic phase is dried over magnesium sulphate,filtered and the solvent is removed under reduced pressure.The residue is pre-purified by silica gel chromatographyusing (CH2Cl2 :MeOH:NH40H) with a gradient from (100:0:0) to (95:5:0.5). The residue is submitted to a preparative55 TLC eluting with (CH2Cl2 :MeOH:NH40H) (92.5:7.5:0.75)to give 3-{ 4-[1-methyl-4-(1-methylpiperidin-4-yloxy)-9,1 Odihydro-4H -3,1 Oa-diaza-benzo[ f]azulen-2-yl]-phenyl }-oxazolidin-2-one melting at 214° C. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
62% | With tetrabutylammonium hydrogen bifluoride In acetonitrile at 0 - 20℃; for 24h; Inert atmosphere; |
Tags: 43112-38-5 synthesis path| 43112-38-5 SDS| 43112-38-5 COA| 43112-38-5 purity| 43112-38-5 application| 43112-38-5 NMR| 43112-38-5 COA| 43112-38-5 structure
Precautionary Statements-General | |
Code | Phrase |
P101 | If medical advice is needed,have product container or label at hand. |
P102 | Keep out of reach of children. |
P103 | Read label before use |
Prevention | |
Code | Phrase |
P201 | Obtain special instructions before use. |
P202 | Do not handle until all safety precautions have been read and understood. |
P210 | Keep away from heat/sparks/open flames/hot surfaces. - No smoking. |
P211 | Do not spray on an open flame or other ignition source. |
P220 | Keep/Store away from clothing/combustible materials. |
P221 | Take any precaution to avoid mixing with combustibles |
P222 | Do not allow contact with air. |
P223 | Keep away from any possible contact with water, because of violent reaction and possible flash fire. |
P230 | Keep wetted |
P231 | Handle under inert gas. |
P232 | Protect from moisture. |
P233 | Keep container tightly closed. |
P234 | Keep only in original container. |
P235 | Keep cool |
P240 | Ground/bond container and receiving equipment. |
P241 | Use explosion-proof electrical/ventilating/lighting/equipment. |
P242 | Use only non-sparking tools. |
P243 | Take precautionary measures against static discharge. |
P244 | Keep reduction valves free from grease and oil. |
P250 | Do not subject to grinding/shock/friction. |
P251 | Pressurized container: Do not pierce or burn, even after use. |
P260 | Do not breathe dust/fume/gas/mist/vapours/spray. |
P261 | Avoid breathing dust/fume/gas/mist/vapours/spray. |
P262 | Do not get in eyes, on skin, or on clothing. |
P263 | Avoid contact during pregnancy/while nursing. |
P264 | Wash hands thoroughly after handling. |
P265 | Wash skin thouroughly after handling. |
P270 | Do not eat, drink or smoke when using this product. |
P271 | Use only outdoors or in a well-ventilated area. |
P272 | Contaminated work clothing should not be allowed out of the workplace. |
P273 | Avoid release to the environment. |
P280 | Wear protective gloves/protective clothing/eye protection/face protection. |
P281 | Use personal protective equipment as required. |
P282 | Wear cold insulating gloves/face shield/eye protection. |
P283 | Wear fire/flame resistant/retardant clothing. |
P284 | Wear respiratory protection. |
P285 | In case of inadequate ventilation wear respiratory protection. |
P231 + P232 | Handle under inert gas. Protect from moisture. |
P235 + P410 | Keep cool. Protect from sunlight. |
Response | |
Code | Phrase |
P301 | IF SWALLOWED: |
P304 | IF INHALED: |
P305 | IF IN EYES: |
P306 | IF ON CLOTHING: |
P307 | IF exposed: |
P308 | IF exposed or concerned: |
P309 | IF exposed or if you feel unwell: |
P310 | Immediately call a POISON CENTER or doctor/physician. |
P311 | Call a POISON CENTER or doctor/physician. |
P312 | Call a POISON CENTER or doctor/physician if you feel unwell. |
P313 | Get medical advice/attention. |
P314 | Get medical advice/attention if you feel unwell. |
P315 | Get immediate medical advice/attention. |
P320 | |
P302 + P352 | IF ON SKIN: wash with plenty of soap and water. |
P321 | |
P322 | |
P330 | Rinse mouth. |
P331 | Do NOT induce vomiting. |
P332 | IF SKIN irritation occurs: |
P333 | If skin irritation or rash occurs: |
P334 | Immerse in cool water/wrap n wet bandages. |
P335 | Brush off loose particles from skin. |
P336 | Thaw frosted parts with lukewarm water. Do not rub affected area. |
P337 | If eye irritation persists: |
P338 | Remove contact lenses, if present and easy to do. Continue rinsing. |
P340 | Remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P341 | If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P342 | If experiencing respiratory symptoms: |
P350 | Gently wash with plenty of soap and water. |
P351 | Rinse cautiously with water for several minutes. |
P352 | Wash with plenty of soap and water. |
P353 | Rinse skin with water/shower. |
P360 | Rinse immediately contaminated clothing and skin with plenty of water before removing clothes. |
P361 | Remove/Take off immediately all contaminated clothing. |
P362 | Take off contaminated clothing and wash before reuse. |
P363 | Wash contaminated clothing before reuse. |
P370 | In case of fire: |
P371 | In case of major fire and large quantities: |
P372 | Explosion risk in case of fire. |
P373 | DO NOT fight fire when fire reaches explosives. |
P374 | Fight fire with normal precautions from a reasonable distance. |
P376 | Stop leak if safe to do so. Oxidising gases (section 2.4) 1 |
P377 | Leaking gas fire: Do not extinguish, unless leak can be stopped safely. |
P378 | |
P380 | Evacuate area. |
P381 | Eliminate all ignition sources if safe to do so. |
P390 | Absorb spillage to prevent material damage. |
P391 | Collect spillage. Hazardous to the aquatic environment |
P301 + P310 | IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
P301 + P312 | IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. |
P301 + P330 + P331 | IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. |
P302 + P334 | IF ON SKIN: Immerse in cool water/wrap in wet bandages. |
P302 + P350 | IF ON SKIN: Gently wash with plenty of soap and water. |
P303 + P361 + P353 | IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. |
P304 + P312 | IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell. |
P304 + P340 | IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. |
P304 + P341 | IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P305 + P351 + P338 | IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
P306 + P360 | IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes. |
P307 + P311 | IF exposed: call a POISON CENTER or doctor/physician. |
P308 + P313 | IF exposed or concerned: Get medical advice/attention. |
P309 + P311 | IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician. |
P332 + P313 | IF SKIN irritation occurs: Get medical advice/attention. |
P333 + P313 | IF SKIN irritation or rash occurs: Get medical advice/attention. |
P335 + P334 | Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages. |
P337 + P313 | IF eye irritation persists: Get medical advice/attention. |
P342 + P311 | IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician. |
P370 + P376 | In case of fire: Stop leak if safe to Do so. |
P370 + P378 | In case of fire: |
P370 + P380 | In case of fire: Evacuate area. |
P370 + P380 + P375 | In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion. |
P371 + P380 + P375 | In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion. |
Storage | |
Code | Phrase |
P401 | |
P402 | Store in a dry place. |
P403 | Store in a well-ventilated place. |
P404 | Store in a closed container. |
P405 | Store locked up. |
P406 | Store in corrosive resistant/ container with a resistant inner liner. |
P407 | Maintain air gap between stacks/pallets. |
P410 | Protect from sunlight. |
P411 | |
P412 | Do not expose to temperatures exceeding 50 oC/ 122 oF. |
P413 | |
P420 | Store away from other materials. |
P422 | |
P402 + P404 | Store in a dry place. Store in a closed container. |
P403 + P233 | Store in a well-ventilated place. Keep container tightly closed. |
P403 + P235 | Store in a well-ventilated place. Keep cool. |
P410 + P403 | Protect from sunlight. Store in a well-ventilated place. |
P410 + P412 | Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF. |
P411 + P235 | Keep cool. |
Disposal | |
Code | Phrase |
P501 | Dispose of contents/container to ... |
P502 | Refer to manufacturer/supplier for information on recovery/recycling |
Physical hazards | |
Code | Phrase |
H200 | Unstable explosive |
H201 | Explosive; mass explosion hazard |
H202 | Explosive; severe projection hazard |
H203 | Explosive; fire, blast or projection hazard |
H204 | Fire or projection hazard |
H205 | May mass explode in fire |
H220 | Extremely flammable gas |
H221 | Flammable gas |
H222 | Extremely flammable aerosol |
H223 | Flammable aerosol |
H224 | Extremely flammable liquid and vapour |
H225 | Highly flammable liquid and vapour |
H226 | Flammable liquid and vapour |
H227 | Combustible liquid |
H228 | Flammable solid |
H229 | Pressurized container: may burst if heated |
H230 | May react explosively even in the absence of air |
H231 | May react explosively even in the absence of air at elevated pressure and/or temperature |
H240 | Heating may cause an explosion |
H241 | Heating may cause a fire or explosion |
H242 | Heating may cause a fire |
H250 | Catches fire spontaneously if exposed to air |
H251 | Self-heating; may catch fire |
H252 | Self-heating in large quantities; may catch fire |
H260 | In contact with water releases flammable gases which may ignite spontaneously |
H261 | In contact with water releases flammable gas |
H270 | May cause or intensify fire; oxidizer |
H271 | May cause fire or explosion; strong oxidizer |
H272 | May intensify fire; oxidizer |
H280 | Contains gas under pressure; may explode if heated |
H281 | Contains refrigerated gas; may cause cryogenic burns or injury |
H290 | May be corrosive to metals |
Health hazards | |
Code | Phrase |
H300 | Fatal if swallowed |
H301 | Toxic if swallowed |
H302 | Harmful if swallowed |
H303 | May be harmful if swallowed |
H304 | May be fatal if swallowed and enters airways |
H305 | May be harmful if swallowed and enters airways |
H310 | Fatal in contact with skin |
H311 | Toxic in contact with skin |
H312 | Harmful in contact with skin |
H313 | May be harmful in contact with skin |
H314 | Causes severe skin burns and eye damage |
H315 | Causes skin irritation |
H316 | Causes mild skin irritation |
H317 | May cause an allergic skin reaction |
H318 | Causes serious eye damage |
H319 | Causes serious eye irritation |
H320 | Causes eye irritation |
H330 | Fatal if inhaled |
H331 | Toxic if inhaled |
H332 | Harmful if inhaled |
H333 | May be harmful if inhaled |
H334 | May cause allergy or asthma symptoms or breathing difficulties if inhaled |
H335 | May cause respiratory irritation |
H336 | May cause drowsiness or dizziness |
H340 | May cause genetic defects |
H341 | Suspected of causing genetic defects |
H350 | May cause cancer |
H351 | Suspected of causing cancer |
H360 | May damage fertility or the unborn child |
H361 | Suspected of damaging fertility or the unborn child |
H361d | Suspected of damaging the unborn child |
H362 | May cause harm to breast-fed children |
H370 | Causes damage to organs |
H371 | May cause damage to organs |
H372 | Causes damage to organs through prolonged or repeated exposure |
H373 | May cause damage to organs through prolonged or repeated exposure |
Environmental hazards | |
Code | Phrase |
H400 | Very toxic to aquatic life |
H401 | Toxic to aquatic life |
H402 | Harmful to aquatic life |
H410 | Very toxic to aquatic life with long-lasting effects |
H411 | Toxic to aquatic life with long-lasting effects |
H412 | Harmful to aquatic life with long-lasting effects |
H413 | May cause long-lasting harmful effects to aquatic life |
H420 | Harms public health and the environment by destroying ozone in the upper atmosphere |
Sorry,this product has been discontinued.
Home
* Country/Region
* Quantity Required :
* Cat. No.:
* CAS No :
* Product Name :
* Additional Information :