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Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
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Inaccessible (Haz class 6.1), International USD 150+
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Chemical Structure| 43219-50-7 Chemical Structure| 43219-50-7

Structure of 43219-50-7

Chemical Structure| 43219-50-7

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Product Details of [ 43219-50-7 ]

CAS No. :43219-50-7
Formula : C4H7NO
M.W : 85.11
SMILES Code : COCC[N+]#[C-]
MDL No. :MFCD06200529

Safety of [ 43219-50-7 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301-H311-H331-H334
Precautionary Statements:P261-P264-P270-P271-P280-P285-P302+P352-P304+P340-P310-P330-P361-P403+P233-P405-P501
Class:6.1
UN#:2810
Packing Group:

Application In Synthesis of [ 43219-50-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 43219-50-7 ]

[ 43219-50-7 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 42182-27-4 ]
  • [ 43219-50-7 ]
  • [ 66-25-1 ]
  • C16H22N4O [ No CAS ]
YieldReaction ConditionsOperation in experiment
With acetic acid; In methanol; at 20℃; To a solution of 4-cyano-2-aminopyridine (0.27 mg, 2.24 mmol) in MeOH (7.45 mL) was added the aldehyde (2.24 mmol), the isonitrile (2.24 mmol) and AcOH (260 muL, 4.48 mmol) at room temp. The reaction was stirred overnight and monitored by EPO <DP n="72"/>LCMS/TLC. When the reaction has completed, 1Lambda/ hydrochloric acid was added till pH ~ 1. The mixture was then evaporated. Saturated sodium bicarbonate solution was then added and ethyl acetate was used to extract. The combined organic extracts were then washed with brine, before drying in anhydrous sodium sulfate. The mixture was then filtered and concentrated. The crude product was used immediately without further purification (Tetrahedron Letters, 1998, 39, 3635).
  • 2
  • [ 14779-17-0 ]
  • [ 43219-50-7 ]
  • [ 100-10-7 ]
  • [ 1207835-38-8 ]
 

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