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Chemical Structure| 435271-24-2 Chemical Structure| 435271-24-2

Structure of 435271-24-2

Chemical Structure| 435271-24-2

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Product Details of [ 435271-24-2 ]

CAS No. :435271-24-2
Formula : C8H9N3
M.W : 147.18
SMILES Code : N#CC1=CN=CC=C1N(C)C

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Application In Synthesis of [ 435271-24-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 435271-24-2 ]

[ 435271-24-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 154237-70-4 ]
  • [ 124-40-3 ]
  • [ 435271-24-2 ]
YieldReaction ConditionsOperation in experiment
With potassium carbonate; at 40℃; for 2h; Into a 20 mL vial were added dimethylamine (295.63 mg, 6.557 mmol, 2.00 equiv) , <strong>[154237-70-4]4-bromopyridine-3-carbonitrile</strong> (600 mg, 3.279 mmol, 1 equiv) and K 2CO 3 (1.36 g, 9.836 mmol, 3.00 equiv) at room temperature. The resulting mixture was stirred for 2 h at 40. The resulting mixture was filtered, the filter cake was washed with DCM (2x20 mL) . The filtrate was concentrated under reduced pressure. The residue was purified by Prep-TLC (EtOAc) to afford 4- (dimethylamino) pyridine-3-carbonitrile (470mg, 97.40%) as an off-white solid (crude) . 1H-NMR (400 MHz, CDCl 3) delta 3.26 (6H, s) , 6.55 (1H, d) , 8.23 (1H, d) , 8.47 (1H, s)
 

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