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Chemical Structure| 439692-55-4 Chemical Structure| 439692-55-4

Structure of 439692-55-4

Chemical Structure| 439692-55-4

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Product Details of [ 439692-55-4 ]

CAS No. :439692-55-4
Formula : C10H11ClN2S
M.W : 226.73
SMILES Code : CC(C1=CC2=C(Cl)N=CN=C2S1)(C)C
MDL No. :MFCD04973932
InChI Key :FNNJFDXFLFLEAD-UHFFFAOYSA-N
Pubchem ID :2757268

Safety of [ 439692-55-4 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 439692-55-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 439692-55-4 ]

[ 439692-55-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 90924-12-2 ]
  • [ 439692-55-4 ]
  • 6-tert-butyl-4-[(3-phenylisoxazol-5-yl)-methoxy]-thieno[2,3-d]pyrimidine [ No CAS ]
YieldReaction ConditionsOperation in experiment
75% With triethylamine; In isopropyl alcohol; at 0 - 20℃; General procedure: (0.184 g,1 mmol) was added into a 25 mL one-necked round-bottom flask with 5mL of dry iso-PrOH, and the mixture was stirred in a cold bath. Then a solution of Et3N (0.101 g, 1 mmol) and <strong>[90924-12-2](3-phenyl-isoxazole-5-yl)-methanol</strong> (0.175 g, 1 mmol) in 10mL dry iso-PrOH was slowly added to the reaction system using a syringe. The mixture was stirred in a cold bath for an additional 30 min, and then tem-perature was allowed to reach room temperature. After reaction completion (monitored by thin layer chromatography, TLC), the reaction mixture was evaporated under reduced pressure, and the residue was purified by column chromatog-raphy on silica gel using petroleum ether and ethyl acetate (V/V, 5:1?2:1) as eluant. Fractions with similar Rf values were combined to obtain the target compound 3a.
 

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[ 439692-55-4 ]

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