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Chemical Structure| 4445-49-2 Chemical Structure| 4445-49-2

Structure of 4445-49-2

Chemical Structure| 4445-49-2

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Product Details of [ 4445-49-2 ]

CAS No. :4445-49-2
Formula : C14H10O4
M.W : 242.23
SMILES Code : O=C(C1=C(C(O)=O)C=CC=C1C2=CC=CC=C2)O

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Application In Synthesis of [ 4445-49-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 4445-49-2 ]

[ 4445-49-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 76350-90-8 ]
  • [ 4445-49-2 ]
YieldReaction ConditionsOperation in experiment
With potassium permanganate; cetyltrimethylammonim bromide; In water; at 0 - 70℃; for 64h; 15 g of 2-methyl-3-biphenylmethanol and 75 mg cetyltrimethylammonium bromide were added to 150 ml of water, and the resultant mixture was cooled to 0 C. in an ice bath. 48 g of potassium permanganate was added to the cold mixture and reaction was stirred at 0 C. for 10 min., at room temperature for 16 h, then at 70 C. for 48 h. The clear solution containing black solid was filtered through a pad of celite, and washed with 100 ml of dichloromethane. The aqueous solution was then acidified to pH 3 with 6 N aqueous hydrochloric acid and extracted four times with 150 ml portions of ethyl acetate. The combined organic fractions were dried over anhydrous sodium sulfate, and concentrated to 12.9 g of product; 1H NMR (d6-DMSO): delta=7.28-7.46 (m, 5 H), 7.51-7.61 (m, 2 H), 7.84-7.89 (dd, 1H), 13.0 (s, 2H).
 

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