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Chemical Structure| 44806-45-3 Chemical Structure| 44806-45-3

Structure of 44806-45-3

Chemical Structure| 44806-45-3

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Product Details of [ 44806-45-3 ]

CAS No. :44806-45-3
Formula : C5H6Cl2O2
M.W : 169.00
SMILES Code : O=C(C(CC(Cl)=O)C)Cl
MDL No. :N/A

Safety of [ 44806-45-3 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H314
Precautionary Statements:P280-P305+P351+P338-P310
Class:8
UN#:3265
Packing Group:

Application In Synthesis of [ 44806-45-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 44806-45-3 ]

[ 44806-45-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 66655-67-2 ]
  • [ 44806-45-3 ]
  • 6-(3-Carboxy-propionyl)-3,4-dihydro-2(1H)-quinazolinone [ No CAS ]
YieldReaction ConditionsOperation in experiment
With hydrogenchloride;aluminium trichloride; In carbon disulfide; Step 1. 6-(3-Carboxy-propionyl)-<strong>[66655-67-2]3,4-dihydro-2(1H)-quinazolinone</strong> 3,4-Dihydro-2(1H)-quinazolinone (4.8 g) is added to a stirred suspension of anhydrous aluminum chloride (21.7 g) in carbon disulfide (100 ml) under nitrogen. Methyl succinyl chloride (4.9 g) is added dropwise to the stirred suspension, the reaction mixture refluxed for about 70 hours, cooled to RT and the liquid phase decanted. The residue is treated with ice and 6N HCl, filtered, and the solid air dried, affording the desired crude product, M.P. 176-180 C., which is used in the next step without further purification.
 

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