Home Cart Sign in  
Chemical Structure| 4553-59-7 Chemical Structure| 4553-59-7

Structure of 4553-59-7

Chemical Structure| 4553-59-7

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 4553-59-7 ]

CAS No. :4553-59-7
Formula : C14H12N2
M.W : 208.26
SMILES Code : N#CC(NC1=CC=CC=C1)C2=CC=CC=C2
MDL No. :MFCD00019793

Safety of [ 4553-59-7 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H318-H400
Precautionary Statements:P273-P280-P305+P351+P338-P310-P391-P501
Class:9
UN#:3077
Packing Group:

Application In Synthesis of [ 4553-59-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 4553-59-7 ]

[ 4553-59-7 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 4553-59-7 ]
  • [ 3684-12-6 ]
  • 2
  • [ 2568-25-4 ]
  • [ 7677-24-9 ]
  • [ 62-53-3 ]
  • [ 4553-59-7 ]
YieldReaction ConditionsOperation in experiment
76% With hafnium tetrachloride; In acetonitrile; at 20℃; for 0.5h;Inert atmosphere; General procedure: Acetal (1.2 mmol), aromatic amine (1.0 mmol), TMSCN (0.165 mL,1.3 mmol), and HfCl4 (0.064 g, 0.2 mol) were added to a flask (25 mL),followed by addition of acetonitrile (4.0 mL) under argon. The mixturewas stirred at room temperature and monitored by TLC. The solutionwas then diluted with dichloromethane (5.0 mL), washed with brine.The aqueous layer was extracted with CH2Cl2 (3 × 10 mL), the combinedorganic layer was dried over MgSO4, filtered, and evaporated undervacuum. The residue was purified by column chromatography on silicagel (petroleum ether) to afford the desired product.2-Phenyl-2-(phenylamino)acetonitrile: White solid, m.p. 76?77 °C(lit.20 76?78 °C); yield 91percent (Table 3, entry 1), 76percent (Table 3, entry 8) and75percent (Table 3, entry 12); 1H NMR (400 MHz, CDCl3) delta 7.53 (dd, J = 7.5,1.9 Hz, 2H), 7.44?7.36 (m, 3H), 7.24?7.18 (m, 2H), 6.83 (t, J = 7.4 Hz, 1H),6.71 (d, J = 8.2 Hz, 2H), 5.36 (s, 1H), 3.96 (s, 1H).
 

Historical Records