Alternatived Products of [ 470668-97-4 ]
Product Details of [ 470668-97-4 ]
CAS No. : | 470668-97-4 |
MDL No. : | MFCD18642716 |
Formula : |
C13H23NO4
|
Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | CHDNLIOSLJNCQY-UHFFFAOYSA-N |
M.W : |
257.33
|
Pubchem ID : | 11219084 |
Synonyms : |
|
Safety of [ 470668-97-4 ]
Application In Synthesis of [ 470668-97-4 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 470668-97-4 ]
- 1
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[ 153749-89-4 ]
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[ 470668-97-4 ]
- 2
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[ 470668-97-4 ]
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[ 89115-93-5 ]
Yield | Reaction Conditions | Operation in experiment |
|
With hydrogenchloride In dichloromethane; ethyl acetate for 0.333333h; |
(2-Methylpiperidin-2-yl)methanol
Methyl N-Boc-2-methylpiperidine-2-carboxylate (5.0g,19.45mmol) was dissolved in dichloromethane (15mL),Hydrogen chloride ethyl acetate solution (30 mL) was added,and the reaction solution was concentrated after 20 minutes. Add dichloromethane (20 mL) and sodium carbonate solid to adjust the pH to 7-8. Filtration and concentration of the filtrate gave the crude product of methyl 2-methylpiperidine-2-carboxylate,which was dissolved in tetrahydrofuran (20 mL). This solution was added dropwise to a solution of lithium aluminum hydride in tetrahydrofuran (30 mL,23.3 mmol) at 0°C,stirred at 0°C for 2 hours,quenched by sodium sulfate decahydrate,stirred at room temperature for 30 minutes,filtered,and the filtrate was concentrated to obtain the title compound (1.8 g,72%). |