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Chemical Structure| 484679-02-9 Chemical Structure| 484679-02-9

Structure of 484679-02-9

Chemical Structure| 484679-02-9

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Product Details of [ 484679-02-9 ]

CAS No. :484679-02-9
Formula : C16H27NO4
M.W : 297.39
SMILES Code : COCCOCCN(CCOCCOC)C1=CC=CC=C1

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Application In Synthesis of [ 484679-02-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 484679-02-9 ]

[ 484679-02-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 16427-44-4 ]
  • [ 120-07-0 ]
  • [ 484679-02-9 ]
YieldReaction ConditionsOperation in experiment
42% With sodium hydride; In acetonitrile; for 34h;Inert atmosphere; Reflux; N,N-phenyldiethanolamine (3, 3.6 g, 0.02 mol) was dissolved in dry acetonitrile (120 ml) in a two neck round-bottomed flask that was purged with argon. Then, sodium hydride (1.44 g, 0.06 mol) was slowly added to the solution in order to deprotonate compound 3. Afterward, a solution of 2 (7.7 g, 0.05 mol) in acetonitrile (20 ml) was added dropwise under argon and the crude was stirred at reflux for 34 h. Then, the crude was filtered off and acetonitrile was evaporated. The crude was purified by column chromatography using aluminum oxide as stationary phase and hexane-ethyl acetate 7:3 v/v as eluent. Product 4 was isolated as yellow oil (42%, 0.0084 mol).
 

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