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Chemical Structure| 4915-97-3 Chemical Structure| 4915-97-3

Structure of 4915-97-3

Chemical Structure| 4915-97-3

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Product Details of [ 4915-97-3 ]

CAS No. :4915-97-3
Formula : C11H11N3O2
M.W : 217.22
SMILES Code : O=C(OCC)C1=CN(C2=CC=CC=C2)N=N1
MDL No. :MFCD01836533

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Application In Synthesis of [ 4915-97-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 4915-97-3 ]

[ 4915-97-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 4915-97-3 ]
  • [ 103755-58-4 ]
YieldReaction ConditionsOperation in experiment
89% Step 1 Synthesis of (1-Phenyl-1H-[1,2,3]triazol-4-yl)-methanol A stirred solution of 1-phenyl-1H-[1,2,3]triazole-4-carboxylic acid ethyl ester (prepared by a procedure similar to that described in Steps 1-3 of General Scheme 1) (269 mg, 1.25 mmol) in THF (6 mL) was heated to reflux. To the heated reaction mixture was added sodium borohydride (395 mg, 10.4 mmol) portionwise over a period of 15 minutes, followed by dropwise addition of MeOH (2.4 mL). Stirring was continued at reflux temperature for 1 hr. The reaction mixture was then quenched with ammonium chloride solution and the product was extracted with ethyl acetate. The organic layer was washed with saturated brine solution, dried over sodium sulfate and concentrated under reduced pressure to afford 245 mg (89%) of (1-phenyl-1H-[1,2,3]triazol-4-yl)-methanol.
 

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