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Chemical Structure| 496061-80-4 Chemical Structure| 496061-80-4

Structure of 496061-80-4

Chemical Structure| 496061-80-4

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Product Details of [ 496061-80-4 ]

CAS No. :496061-80-4
Formula : C13H16O3
M.W : 220.31
SMILES Code : O=C(OCC)C[C@@H]1CCC2=C1C=CC(O)=C2
MDL No. :MFCD30803228

Safety of [ 496061-80-4 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 496061-80-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 496061-80-4 ]

[ 496061-80-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 496061-80-4 ]
  • [ 221037-98-5 ]
  • [ 1022980-04-6 ]
YieldReaction ConditionsOperation in experiment
With pyridine; copper diacetate; In dichloromethane; at 20℃;4A molecular sieves; To a stirred solution of Intemediate 1 (1.9 g, 8.5 mmol) in dichloromethane (20 mL) was added 3- iodophenylboronic acid (3.0 g, 12.1 mmol), copper(II) acetate (2.0 g, 11 mmol), pyridine (3.2 mL, 40 mmol), and 4A molecular sieves (~2.5 g). The resulting mixture was stirred under an oxygen balloon at room temperature overnight. The reaction mixuture was filtered, washed with dichloromethane, and concentrated. The greenish crude product was purified on a silica gel column, eluting with ethyl acetate (20-50percent) in hexanes to afford the desired product. LCMS for C 19Hl 9103: calc. 422, observed 423 [M+H].
 

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