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Chemical Structure| 496808-03-8 Chemical Structure| 496808-03-8

Structure of 496808-03-8

Chemical Structure| 496808-03-8

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Product Details of [ 496808-03-8 ]

CAS No. :496808-03-8
Formula : C11H23N3
M.W : 197.32
SMILES Code : CN1CC(CN2CCNCC2)CCC1
MDL No. :MFCD02093538

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Application In Synthesis of [ 496808-03-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 496808-03-8 ]

[ 496808-03-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 496808-03-8 ]
  • [ 445-13-6 ]
  • N-[3-chloro-4-(trifluoromethyl)phenyl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
iV-tS-CIiloro^-CtrifluoromethylJphenyy^-fCl-methylpiperidin-S- yl)methyl]pipera-ne-l-carboxaniotaide; To a solution of di-tert-butyl dicarbonate (114.6 mg) in chloroform (2 ml) was added 4-dimethylaminopyridine (6 mg). A solution of 4-amino-2-chlorobenzotrifluoride(98.1 mg) in chloroform (2 ml) was added and the reaction mixture stirred for 20 minutes at room temperature. A solution of l-[(l-methylpiperidm-3-yl)methyl]piperazine (98.5 mg) in chloroform (2 ml) was added and the resulting solution was stirred at reflux for 18 hours. The reaction mixture was purified by column chromatography on silica gel (20 g) using a gradient of 100% dichloromethane through to 20% methanolic ammonia in dichloromethane to give the title compound (14 mg).
 

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