Home Cart Sign in  
Chemical Structure| 63984-03-2 Chemical Structure| 63984-03-2
Chemical Structure| 63984-03-2

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of 5-Aminopentanoic acid tert-butyl ester

CAS No. :63984-03-2
Formula : C9H19NO2
M.W : 173.25
SMILES Code : O=C(OC(C)(C)C)CCCCN
MDL No. :MFCD08275839
InChI Key :ZJUJPZBBBNJPTI-UHFFFAOYSA-N
Pubchem ID :10607312

Safety of 5-Aminopentanoic acid tert-butyl ester

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Application In Synthesis of 5-Aminopentanoic acid tert-butyl ester

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 63984-03-2 ]

[ 63984-03-2 ] Synthesis Path-Downstream   1~4

  • 1
  • [ 5926-51-2 ]
  • [ 63984-03-2 ]
  • C13H20BrNO5 [ No CAS ]
YieldReaction ConditionsOperation in experiment
In N,N-dimethyl-formamide; General procedure: Amino compound 37 or 38 (6 g) in DMF (60 ml) was added <strong>[5926-51-2]bromomaleic anhydride</strong> (1 eq) or 2,3-dibro- momaleic anhydride (1 eq) and the mixture was stirred overnight, evaporated via oil pump to dryness to afford the crude enoic acids. To the crude enoic acids were added HOAc (.-50 ml) and Ac20 (2.4 g) and the reaction mixture was fluxed at 120° C. for 6.-12 h, concentrated and purified on 5i02 colunm eluted with EtOAc/CH2C12 (1:1 01 :1) to afford (61percent 87percent yield) of the 3?-bromo-maleimdo compounds 39 and 40, and 3?,4?-dibromo-maleimdo compounds 43 and 44 respectively
  • 2
  • [ 5926-51-2 ]
  • [ 63984-03-2 ]
  • 5-(3-bromo-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)pentanoic acid [ No CAS ]
YieldReaction ConditionsOperation in experiment
With acetic anhydride; acetic acid; In N,N-dimethyl-formamide; at 120℃; General procedure: After dissolving the compound 37 or 38 (~ 6 g) in DMF (60 mL), <strong>[5926-51-2]bromomaleic anhydride</strong> (1 eq) or 2,3-dibromo-maleic anhydride (1 eq) was added and the reaction The mixture was stirred overnight. The reaction solution was concentrated to dryness, and pure trans acid was obtained. Acetic acid (~ 50 mL) and acetic anhydride (2 to 4 g) were added to the trans acid and the reaction mixture was refluxed at 120 ° C. for 6 to 12 hours. The reaction solution was concentrated and then separated by silica gel column chromatography (ethyl acetate / dichloromethane = 1: 10 to 1: 1) to give 3'-bromo-maleimide compounds 39 and 40. By the same process, 3 ', 4'-dibromo-maleimide compounds 43, 44 were obtained (61percent to 87percent).
  • 3
  • [ 1122-12-9 ]
  • [ 63984-03-2 ]
  • 5-(3,4-dibromo-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)pentanoic acid [ No CAS ]
YieldReaction ConditionsOperation in experiment
With acetic anhydride; acetic acid; In N,N-dimethyl-formamide; at 120℃; General procedure: After dissolving the compound 37 or 38 (~ 6 g) in DMF (60 mL), bromomaleic anhydride (1 eq) or <strong>[1122-12-9]2,3-dibromo-maleic anhydride</strong> (1 eq) was added and the reaction The mixture was stirred overnight. The reaction solution was concentrated to dryness, and pure trans acid was obtained. Acetic acid (~ 50 mL) and acetic anhydride (2 to 4 g) were added to the trans acid and the reaction mixture was refluxed at 120 ° C. for 6 to 12 hours. The reaction solution was concentrated and then separated by silica gel column chromatography (ethyl acetate / dichloromethane = 1: 10 to 1: 1) to give 3'-bromo-maleimide compounds 39 and 40. By the same process, 3 ', 4'-dibromo-maleimide compounds 43, 44 were obtained (61percent to 87percent).
  • 4
  • [ 5926-51-2 ]
  • [ 63984-03-2 ]
  • C13H20BrNO5 [ No CAS ]
YieldReaction ConditionsOperation in experiment
In N,N-dimethyl-formamide; Dissolve compound 37 or 38 (~ 6g) in DMF (60mL), then add <strong>[5926-51-2]bromomaleic anhydride</strong> (1eq) or 2,3-dibromo-maleic anhydride (1eq), and stir the reaction mixture. overnight.The reaction solution was concentrated to dryness to obtain pure trans acid.To the above trans acid were added acetic acid (-50 mL) and acetic anhydride (2 to 4 g), and the reaction mixture was refluxed at 120 C for 6 to 12 hours.The reaction solution was concentrated and separated on a silica gel column (ethyl acetate / dichloromethane = 1:10 to 1: 1) to obtain 3'-bromo-maleimide compounds 39 and 40. 3 ', 4 were obtained in the same manner. '-Dibromo-maleimide compounds 43 and 44 (61% to 87%).
 

Historical Records

Technical Information

Categories