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Chemical Structure| 501917-22-2 Chemical Structure| 501917-22-2

Structure of 501917-22-2

Chemical Structure| 501917-22-2

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Product Details of [ 501917-22-2 ]

CAS No. :501917-22-2
Formula : C9H10ClNO
M.W : 183.64
SMILES Code : OC1C2=C(N=C(Cl)C=C2)CCC1
MDL No. :MFCD08692080

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Application In Synthesis of [ 501917-22-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 501917-22-2 ]

[ 501917-22-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 124467-36-3 ]
  • [ 501917-22-2 ]
YieldReaction ConditionsOperation in experiment
With sodium tetrahydroborate; In methanol; at 20℃; for 2h; To a mixture of <strong>[124467-36-3]2-chloro-7,8-dihydroquinolin-5(6H)-one</strong> (A-l) (2.50 g, 13.77 mmol) in MeOH (41.7 ml) at RT was added NaBEE (0.521 g, 13.77 mmol). The mixture was stirred for 2 h before it was quenched with a saturated solution of NEECl (100 mL), extracted with EtOAc (100 mL x 3), dried over Na2S04, and concentrated. The residue was purified by column chromatography on silica (2-60% 3: 1 EtOAc:EtOH/hexanes) to afford the title compound. MS: 183.9 (M+l).
 

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