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Chemical Structure| 502-41-0 Chemical Structure| 502-41-0

Structure of 502-41-0

Chemical Structure| 502-41-0

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Product Details of [ 502-41-0 ]

CAS No. :502-41-0
Formula : C7H14O
M.W : 114.19
SMILES Code : OC1CCCCCC1
MDL No. :MFCD00004150
InChI Key :QCRFMSUKWRQZEM-UHFFFAOYSA-N
Pubchem ID :10399

Safety of [ 502-41-0 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H227-H315
Precautionary Statements:P210-P280-P370+P378-P403+P235-P501

Application In Synthesis of [ 502-41-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 502-41-0 ]

[ 502-41-0 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 180995-12-4 ]
  • [ 502-41-0 ]
  • [ 868065-62-7 ]
  • 2
  • [ 180995-12-4 ]
  • [ 502-41-0 ]
  • [ 868065-64-9 ]
  • 3
  • [ 32315-10-9 ]
  • [ 502-41-0 ]
  • [ 6557-86-4 ]
YieldReaction ConditionsOperation in experiment
In dichloromethane; Compound 10 (0.357mg, 1.54mmol) was added dropwise to a solution of triethylamine (0.539mL, 3.99mmol) and cycloheptylchloroformate (0.705g, 3.99mmol) (previously prepared with a reaction between BTC (Bis(trichloromethyl) carbonate) and cycloheptanol) in anhydrous dichloromethane (12mL). The reaction mixture was stirred at room temperature for 4h. After that, the resulting solution was washed three times with water, dried over Na2SO4, filtered and evaporated under reduced pressure. The brown oil obtained was purified by flash chromatography on silica gel (3:7 hexane-ethyl acetate) and subsequently washed with hexane to afford compound 31. Brown oil (0.042g, 0.113mmol, Yield: 7%). 1H NMR (CDCl3) δ: 7.29-7.26 (m, 2H, Ar-H), 7.04-7.00 (m, 3H, Ar-H, H6-Py), 6.78 (bs, 1H, NH), 6.09 (d, 1H, J=6.8Hz, H5-Py), 5.07 (s, 2H, PhCH2N), 4.85-4.83 (m, 1H, CHO), 2.18 (s, 3H, CH3-Py), 1.98-1.93 (m, 2H, CH2), 1.74-1.46 (m, 10H, 5×CH2).
 

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