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Chemical Structure| 50534-08-2 Chemical Structure| 50534-08-2

Structure of 50534-08-2

Chemical Structure| 50534-08-2

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Product Details of [ 50534-08-2 ]

CAS No. :50534-08-2
Formula : C14H21N3O
M.W : 247.34
SMILES Code : O=C(C1=CC=C(N)C=C1)N2CCC(N(C)C)CC2
MDL No. :MFCD12439382

Safety of [ 50534-08-2 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

Application In Synthesis of [ 50534-08-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 50534-08-2 ]

[ 50534-08-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 50534-08-2 ]
  • [ 1197159-91-3 ]
  • [ 1885-14-9 ]
  • [ 1197160-78-3 ]
YieldReaction ConditionsOperation in experiment
17.8% 0.43 g of <strong>[1197159-91-3]4-(4,6-dimorpholino-1,3,5-triazin-2-yl)aniline</strong> (1.26 mmol) was dissolved in 5 mL of DMF, then 0.23 g of pyridine (3 mmol) was added and placed In the ice bath, the temperature is below 5 C,0.18 g of phenyl chloroformate (1.15 mmol) dissolved in 3 mL of DMF was added dropwise. After the addition is completed,The reaction was carried out at room temperature. After completion of the reaction, 0.27 g of (4-aminophenyl)(4-(dimethylamino)piperidin-1-yl)methanone (1.1 mmol) was added, and the mixture was heated to 90 C for 12 h.After the reaction was completed, the reaction solution was poured into 50 mL of water, a large amount of solid was precipitated, stirred for 20 min, and suction filtered to give a solid.0.2g. The purification was carried out by column chromatography, and the mobile phase was obtained by DCM: methanol: methanol ammonia solution = 10:1: 0.2, and finally, 0.11 g of solid was obtained, yield 17.8%.
 

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