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Chemical Structure| 50789-43-0 Chemical Structure| 50789-43-0

Structure of 50789-43-0

Chemical Structure| 50789-43-0

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Product Details of [ 50789-43-0 ]

CAS No. :50789-43-0
Formula : C14H12O3
M.W : 228.24
SMILES Code : O=C(OC)C1=CC=CC(OC2=CC=CC=C2)=C1
MDL No. :MFCD00017192
Boiling Point : No data available
InChI Key :GWNMDCSPTJONPD-UHFFFAOYSA-N
Pubchem ID :198261

Safety of [ 50789-43-0 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 50789-43-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 50789-43-0 ]

[ 50789-43-0 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 618-89-3 ]
  • [ 108-95-2 ]
  • [ 50789-43-0 ]
YieldReaction ConditionsOperation in experiment
73% With thio-xanthene-9-one; (2,2'-bipyridine)nickel(II) dibromide; N-tert-butylisopropylamine; In acetonitrile; for 72h;Inert atmosphere; Irradiation; Green chemistry; Methyl 3-bromobenzoate (0.2 mmol), phenol (0.6 mmol), TXO (20 mol %), Ni(bpy)Br2 (10 mol %), t-BuNH(i-Pr) (0.4 mmol) and MeCN (3 mL) was added to a dry reaction tube with a magnetic stir bar, then the reaction tube was replaced with N2 3 times, and the reaction was stirred for 72 hours under 45 W CFL irradiation. After the reaction, 5 mL of water was added, then extracted with 3×5 mL of ethyl acetate, the organic phases were combined, the organic phases were dried over anhydrous sodium sulfate, filtered, the filtrate was concentrated by rotary evaporation, and separated by silica gel column chromatography to obtain The target product (73% yield).
  • 2
  • [ 75888-21-0 ]
  • [ 2905-65-9 ]
  • [ 50789-43-0 ]
YieldReaction ConditionsOperation in experiment
With sodium phenoxide;copper(I) chloride; In methoxybenzene; EXAMPLE 10 Preparation of methyl meta-phenoxybenzoate, STR40 from sodium phenolate, STR41 and <strong>[2905-65-9]methyl meta-chlorobenzoate</strong>, STR42 in the presence of cuprous chloride, CuCl, and tris-(3,6-dioxaoctyl)-amine. 17.1 g (0.098 mol) of <strong>[2905-65-9]methyl meta-chlorobenzoate</strong>, 11.6 g (0.1 mol) of sodium phenate, 1 g (0.001 mol) of cuprous chloride and 3.7 g (0.001 mol) of tris-(3,6-dioxaoctyl)-amine in 300 g of anisole were introduced into a 1 liter round-bottomed flask equipped as in Example 1. After refluxing for 6 hours, the degree of conversion was 75%.
 

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